Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Adam Ciesiolka"'
Autor:
Vasso Makrantoni, Adam Ciesiolka, Conor Lawless, Josefin Fernius, Adele Marston, David Lydall, Michael J. R. Stark
Publikováno v:
G3: Genes, Genomes, Genetics, Vol 7, Iss 9, Pp 3203-3215 (2017)
The chromosomal passenger complex (CPC) is a key regulator of eukaryotic cell division, consisting of the protein kinase Aurora B/Ipl1 in association with its activator (INCENP/Sli15) and two additional proteins (Survivin/Bir1 and Borealin/Nbl1). Her
Externí odkaz:
https://doaj.org/article/6d523842358f4a3a8279c80c986ab2e2
Autor:
Adam Ciesiolka, Grzegorz Figura, Katarzyna Rolle, Maciej Borowiec, Bogusław Tymoniuk, Julia Latowska, Paweł Zmora, Agnieszka Fiszer, Adriana Grabowska, Paweł Joachimiak, Luiza Handschuh
Publikováno v:
Przeglad Epidemiologiczny. :14-26
INTRODUCTION. Since the SARS-CoV-2 emergence in 2019/2020, at least 158 million infections with this pathogen have been recorded, of which 3.29 million infected people have died. Due to the non-specific symptoms of SARS-CoV-2 infection, laboratory te
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c933337bad2c216a13d011ce6ea61f6f
https://doi.org/10.32394/pe.75.02
https://doi.org/10.32394/pe.75.02
Autor:
Wlodzimierz J. Krzyzosiak, Agata Ciolak, Michał Michalak, Agnieszka Fiszer, Marta Olejniczak, Katarzyna Dorota Raczynska, Dominika Zielinska, Magdalena Wozna-Wysocka, Adam Ciesiolka, Emilia Kozlowska, Magdalena Dabrowska, Paweł Joachimiak, Anna Stroynowska-Czerwinska
Publikováno v:
Cellular and Molecular Life Sciences
Polyglutamine (polyQ) diseases are incurable neurological disorders caused by CAG repeat expansion in the open reading frames (ORFs) of specific genes. This type of mutation in the HTT gene is responsible for Huntington’s disease (HD). CAG repeat-t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a25718ab82051ef201a0c9c461d5a37c
http://europepmc.org/articles/PMC7904544
http://europepmc.org/articles/PMC7904544
Autor:
Magdalena Jazurek-Ciesiolka, Pawel M. Switonski, Maciej Figiel, Agnieszka Fiszer, Paula Sobieszczanska, Dorota Wronka, Lukasz Przybyl, Joanna Suszynska-Zajczyk, Adam Ciesiolka, Grzegorz Figura, Magdalena Wozna-Wysocka, Julia O. Misiorek, Wlodzimierz J. Krzyzosiak
Publikováno v:
B: Models for HD.
Background Experiments with HD mouse models allow for insight into detailed molecular pathways disrupted in the course of disease development. New aspects of HD pathology need to be determined to bring additional targets and hints for therapeutic app
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0c049d2af58ea8a860c188df504977dc
https://doi.org/10.1136/jnnp-2021-ehdn.23
https://doi.org/10.1136/jnnp-2021-ehdn.23
Autor:
Alicja A. Komur, Adam Ciesiolka, Agnieszka Fiszer, Wlodzimierz J. Krzyzosiak, Magdalena Jazurek-Ciesiolka, Martyna Olga Urbanek-Trzeciak
Publikováno v:
Journal of molecular biology. 432(24)
Spinocerebellar ataxia type 3 (SCA3) is a progressive neurodegenerative disorder caused by a CAG repeat expansion in the ATXN3 gene encoding the ataxin-3 protein. Despite extensive research the exact pathogenic mechanisms of SCA3 are still not unders
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1ca8a007206a528c22082dead10b6699
https://pubmed.ncbi.nlm.nih.gov/33157084
https://pubmed.ncbi.nlm.nih.gov/33157084
Autor:
Stephen Gregory Addinall, Eva-Maria Holstein, Conor Lawless, Min Yu, Kaye Chapman, A Peter Banks, Hien-Ping Ngo, Laura Maringele, Morgan Taschuk, Alexander Young, Adam Ciesiolka, Allyson Lurena Lister, Anil Wipat, Darren James Wilkinson, David Lydall
Publikováno v:
PLoS Genetics, Vol 7, Iss 4, p e1001362 (2011)
To better understand telomere biology in budding yeast, we have performed systematic suppressor/enhancer analyses on yeast strains containing a point mutation in the essential telomere capping gene CDC13 (cdc13-1) or containing a null mutation in the
Externí odkaz:
https://doaj.org/article/9b28f9f63e7b434e899130efd26f9f54
Autor:
Wlodzimierz J. Krzyzosiak, Adam Ciesiolka, Katarzyna Bilinska, Julia Starega-Roslan, Magdalena Jazurek
Publikováno v:
Nucleic Acids Research
RNA-protein complexes play a central role in the regulation of fundamental cellular processes, such as mRNA splicing, localization, translation and degradation. The misregulation of these interactions can cause a variety of human diseases, including
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bcce1722c215c38e7c73b2fc630c235e
http://europepmc.org/articles/PMC5100574
http://europepmc.org/articles/PMC5100574
Autor:
Paweł Joachimiak, Paweł M Świtoński, Emilia Kozlowska, Agata Łużna, Wlodzimierz J. Krzyzosiak, Łukasz Przybył, Magdalena Woźna-Wysocka, Agnieszka Fiszer, Adam Ciesiolka, Magdalena Jazurek-Ciesiolka, Michał Michalak
Publikováno v:
Experimental therapeutics – preclinical.
In development of therapeutic strategy for Huntington’s disease (HD) targeting mutation site directly to inhibit selectively the expression of mutant gene is an attractive option. We have previously described CAG repeat-targeting siRNAs with specif
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a2409f0058aa233e6d6d1ec4510a86ea
https://doi.org/10.1136/jnnp-2018-ehdn.239
https://doi.org/10.1136/jnnp-2018-ehdn.239
Publikováno v:
Frontiers in Cellular Neuroscience
Short Tandem Repeats (STRs) are frequent entities in many transcripts, however, in some cases, pathological events occur when a critical repeat length is reached. This phenomenon is observed in various neurological disorders, such as myotonic dystrop
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::049fff6777640e2f0d7a39407e11e0dd
https://doi.org/10.3389/fncel.2017.00097
https://doi.org/10.3389/fncel.2017.00097
Autor:
Alexander I. Young, Min Yu, Morgan Taschuk, Darren J. Wilkinson, Conor Lawless, Hien-Ping Ngo, David Lydall, Laura Maringele, Adam Ciesiolka, Eva-Maria Holstein, Stephen G. Addinall, Allyson L. Lister, A. Peter Banks, Anil Wipat, Kaye Chapman
Publikováno v:
PLoS Genetics
PLoS Genetics, Vol 7, Iss 4, p e1001362 (2011)
PLoS Genetics, Vol 7, Iss 4, p e1001362 (2011)
To better understand telomere biology in budding yeast, we have performed systematic suppressor/enhancer analyses on yeast strains containing a point mutation in the essential telomere capping gene CDC13 (cdc13-1) or containing a null mutation in the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aa87b054549537091028e953c5529aac
https://pubmed.ncbi.nlm.nih.gov/21490951
https://pubmed.ncbi.nlm.nih.gov/21490951