Zobrazeno 1 - 10
of 61
pro vyhledávání: '"Adam Cawley"'
Autor:
Christopher C. J. Fitzgerald, Rikard Hedman, Dimanthi R. Uduwela, Bettina Paszerbovics, Adam J. Carroll, Teresa Neeman, Adam Cawley, Lance Brooker, Malcolm D. McLeod
Publikováno v:
Frontiers in Molecular Biosciences, Vol 9 (2022)
The study of urinary phase II sulfate metabolites is central to understanding the role and fate of endogenous and exogenous compounds in biological systems. This study describes a new workflow for the untargeted metabolic profiling of sulfated metabo
Externí odkaz:
https://doaj.org/article/5871e93fb4b641918ef1e182aeacb56c
Publikováno v:
Molecules, Vol 28, Iss 1, p 312 (2022)
The current approach to equine anti-doping is focused on the targeted detection of prohibited substances. However, as new substances are rapidly being developed, the need for complimentary methods for monitoring is crucial to ensure the integrity of
Externí odkaz:
https://doaj.org/article/660294f0ebaf43db969fa006a6ce2d38
Publikováno v:
Frontiers in Chemistry, Vol 7 (2019)
The continual introduction of a large number of new psychoactive substances, along with the large turnover of these substances, necessitates the development of non-targeted detection strategies to keep pace with the ever-changing drug market. The pro
Externí odkaz:
https://doaj.org/article/b02a42bcb8af4c7baff1778374c51813
Publikováno v:
Drug Testing and Analysis. 14:983-990
The concept of biomarker measurements in the form of a ratio has not been explored in detail. This is surprising considering the current and future potential for biomarkers incorporating endogenous reference compounds (ERCs) in a range of fields. A s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1707a7c24f9ba968ad55d1ed217e3b8e
https://doi.org/10.1002/dta.3250
https://doi.org/10.1002/dta.3250
Publikováno v:
Drug Testing and Analysis. 14:794-807
Metabolomics is a multidisciplinary field providing workflows for complementary approaches to conventional analytical determinations. It allows for the study of metabolically related groups of compounds or even the study of novel pathways within the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::462f48c14662896340de915d838f6cb0
https://doi.org/10.1002/dta.3245
https://doi.org/10.1002/dta.3245
Publikováno v:
Klingberg, J, Keen, B, Cawley, A, Pasin, D & Fu, S 2022, ' Developments in high-resolution mass spectrometric analyses of new psychoactive substances ', Archives of Toxicology, vol. 96, pp. 949–967 . https://doi.org/10.1007/s00204-022-03224-2
The proliferation of new psychoactive substances (NPS) has necessitated the development and improvement of current practices for the detection and identification of known NPS and newly emerging derivatives. High-resolution mass spectrometry (HRMS) is
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8a0519a58eac6a62bdcf9f5bcbf701cf
https://doi.org/10.1007/s00204-022-03224-2
https://doi.org/10.1007/s00204-022-03224-2
Autor:
Christopher C. J. Fitzgerald, Christopher Bowen, Madysen Elbourne, Adam Cawley, Malcolm D. McLeod
Publikováno v:
Journal of the American Society for Mass Spectrometry. 33(7)
The identification and confirmation of steroid sulfate metabolites in biological samples are essential to various fields, including anti-doping analysis and clinical sciences. Ultra-high-performance liquid chromatography with tandem mass spectrometry
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::864a9410ee399dc9c5bc288be38e6db1
https://pubmed.ncbi.nlm.nih.gov/35791638
https://pubmed.ncbi.nlm.nih.gov/35791638
Publikováno v:
Drug Testing and Analysis. 13:894-902
Androgens, both steroidal and nonsteroidal in nature, are among the most commonly misused substances in competitive sports. Their recognized anabolic and performance enhancing effects through short- and long-term physiological adaptations make them p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::58c1ecc3cbaa4af9b9434f18ccb37ce8
https://doi.org/10.1002/dta.3049
https://doi.org/10.1002/dta.3049
Publikováno v:
Drug Testing and Analysis. 13:990-1000
The constant evolution of the illicit drug market makes the identification of unknown compounds problematic. Obtaining certified reference materials for a broad array of new analogues can be difficult and cost prohibitive. Machine learning provides a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::255aab92f52fc5505d8d20f12ca52dff
https://doi.org/10.1002/dta.2976
https://doi.org/10.1002/dta.2976
Publikováno v:
Toxicologie Analytique et Clinique. 34:S55-S56
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8f352e4feaac4c222c863cafa265fcd3
https://doi.org/10.1016/j.toxac.2022.06.068
https://doi.org/10.1016/j.toxac.2022.06.068