CLL-048 Frequency of Practice-Changing Findings Identified by Comprehensive Genomic Profiling in Non-Myeloid Hematologic Malignancies

Autor: Zhou, Katherine I., Lin, Chenyu, Green, Michelle, Adam Caughey, Bennett, Strickler, John H., Datto, Michael, McKinney, Matthew

Publikováno v: In Clinical Lymphoma, Myeloma and Leukemia September 2024 24 Supplement 1:S341-S341

Clinical impact of MAPK pathway alterations in advanced biliary tract cancer (BTC): SCRUM-Japan GOZILA and COLOMATE international collaboration

Autor: Hideaki Takahashi, Bennett Adam Caughey, Kumiko Umemoto, Michelle Green, Yoshiaki Nakamura, Michael Datto, Makoto Ueno, Daniel Walden, Taito Esaki, Thomas Oliver, Yoshito Komatsu, Nobumasa Mizuno, Eiji Oki, Hiroya Taniguchi, Hideaki Bando, Chigusa Morizane, Takayuki Yoshino, John H Strickler, Masafumi Ikeda, Tanios S. Bekaii-Saab

Publikováno v: Journal of Clinical Oncology. 40:4086-4086

4086 Background: Abnormalities in the MAPK pathway are potential therapeutic targets in various cancers. However, the clinical impact of alterations in the MAPK pathway in BTC have not been elucidated, especially outside of canonical mutations in KRA

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::7bab68a8378495971ee6a43b71b0a004
https://doi.org/10.1200/jco.2022.40.16_suppl.4086

Identification of an optimal circulating tumor DNA (ctDNA) shedding threshold to detect actionable driver mutations in colorectal and pancreatic adenocarcinoma

Autor: Bennett Adam Caughey, Kumiko Umemoto, Michelle Green, Masafumi Ikeda, Rachel D'Anna, Makoto Ueno, Donna Niedzwiecki, Hiroya Taniguchi, Daniel Walden, Yoshito Komatsu, Katherine I. Zhou, Taito Esaki, Ryne Ramaker, Tadamichi Denda, Michael Datto, Hideaki Bando, Tanios S. Bekaii-Saab, Takayuki Yoshino, John H Strickler, Yoshiaki Nakamura

Publikováno v: Journal of Clinical Oncology. 40:3571-3571

3571 Background: In colorectal cancer (CRC), mutations in KRAS, NRAS, and BRAF predict resistance to anti-EGFR therapies. In pancreatic ductal adenocarcinoma (PDAC), ~90% of patients harbor KRAS mutations, while KRAS wild-type tumors often have clini

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::fcc3f7ae32fec34e87ca54f3a7556e9f
https://doi.org/10.1200/jco.2022.40.16_suppl.3571

A novel sequencing-based vaginal health assay combining self-sampling, HPV detection and genotyping, STI detection, and vaginal microbiome analysis

Autor: Harold Nuñez, Amanda Morton, Nathaniel A. Walton, Kira Harman, Juan Cristobal Jimenez, Elisabeth M. Bik, Victor Alegria-Mera, Donna Marie B. Hongo, Laurens Kraal, Felipe Melis-Arcos, Raul Pino, Susan Zneimer, Ignacio Varas, Pamela A. Nieto, Richard Phan, Jessica Richman, Audrey D. Goddard, Luis E. Leon, Eduardo H. Morales, Glenn A. Carson, Patricia Vera-Wolf, Sarah Gupta, Zachary Apte, Sara W. Bird, Camila F. Navas, Cristian Bravo, Graham Gass, José M. Pérez-Donoso, Nicolás Órdenes-Aenishanslins, Juan Pablo Cárdenas, Daniel Almonacid, Denisse Bravo, Kwasi Addae, Eduardo Olivares, Francisco J. Ossandon, Katia Soto-Liebe, Paulo C. Covarrubias, Juan Pablo Bustamante, Juan A. Ugalde, Adam Caughey

Publikováno v: PLoS ONE, Vol 14, Iss 5, p e0215945 (2019)
PLoS ONE
CONICET Digital (CONICET)
Consejo Nacional de Investigaciones Científicas y Técnicas
instacron:CONICET

The composition of the vaginal microbiome, including both the presence of pathogens involved in sexually transmitted infections (STI) as well as commensal microbiota, has been shown to have important associations for a woman´s reproductive and gener

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::77ef7d3814522f61adbcbab0a3bbc67f
https://doi.org/10.1371/journal.pone.0215945