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pro vyhledávání: '"Adam C. Watkinson"'
Publikováno v:
Expert Opinion on Drug Delivery. 13:523-532
Transdermal drug delivery is the movement of drugs across the skin for absorption into the systemic circulation. Transfer of the drug can occur via passive or active means; passive transdermal products do not disrupt the stratum corneum to facilitate
Publikováno v:
Transdermal and Topical Drug Delivery: Principles and Practice
Preface ix About the Editors xi Contributors xiii Part One Current Science, Skin Permeation, and Enhancement Approaches 1. Skin Structure, Function, and Permeation 3 Heather A.E. Benson 2. Passive Skin Permeation Enhancement 23 Majella E. Lane, Paulo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d70e923d78e1d685ab2fcb8e1cb5bdfb
https://doi.org/10.1002/9781118140505
https://doi.org/10.1002/9781118140505
Publikováno v:
Skin Pharmacology and Physiology. 21:246-259
Microemulsions are thermodynamically stable colloidal dispersions of water and oil stabilized by a surfactant and, in many cases, also a cosurfactant. In the pharmaceutical field, microemulsions have been used as drug carriers for percutaneous, ocula
Autor:
Adam C. Watkinson, K.R. Brain
Publikováno v:
Journal of Toxicology: Cutaneous and Ocular Toxicology. 21:371-402
Autor:
Adam C Watkinson
Publikováno v:
British Menopause Society Journal. 7:105-108
Traditionally, hormone replacement therapy products have administered systemic doses of hormones utilising simple oral delivery. The major disadvantage of oral delivery is that it can lead to deviations from therapeutic targets and, especially if the
Publikováno v:
International Journal of Cosmetic Science. 20:307-316
Increasing requirements for cruelty-free risk assessment in the cosmetic industry have led to the development of several alternative experimental evaluation strategies. Quantification of the potential dermal absorption of ingredients of cosmetic and
Autor:
Adam C. Watkinson, Valerie J James, Darren M. Green, Robert H Sands, Kenneth A. Walters, K.R. Brain
Publikováno v:
Maturitas. 29:189-195
Objective: Conventional oral oestrogen replacement therapy can relieve postmenopausal symptoms but is associated with undesirable side-effects which can be minimised by avoiding the fluctuating hormonal blood levels resulting from oral therapy and el
Autor:
D. Howes, V.J. James, Kenneth A. Walters, C. K Kelling, S. D. Gettings, Darren M. Green, W.E. Dressler, K.R. Brain, Adam C. Watkinson
Publikováno v:
Food and Chemical Toxicology. 35:705-712
The human skin penetration of N-nitroso-N-methyldodecylamine (NDOMA) from isopropyl myristate (IPM) and two vehicles representative of cosmetic/personal care formulations was determined in vitro. When applied as an infinite dose in IPM (1 microgram/m
Publikováno v:
Pharmaceutical research. 30(8)
The penetration of intact particles in the nanometer range (nanoparticles, [NP]) through human skin is a controversial topic, which has attracted much interest from both the pharmaceutical and the personal care industries. Concerns have also been rai
Practical drug development approaches presented by leading experts Designed to support the development of new, effective therapeutics, Topical and Transdermal Drug Delivery: Principles and Practice explains the principles underlying the field and the