Zobrazeno 1 - 10
of 25
pro vyhledávání: '"Adam C. Vandergriff"'
Autor:
Phuong-Uyen C. Dinh, Dipti Paudel, Hayden Brochu, Kristen D. Popowski, M. Cyndell Gracieux, Jhon Cores, Ke Huang, M. Taylor Hensley, Erin Harrell, Adam C. Vandergriff, Arianna K. George, Raina T. Barrio, Shiqi Hu, Tyler A. Allen, Kevin Blackburn, Thomas G. Caranasos, Xinxia Peng, Lauren V. Schnabel, Kenneth B. Adler, Leonard J. Lobo, Michael B. Goshe, Ke Cheng
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-14 (2020)
Idiopathic pulmonary fibrosis (IPF) is a fatal lung disease and adult lung spheroid cells have been shown to promote regeneration in animal models of IPF. Here the authors show that the secretome and exosomes of lung spheroid cells is effective as in
Externí odkaz:
https://doaj.org/article/4496cdf678834d70ba8a9b30f7098a55
Autor:
Phuong-Uyen C. Dinh, Jhon Cores, M. Taylor Hensley, Adam C. Vandergriff, Junnan Tang, Tyler A. Allen, Thomas G. Caranasos, Kenneth B. Adler, Leonard J. Lobo, Ke Cheng
Publikováno v:
Respiratory Research, Vol 18, Iss 1, Pp 1-11 (2017)
Abstract Background Resident stem and progenitor cells have been identified in the lung over the last decade, but isolation and culture of these cells remains a challenge. Thus, although these lung stem and progenitor cells provide an ideal source fo
Externí odkaz:
https://doaj.org/article/90078bab3ecc4613907357149fe38f77
Autor:
Junnan Tang, Deliang Shen, Thomas George Caranasos, Zegen Wang, Adam C. Vandergriff, Tyler A. Allen, Michael Taylor Hensley, Phuong-Uyen Dinh, Jhon Cores, Tao-Sheng Li, Jinying Zhang, Quancheng Kan, Ke Cheng
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-9 (2017)
Stem cells exert their beneficial effects through secretion of regenerative factors. Here, the authors take the membranes and secreted factors from cardiac stem cells and generate a synthetic cell-mimicking microparticle, which, on injection in a mou
Externí odkaz:
https://doaj.org/article/68e90f01537b4132b5e027e02c99e7f0
Autor:
Adam C. Vandergriff, James Bizetto Meira de Andrade, Junnan Tang, M. Taylor Hensley, Jorge A. Piedrahita, Thomas G. Caranasos, Ke Cheng
Publikováno v:
Stem Cells International, Vol 2015 (2015)
Despite the efficacy of cardiac stem cells (CSCs) for treatment of cardiomyopathies, there are many limitations to stem cell therapies. CSC-derived exosomes (CSC-XOs) have been shown to be responsible for a large portion of the regenerative effects o
Externí odkaz:
https://doaj.org/article/73a68703787049b88fdc4ac92b8377d3
Autor:
Dipti Paudel, Phuong-Uyen Dinh, Kenneth B. Adler, Tyler A. Allen, Kristen D. Popowski, M. Cyndell Gracieux, Lauren V. Schnabel, Ke Huang, Leonard J. Lobo, Raina T. Barrio, Kevin Blackburn, Erin Harrell, Thomas G. Caranasos, Hayden N. Brochu, Shiqi Hu, Michael B. Goshe, Xinxia Peng, Arianna George, M. Taylor Hensley, Ke Cheng, Adam C. Vandergriff, Jhon Cores
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-14 (2020)
Nature Communications
Nature Communications
Idiopathic pulmonary fibrosis (IPF) is a fatal and incurable form of interstitial lung disease in which persistent injury results in scar tissue formation. As fibrosis thickens, the lung tissue loses the ability to facilitate gas exchange and provide
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6c9caaf3c27857fb0ec2baaefdff7f44
https://doaj.org/article/4496cdf678834d70ba8a9b30f7098a55
https://doaj.org/article/4496cdf678834d70ba8a9b30f7098a55
Autor:
Teng Su, Ke Huang, Hui Zhang, Shiqi Hu, Zhenhua Li, Adam C. Vandergriff, Qi Yin, Yongjun Li, Suyun Liu, Li Qiao, Jhon Cores, Ke Cheng, Junnan Tang, Hong Ma, Tyler A. Allen, Phuong-Uyen Dinh
Publikováno v:
Journal of Clinical Investigation. 129:2237-2250
Exosomes, as functional paracrine units of therapeutic cells, can partially reproduce the reparative properties of their parental cells. The constitution of exosomes, as well as their biological activity, largely depends on the cells that secrete the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::79b163ad3db23d0d45aafe5c4152a116
https://doi.org/10.1172/jci123135
https://doi.org/10.1172/jci123135
Autor:
Jhon Cores, Zegen Wang, Leonard J. Lobo, Jinying Zhang, Michael Taylor Hensley, Laura Ruterbories, Phuong-Uyen Dinh, Erin P. Sproul, Ke Cheng, Tao-Sheng Li, Tyler A. Allen, Adam C. Vandergriff, Junnan Tang, Zhen Gu, Alex M. Lynch, Ke Huang, George A. Stouffer, Deliang Shen, Thomas G. Caranasos, Ashley C. Brown, Teng Su, Emily Mihalko
Publikováno v:
Nature Biomedical Engineering. 2:17-26
Stem cell transplantation, as used clinically, suffers from low retention and engraftment of the transplanted cells. Inspired by the ability of platelets to recruit stem cells to sites of injury on blood vessels, we hypothesized that platelets might
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::09c7f794c54a78f7d37af3358e145af5
https://doi.org/10.1038/s41551-017-0182-x
https://doi.org/10.1038/s41551-017-0182-x
Autor:
Ke Huang, Adam C. Vandergriff, Li Qian, Michael Taylor Hensley, Shiqi Hu, Ke Cheng, Deliang Shen, Thomas G. Caranasos
Publikováno v:
Theranostics
Rationale: Cardiac stem cell-derived exosomes have been demonstrated to promote cardiac regeneration following myocardial infarction in preclinical studies. Recent studies have used intramyocardial injection in order to concentrate exosomes in the in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aadbaf819728f8676ec9e9ef8e91f273
https://doi.org/10.7150/thno.20524
https://doi.org/10.7150/thno.20524
Autor:
M. Taylor Hensley, Ke Cheng, Hu Zhang, Adam C. Vandergriff, Junnan Tang, Deliang Shen, Thomas G. Caranasos, Jinying Zhang, Xiaolin Cui, Yusak Hartanto
Publikováno v:
ACS Nano
Stem cell transplantation is currently implemented clinically but is limited by low retention and engraftment of transplanted cells and the adverse effects of inflammation and immunoreaction when allogeneic or xenogeneic cells are used. Here, we demo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c0aadfa0adfcb7f049ebfb41d0e1b9fe
https://doi.org/10.1021/acsnano.7b01008
https://doi.org/10.1021/acsnano.7b01008
Autor:
Jianhua Liu, Phuong-Uyen Dinh, Tyler A. Allen, Leonard J. Lobo, M. Taylor Hensley, S. Michaela Rikard, Yazhou Li, Yuepeng Chi, Junnan Tang, Kathryn Kinlaw, Dipti Paudel, Ke Cheng, Bo Niu, Adam C. Vandergriff, Thomas G. Caranasos, Jhon Cores
Publikováno v:
Stem Cells Translational Medicine
Idiopathic pulmonary fibrosis is a devastating interstitial lung disease characterized by the relentless deposition of extracellular matrix causing lung distortions and dysfunctions. The prognosis after detection is merely 3–5 years and the only tw
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ead4113b9dc5499d900b44bdde053f60
https://doi.org/10.1002/sctm.16-0374
https://doi.org/10.1002/sctm.16-0374