Výsledky vyhledávání - "Adam C. Glass"

Akademický článek

A Simple and Mild Microwave-Based Synthesis of Novel Functionalized Benzofulvenes

Autor: Adam C. Glass, Katherine E. Caspary, Cole Fisher, Connor Whyte, James Okubo, Lev N. Zakharov

Publikováno v: SynOpen, Vol 02, Iss 03, Pp 0256-0262 (2018)

Abstract Benzofulvenes and their derivatives are useful molecular entities having applications as biologically active molecules, polymer precursors, and optoelectronic devices. We have developed a simple and mild synthetic method for the formulation

Externí odkaz: https://doaj.org/article/3bdfc6c9741e4d2da487614970bb26e2

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A Simple and Mild Microwave-Based Synthesis of Novel Functionalized Benzofulvenes

Autor: Cole Fisher, Connor Whyte, James Okubo, Adam C. Glass, Lev N. Zakharov, Katherine E. Caspary

Publikováno v: SynOpen, Vol 02, Iss 03, Pp 0256-0262 (2018)

Benzofulvenes and their derivatives are useful molecular entities having applications as biologically active molecules, polymer precursors, and optoelectronic devices. We have developed a simple and mild synthetic method for the formulation of a vari

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d4a31ce2e6a3223b9519eb00522b99fe
https://doi.org/10.1055/s-0037-1610366

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Structural Characterization and Computer-Aided Optimization of a Small-Molecule Inhibitor of the Arp2/3 Complex, a Key Regulator of the Actin Cytoskeleton

Autor: Adam C. Glass, Shih-Yuan Liu, Zoe Cournia, Min Suk Han, Brad J. Nolen, George Patargias, Andrew W. Baggett

Publikováno v: ChemMedChem. 7:1286-1294

CK-666 (1) is a recently discovered small-molecule inhibitor of the actin-related protein 2/3 (Arp2/3) complex, a key actin cytoskeleton regulator with roles in bacterial pathogenesis and cancer cell motility. Although 1 is commercially available, th

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::19611abb2829ce1abbe119d207bcf92a
https://doi.org/10.1002/cmdc.201200104

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Pushing the limits of steric demand around a biaryl axis: synthesis of tetra-ortho-substituted biaryl naphthalenes

Autor: Sam Klonoski, Adam C. Glass, Lev N. Zakharov, Shih-Yuan Liu

Publikováno v: Chem. Commun.. 47:286-288

The synthesis of tetra-ortho-substituted biaryl naphthalenes, including examples bearing multiple ortho-isopropyl groups, has been developed via a catalytic rearrangement process.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e9c845b6700a38197aefb051abec4864
https://doi.org/10.1039/c0cc02170a

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Synthesis of Substituted Naphthalenes via a Catalytic Ring-Expansion Rearrangement

Autor: Shih-Yuan Liu, Adam C. Glass, Lev N. Zakharov, Benjamin B. Morris

Publikováno v: Organic Letters. 10:4855-4857

A new methodology for the preparation of substituted naphthalenes starting from readily available indenones, organometal reagents, and trimethylsilyldiazomethane via a catalytic rearrangement process is described. Hindered biaryl naphthalenes, includ

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::db3028495356097ab330cc0d8a505cba
https://doi.org/10.1021/ol8019617

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ChemInform Abstract: Pushing the Limits of Steric Demand Around a Biaryl Axis: Synthesis of Tetra-ortho-Substituted Biaryl Naphthalenes

Autor: Shih-Yuan Liu, Adam C. Glass, Lev N. Zakharov, Sam Klonoski

Publikováno v: ChemInform. 42

The reaction of cyclopropyl ketones (I) with aryllithium reagents followed by europium-catalyzed rearrangement gives rise to title “biaryl” naphthalenes (IV).

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::7307c252e2781843debe8c50c78e3727
https://doi.org/10.1002/chin.201115101

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