Zobrazeno 1 - 10
of 250
pro vyhledávání: '"Adam C Sedgwick"'
Autor:
Sophie A. Twigger, Blanca Dominguez, Vanesa Porto, Lina Hacker, Anthony J. Chalmers, Ross Breckenridge, Martin Treder, Adam C. Sedgwick, Fernando Dominguez, Ester M. Hammond
Publikováno v:
Redox Biology, Vol 76, Iss , Pp 103326- (2024)
Regions of hypoxia occur in most solid tumours and are known to significantly impact therapy response and patient prognosis. Ag5 is a recently reported silver molecular cluster which inhibits both glutathione and thioredoxin signalling therefore limi
Externí odkaz:
https://doaj.org/article/67a59339aad4476cbe985cd7a0f974ef
Fluorescent chemosensors have been widely applied in many diverse fields such as biology, physiology, pharmacology, and environmental sciences. The interdisciplinary nature of chemosensor research has continued to grow over the last 25 years to meet
Publikováno v:
Results in Chemistry, Vol 7, Iss , Pp 101244- (2024)
Superoxide anion is a highly reactive ROS however the sensing of this species is relatively unexplored. The current methods to sense superoxide requires the construction of complex probes which are often hard to synthesize. With this research we repo
Externí odkaz:
https://doaj.org/article/1e0f941d820a42bd8fae5812fc34790c
Autor:
Cherie C.Y. Wong, Jason L. Raymond, Lillian N. Usadi, Zhiyuan Zong, Stephanie C. Walton, Adam C. Sedgwick, James Kwan
Publikováno v:
Ultrasonics Sonochemistry, Vol 99, Iss , Pp 106559- (2023)
Sonochemistry is the use of ultrasound to generate highly reactive radical species through the inertial collapse of a gas/vapour cavity and is a green alternative for hydrogen production, wastewater treatment, and chemical synthesis and modifications
Externí odkaz:
https://doaj.org/article/0fc92ea702e7432faf9809f6ef8bb084
Autor:
Yunjie Xu, Yingwei Wang, Jusung An, Adam C. Sedgwick, Mingle Li, Jianlei Xie, Weibin Hu, Jianlong Kang, Sajal Sen, Axel Steinbrueck, Bin Zhang, Lijun Qiao, Swelm Wageh, Jonathan F. Arambula, Liping Liu, Han Zhang, Jonathan L. Sessler, Jong Seung Kim
Publikováno v:
Bioactive Materials, Vol 14, Iss , Pp 76-85 (2022)
An increased demand for iron is a hallmark of cancer cells and is thought necessary to promote high cell proliferation, tumor progression and metastasis. This makes iron metabolism an attractive therapeutic target. Unfortunately, current iron-based t
Externí odkaz:
https://doaj.org/article/d782771aa4954029b1ade144caa4c826
Autor:
Hai-Hao Han, Han-Min Wang, Paramesh Jangili, Mingle Li, Luling Wu, Yi Zang, Adam C. Sedgwick, Jia Li, Xiao-Peng He, Tony D. James, Jong Seung Kim
Publikováno v:
Chemical Society Reviews. 52:879-920
This tutorial review provides a general overview for the design of prodrugs and activatable phototherapeutics which enables the development of improved therapies.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3130ad76d584aced8431baedfff684d2
https://doi.org/10.1039/d2cs00673a
https://doi.org/10.1039/d2cs00673a
Autor:
Wen-Qi Meng, Adam C. Sedgwick, Nahyun Kwon, Mingxue Sun, Kai Xiao, Xiao-Peng He, Eric V. Anslyn, Tony D. James, Juyoung Yoon
Publikováno v:
Chemical Society Reviews. 52:601-662
Chemical warfare agents (CWAs) are toxic chemicals that have been intentionally developed for targeted and deadly use on humans. Although intended for military targets, the use of CWAs more often than not results in mass civilian casualties. To preve
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::effdea334b60327e6a1849ced27865ff
https://doi.org/10.1039/d2cs00650b
https://doi.org/10.1039/d2cs00650b
Autor:
Zhiyuan Jia, Hai-Hao Han, Adam C. Sedgwick, George T. Williams, Lauren Gwynne, James T. Brewster, Steven D. Bull, A. Toby A. Jenkins, Xiao-Peng He, Holger Schönherr, Jonathan L. Sessler, Tony D. James
Publikováno v:
Frontiers in Chemistry, Vol 8 (2020)
Here, we report a new pentafluoropropanamido rhodamine fluorescent probe (ACS-HNE) that allows for the selective detection of neutrophil elastase (NE). ACS-HNE displayed high sensitivity, with a low limit of detection (
Externí odkaz:
https://doaj.org/article/a1278cfa6415454d85fd337a0bb33517
Autor:
Axel Steinbrueck, James T. Brewster, II, Michael Y. Zhao, Adam C. Sedgwick, Jonathan L. Sessler
Publikováno v:
Results in Chemistry, Vol 2, Iss , Pp 100075- (2020)
Herein, we describe a detailed preparation of the versatile pyrrole building block 3,4-diethylpyrrole-2-carboxylate (1), a key structural feature in various porphyrins, porphyrinoids, and other chromophores. 1 was prepared via a one-pot DBU catalyzed
Externí odkaz:
https://doaj.org/article/ca12254ef6074873949bb4cd2a51a823
Autor:
Luling Wu, Xue Tian, Hai‐Hao Han, Jie Wang, Robin R. Groleau, Paramabhorn Tosuwan, Dr. Boontana Wannalerse, Dr. Adam C. Sedgwick, Prof. Steven D. Bull, Prof. Xiao‐Peng He, Prof. Tony D. James
Publikováno v:
ChemistryOpen, Vol 8, Iss 12, Pp 1407-1409 (2019)
Abstract Herein, we report the evaluation and synthesis of a reaction based fluorescent probe DCM‐Bpin for the detection of Peroxynitrite (ONOO−). DCM‐Bpin exhibits selective fluorescence off‐on response for ONOO− over other reactive oxygen
Externí odkaz:
https://doaj.org/article/8ec7365cf8da4036b848706869480a4c