Zobrazeno 1 - 10
of 39
pro vyhledávání: '"Adam C Mueller"'
Autor:
Eric T Clambey, Jacob Gadwa, Thomas E Bickett, Laurel B Darragh, Shilpa Bhatia, Miles Piper, Benjamin Van Court, Shiv Bhuvane, Diemmy Nguyen, Varuna Nangia, Sana D Karam, Michael W Knitz, Ayman J Oweida, Adam C Mueller, Douglas G Osborne, Xiyuan Bai, Sarah E Ferrara, Mary-Keara Boss, Andrew Goodspeed, Matthew A Burchill, Beth A Jirón Tamburini, Edward D Chan, Curtis R Pickering
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 9, Iss 4 (2021)
Background Numerous trials combining radiation therapy (RT) and immunotherapy in head and neck squamous cell carcinoma (HNSCC) are failing. Using preclinical immune cold models of HNSCC resistant to RT-immune checkpoint inhibitors, we investigate the
Externí odkaz:
https://doaj.org/article/cbf79a9cbfcd4744b19d4b8a1b088264
Autor:
Spencer J. Poiset, Sophia Shah, Louis Cappelli, Pramila Anné, Karen E. Mooney, Maria Werner-Wasik, Talya S. Laufer, James A. Posey, Daniel Lin, Atrayee Basu Mallick, Harish Lavu, Babar Bashir, Charles J. Yeo, Adam C. Mueller
Publikováno v:
Radiation Oncology, Vol 19, Iss 1, Pp 1-7 (2024)
Abstract Background Local treatment options for locally recurrent pancreatic adenocarcinoma (LR-PAC) are limited, with median survival time (MST) of 9–13 months (mos) following recurrence. MRI-guided stereotactic body radiation therapy (MRgSBRT) pr
Externí odkaz:
https://doaj.org/article/375cd634a0b34e7a99deed34febbadf2
Autor:
Parag Jitendra Parikh, Percy Lee, Daniel A. Low, Joshua Kim, Kathryn E. Mittauer, Michael F Bassetti, Carri K. Glide-Hurst, Ann C. Raldow, Yingli Yang, Lorraine Portelance, Kyle R. Padgett, Bassem Zaki, Rongxiao Zhang, Hyun Kim, Lauren E. Henke, Alex T. Price, Joseph D. Mancias, Christopher L. Williams, John Ng, Ryan Pennell, M. Raphael Pfeffer, Daphne Levin, Adam C. Mueller, Karen E. Mooney, Patrick Kelly, Amish P. Shah, Luca Boldrini, Lorenzo Placidi, Martin Fuss, Michael D. Chuong
Publikováno v:
International Journal of Radiation Oncology*Biology*Physics.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::86ae42ebc0746cd70820d20ac972d817
https://doi.org/10.1016/j.ijrobp.2023.05.023
https://doi.org/10.1016/j.ijrobp.2023.05.023
Autor:
Sana D. Karam, Elena B. Pasquale, Eric T. Clambey, Antonio Jimeno, Xiao-Jing Wang, Natalie J. Serkova, David Raben, Benjamin Van Court, Adam C. Mueller, Andy V. Phan, Dallin Milner, Laurel B. Darragh, Shelby Lennon, Ayman Oweida, Shilpa Bhatia
Mice implanted with PDX tumors show significantly reduced uptake of supra-paramagnetic iron oxide nanoparticles (SPIO) in the combined sEphB4-HSA and RT group compared to the groups treated with RT alone or with sEphB4-HSA alone in DCE-MRI imaging (A
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f40e96ae3a2c0a71d4425ecd0cdc09bd
https://doi.org/10.1158/0008-5472.22418520.v1
https://doi.org/10.1158/0008-5472.22418520.v1
Autor:
Sana D. Karam, Elena B. Pasquale, Eric T. Clambey, Antonio Jimeno, Xiao-Jing Wang, Natalie J. Serkova, David Raben, Benjamin Van Court, Adam C. Mueller, Andy V. Phan, Dallin Milner, Laurel B. Darragh, Shelby Lennon, Ayman Oweida, Shilpa Bhatia
Immunofluorescence staining showing co-expression of EphB4 and pan-keratin in Ly2 tumors.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9472c5e39fe6656ff7396b0c200fd318
https://doi.org/10.1158/0008-5472.22418541
https://doi.org/10.1158/0008-5472.22418541
Autor:
Sana D. Karam, Elena B. Pasquale, Eric T. Clambey, Antonio Jimeno, Xiao-Jing Wang, Natalie J. Serkova, David Raben, Benjamin Van Court, Adam C. Mueller, Andy V. Phan, Dallin Milner, Laurel B. Darragh, Shelby Lennon, Ayman Oweida, Shilpa Bhatia
IHC staining confirming expression of ephrin-B2 in areas stained with fibroblast-expressing α-Smooth muscle actin (α-SMA)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::67afcb005592eb6d766d5fd4291f1515
https://doi.org/10.1158/0008-5472.22418538.v1
https://doi.org/10.1158/0008-5472.22418538.v1
Autor:
Sana D. Karam, Elena B. Pasquale, Eric T. Clambey, Antonio Jimeno, Xiao-Jing Wang, Natalie J. Serkova, David Raben, Benjamin Van Court, Adam C. Mueller, Andy V. Phan, Dallin Milner, Laurel B. Darragh, Shelby Lennon, Ayman Oweida, Shilpa Bhatia
Blockade of EphB4-ephrin-B2 interaction combined with RT suppresses tumor growth in HNSCC tumors
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::580152e3bfb523bc3b498a5942f601c4
https://doi.org/10.1158/0008-5472.22418523
https://doi.org/10.1158/0008-5472.22418523
Autor:
Sana D. Karam, Elena B. Pasquale, Eric T. Clambey, Antonio Jimeno, Xiao-Jing Wang, Natalie J. Serkova, David Raben, Benjamin Van Court, Adam C. Mueller, Andy V. Phan, Dallin Milner, Laurel B. Darragh, Shelby Lennon, Ayman Oweida, Shilpa Bhatia
(A) ELISA assay measuring the concentration of TNYL-RAW-Fc protein in plasma 7 days after hydrodynamic injection of the TNYL-RAW-Fc plasmid. Data represent mean {plus minus} SD from measurements using different mice (n=2). (B) Inhibition of EphB4-eph
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::53170a91cb748ecd1e8c5e25959956ae
https://doi.org/10.1158/0008-5472.22418532
https://doi.org/10.1158/0008-5472.22418532
Autor:
Sana D. Karam, Elena B. Pasquale, Eric T. Clambey, Antonio Jimeno, Xiao-Jing Wang, Natalie J. Serkova, David Raben, Benjamin Van Court, Adam C. Mueller, Andy V. Phan, Dallin Milner, Laurel B. Darragh, Shelby Lennon, Ayman Oweida, Shilpa Bhatia
qPCR analysis shows elevated expression of EphB4 on intratumoral macrophages harvested from Ly2 tumors compared to ephrin-B2.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::30d61a658c40cfb9d8421fb4eaa73f30
https://doi.org/10.1158/0008-5472.22418535.v1
https://doi.org/10.1158/0008-5472.22418535.v1
Autor:
Sana D. Karam, Elena B. Pasquale, Eric T. Clambey, Antonio Jimeno, Xiao-Jing Wang, Natalie J. Serkova, David Raben, Benjamin Van Court, Adam C. Mueller, Andy V. Phan, Dallin Milner, Laurel B. Darragh, Shelby Lennon, Ayman Oweida, Shilpa Bhatia
Systemic depletion of CD8+ T cells results in increased tumor growth in Ly2 tumors treated with TNYL-RAW-Fc (A). Confirmation of CD8+ T cell depletion by flow cytometry (B). Student's t-test or one-way ANOVA was used to calculate the significance of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3265c2455c11f52d7950450a6b676adf
https://doi.org/10.1158/0008-5472.22418529
https://doi.org/10.1158/0008-5472.22418529