Zobrazeno 1 - 10
of 120
pro vyhledávání: '"Adam C Gower"'
Autor:
Darlene Lu, Serkalem Demissie, Nina B Horowitz, Adam C Gower, Marc E Lenburg, Yuriy O Alekseyev, Amira I Hussein, Beth Bragdon, Yu Liu, Dana Daukss, Jack M Page, Micheal Z Webster, Jennifer J Schlezinger, Elise F Morgan, Louis C Gerstenfeld
Publikováno v:
JBMR Plus, Vol 6, Iss 2, Pp n/a-n/a (2022)
ABSTRACT Time is a central element of the sexual dimorphic patterns of development, pathology, and aging of the skeleton. Because the transcriptome is a representation of the phenome, we hypothesized that both sex and sex‐specific temporal, transcr
Externí odkaz:
https://doaj.org/article/a34c5394e9f64112932106542a502aee
Autor:
Gang Liu, Asaf Maoz, Christopher Stevenson, Mary E Reid, Avrum Spira, Marc E Lenburg, Joshua D Campbell, Carter Merenstein, Yusuke Koga, Austin Potter, Adam C Gower, Sherry Zhang, Hanqiao Liu, Sarah A Mazzilli, Jennifer Beane
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 9, Iss 9 (2021)
Externí odkaz:
https://doaj.org/article/1a370bde366f4973b623356a8d390ced
Autor:
Deniz Koyuncu, Muhammad Khalid Khan Niazi, Thomas Tavolara, Claudia Abeijon, Melanie L Ginese, Yanghui Liao, Carolyn Mark, Aubrey Specht, Adam C Gower, Blanca I Restrepo, Daniel M Gatti, Igor Kramnik, Metin Gurcan, Bülent Yener, Gillian Beamer
Publikováno v:
PLoS Pathogens, Vol 17, Iss 8, p e1009773 (2021)
More humans have died of tuberculosis (TB) than any other infectious disease and millions still die each year. Experts advocate for blood-based, serum protein biomarkers to help diagnose TB, which afflicts millions of people in high-burden countries.
Externí odkaz:
https://doaj.org/article/6791769b2d6943c1ae030343c587d806
Publikováno v:
PLoS ONE, Vol 14, Iss 5, p e0216795 (2019)
The genetic programs responsible for pulmonary lymphatic maturation prior to birth are not known. To address this gap in knowledge, we developed a novel cell sorting strategy to collect fetal pulmonary lymphatic endothelial cells (PLECs) for global t
Externí odkaz:
https://doaj.org/article/47b5dc5b1ff54f2b8a8e86fb6b75ac36
Autor:
Aleksander D Szymaniak, Rongjuan Mi, Shannon E McCarthy, Adam C Gower, Taylor L Reynolds, Michael Mingueneau, Maria Kukuruzinska, Xaralabos Varelas
Publikováno v:
eLife, Vol 6 (2017)
Salivary glands, such as submandibular glands (SMGs), are composed of branched epithelial ductal networks that terminate in acini that together produce, transport and secrete saliva. Here, we show that the transcriptional regulator Yap, a key effecto
Externí odkaz:
https://doaj.org/article/d03c769aeff5471ca06c99db7e6a4e4a
Autor:
Elyse Kozlowski, Gregory A Wasserman, Marcos Morgan, Dónal O'Carroll, Nora-Guadalupe P Ramirez, Suryaram Gummuluru, Jasmine Y Rah, Adam C Gower, Michael Ieong, Lee J Quinton, Joseph P Mizgerd, Matthew R Jones
Publikováno v:
PLoS ONE, Vol 12, Iss 6, p e0179797 (2017)
Alveolar macrophages orchestrate pulmonary innate immunity and are essential for early immune surveillance and clearance of microorganisms in the airways. Inflammatory signaling must be sufficiently robust to promote host defense but limited enough t
Externí odkaz:
https://doaj.org/article/1b2675be230c4b7187e7e112a5852c34
Autor:
Arjun Guha, Michelle Vasconcelos, Rui Zhao, Adam C Gower, Jayaraj Rajagopal, Wellington V Cardoso
Publikováno v:
PLoS ONE, Vol 9, Iss 2, p e88848 (2014)
Clara cells (CCs) are a morphologically and operationally heterogeneous population of Secretoglobin Scgb1a1-expressing secretory cells that are crucial for airway homeostasis and post-injury repair. Analysis of the extent and origin of CC diversity a
Externí odkaz:
https://doaj.org/article/c5acb077ee6d43ad83b40c6aa2ae7036
Autor:
Jean-Bosco Tagne, Sumeet Gupta, Adam C Gower, Steven S Shen, Saaket Varma, Meenakshi Lakshminarayanan, Yuxia Cao, Avrum Spira, Thomas L Volkert, Maria I Ramirez
Publikováno v:
PLoS ONE, Vol 7, Iss 1, p e29907 (2012)
The homeodomain transcription factor Nkx2-1 is essential for normal lung development and homeostasis. In lung tumors, it is considered a lineage survival oncogene and prognostic factor depending on its expression levels. The target genes directly bou
Externí odkaz:
https://doaj.org/article/2172cd6095784208b075524b659956a1
Autor:
Kristen N Bushell, Susan E Leeman, Earl Gillespie, Adam C Gower, Karen L Reed, Arthur F Stucchi, James M Becker, Salomon Amar
Publikováno v:
PLoS ONE, Vol 6, Iss 9, p e25849 (2011)
Dysregulation of TNF-α in lamina propria macrophages (LPM) is a feature of inflammatory bowel diseases (IBD). LPS-Induced-TNF-Alpha-Factor (LITAF) is a transcription factor that mediates TNF-α expression. To determine whether LITAF participates in
Externí odkaz:
https://doaj.org/article/b0d9704075ac41869f71ced755a1dd7a
Autor:
Sachiko T. Homma, Xingyu Wang, Justin J. Frere, Adam C. Gower, Jingsong Zhou, Jean K. Lim, Benjamin R. tenOever, Lan Zhou
Publikováno v:
Biomedicines, Vol 12, Iss 7, p 1443 (2024)
Muscle fatigue represents the most prevalent symptom of long-term COVID, with elusive pathogenic mechanisms. We performed a longitudinal study to characterize histopathological and transcriptional changes in skeletal muscle in a hamster model of resp
Externí odkaz:
https://doaj.org/article/75ddaa28d7c4458b8ac017ea6241bab5