Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Adam C Frank"'
Publikováno v:
JMIR Mental Health, Vol 10, p e45572 (2023)
BackgroundSmartphones and wearable biosensors can continuously and passively measure aspects of behavior and physiology while also collecting data that require user input. These devices can potentially be used to monitor symptom burden; estimate diag
Externí odkaz:
https://doaj.org/article/f3203dfaf83842969947e43c6551e357
Publikováno v:
Journal of Clinical and Translational Science, Vol 7, Pp 106-106 (2023)
OBJECTIVES/GOALS: This study will collect multimodal and longitudinal data in adults with obsessive-compulsive disorder and healthy controls. A mixed effects random forest machine learning approach will be taken to develop a model that can predict in
Externí odkaz:
https://doaj.org/article/986cfb8d37684d7690d7abe85f66796f
Autor:
Adam C Frank
Publikováno v:
Frontiers in Systems Neuroscience, Vol 8 (2014)
Molecular and electrophysiological studies find convergent evidence suggesting that plasticity within a dendritic tree is not randomly dispersed, but rather clustered into functional groups. Further, results from in silico neuronal modeling show that
Externí odkaz:
https://doaj.org/article/30fb4ddbf5a0492497b33b3a5c8bd316
Autor:
Adam C. Frank, Katherine W. Scangos, Paul S. Larson, Tenzin Norbu, Anthony T. Lee, A Moses Lee
Publikováno v:
Brain Stimulation, Vol 14, Iss 4, Pp 1002-1004 (2021)
Externí odkaz:
https://doaj.org/article/2e47c69fa3684d95840617fd28dc8eaf
Autor:
Adam C. Frank, Shan Huang, Miou Zhou, Amos Gdalyahu, George Kastellakis, Tawnie K. Silva, Elaine Lu, Ximiao Wen, Panayiota Poirazi, Joshua T. Trachtenberg, Alcino J. Silva
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-11 (2018)
Structural remodeling of dendritic spines is thought to be a mechanism of memory storage. Here, the authors look at how spine turnover and clustering predict future learning and memory performance, and see that a genetically modified mouse with enhan
Externí odkaz:
https://doaj.org/article/9812b8e6055c436ab27e845c4f6d0c38
Autor:
Tenzin Norbu, A Moses Lee, Paul S. Larson, Anthony T. Lee, Katherine W. Scangos, Adam C Frank
Publikováno v:
Brain Stimul
Brain Stimulation, Vol 14, Iss 4, Pp 1002-1004 (2021)
Brain Stimulation, Vol 14, Iss 4, Pp 1002-1004 (2021)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b1a18b213c25ada1d7be338534cb19b6
https://pubmed.ncbi.nlm.nih.gov/34175247
https://pubmed.ncbi.nlm.nih.gov/34175247
Autor:
Miou Zhou, Panayiota Poirazi, Shan Huang, Amos Gdalyahu, Tawnie K. Silva, Ximiao Wen, Adam C. Frank, Elaine Lu, George Kastellakis, Alcino J. Silva, Joshua T. Trachtenberg
Publikováno v:
Nature communications, vol 9, iss 1
Nature Communications
Nature Communications, Vol 9, Iss 1, Pp 1-11 (2018)
Nature Communications
Nature Communications, Vol 9, Iss 1, Pp 1-11 (2018)
Modeling studies suggest that clustered structural plasticity of dendritic spines is an efficient mechanism of information storage in cortical circuits. However, why new clustered spines occur in specific locations and how their formation relates to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1290a0ca05b3589319f9c16b7f4a425d
https://escholarship.org/uc/item/38x007ch
https://escholarship.org/uc/item/38x007ch
Autor:
Karolyn F. Buttle, Alicia M. Celotto, Wayne A. Van Voorhies, Adam C Frank, Steven W McGrath, Carmen A. Mannella, Michael J. Palladino, Tim Fergestad
Publikováno v:
The Journal of Neuroscience. 26:810-820
Mitochondrial encephalomyopathies are common and devastating multisystem genetic disorders characterized by neuromuscular dysfunction and tissue degeneration. Point mutations in the human mitochondrialATP6gene are known to cause several related mitoc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2f447cbec061cc8f79ed33392c9862f2
https://doi.org/10.1523/jneurosci.4162-05.2006
https://doi.org/10.1523/jneurosci.4162-05.2006
Autor:
Alcino J. Silva, Denise J. Cai, Thomas Rogerson, Manuel F. López-Aranda, Yoshitake Sano, Adam C. Frank, Justin L. Shobe
Publikováno v:
Nature reviews. Neuroscience, vol 15, iss 3
There is now compelling evidence that the allocation of memory to specific neurons (neuronal allocation) and synapses (synaptic allocation) in a neurocircuit is not random and that instead specific mechanisms, such as increases in neuronal excitabili
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bd667e43b2d3e521d50fa5f4d280427a
https://escholarship.org/uc/item/0994j7tf
https://escholarship.org/uc/item/0994j7tf
Heritable mutations, known as inborn errors of metabolism, cause numerous devastating human diseases, typically as a result of a deficiency in essential metabolic products or the accumulation of toxic intermediates. We have isolated a missense mutati
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::041dbc9c35dc55f42a33cde2416643ce
https://europepmc.org/articles/PMC1667072/
https://europepmc.org/articles/PMC1667072/