Zobrazeno 1 - 10
of 69
pro vyhledávání: '"Adam Bohr"'
Autor:
Sourav K Poddar, Kimberly Harmon, Bridget M Whelan, Niki Konstantinides, Adam Bohr, Elisabeth Geraghty
Publikováno v:
BMJ Open, Vol 14, Iss 4 (2024)
Objectives To examine non-sport- and sport-related concussion severity, clinical care frequency and delayed reporting in relation to recovery duration among collegiate athletes.Design Retrospective cohort study.Setting Pac-12 varsity collegiate athle
Externí odkaz:
https://doaj.org/article/1b294e56fd3046d29033e7359bc4290c
Publikováno v:
Asian Journal of Pharmaceutical Sciences, Vol 13, Iss 6, Pp 584-591 (2018)
Hypromellose acetate succinate (HPMCAS) microparticles containing the poorly-water soluble drug celecoxib (CEL) were prepared by electrospraying intended for oral drug delivery. Various solvent mixtures with different solubility for CEL and HPMCAS we
Externí odkaz:
https://doaj.org/article/dcd2421ca6e646929adc47f6f0727617
Autor:
Rayane S.C.M.Q. Antonino, Michael Ruggiero, Zihui Song, Thais Leite Nascimento, Eliana Martins Lima, Adam Bohr, Matthias Manne Knopp, Korbinian Löbmann
Publikováno v:
International Journal of Pharmaceutics: X, Vol 1, Iss , Pp - (2019)
In this study, a method is described to determine the monolayer loading capacity (MLC) of the drugs naproxen and ibuprofen, both having high recrystallization tendencies, in mesoporous silica (MS), a well known carrier that is able to stabilize the a
Externí odkaz:
https://doaj.org/article/edf1f204893a4b638c247b78b282a896
Autor:
Johan Boetker, Dhara Raijada, Johanna Aho, Milad Khorasani, Søren V. Søgaard, Lærke Arnfast, Adam Bohr, Magnus Edinger, Jorrit J. Water, Jukka Rantanen
Publikováno v:
Asian Journal of Pharmaceutical Sciences, Vol 11, Iss 4, Pp 492-499 (2016)
The increasing demand for personalized medicine necessitates the production of easily customizable dosage forms. As the number of possible dosage forms may scale toward infinity, their uniqueness requires a versatile production platform and numerical
Externí odkaz:
https://doaj.org/article/30b4f7be7c1b460ba9b3e55bea996bf9
Autor:
Adam Bohr, Thais Leite Nascimento, Necati Harmankaya, Johan Juhl Weisser, Yingya Wang, Holger Grohganz, Thomas Rades, Korbinian Löbmann
Publikováno v:
Molecules, Vol 24, Iss 2, p 266 (2019)
Many anti-cancer drugs are difficult to formulate into an oral dosage form because they are both poorly water-soluble and show poor permeability, the latter often as a result of being an intestinal efflux pump substrate. To obtain a more water-solubl
Externí odkaz:
https://doaj.org/article/ac7175a2a85f47c9a6df65b33d4fb214
Publikováno v:
Biomarker Insights, Vol 1, Pp 99-111 (2006)
Metallothionein (MT) is a highly conserved, low-molecular-weight, cysteine-rich protein that occurs in 4 isoforms (MT-I to MT-IV), of which MT-I+II are the major and best characterized proteins. This review will focus on mammalian MT-I+II and their f
Externí odkaz:
https://doaj.org/article/8d418bb3ffb34544948adfb198dc70ca
Publikováno v:
Pharmaceutics, Vol 9, Iss 1, p 1 (2016)
Chitosan-based nanogels have been widely applied as drug delivery vehicles. Spray-drying of said nanogels allows for the preparation of dry powder nano-embedded microparticles. In this work, chitosan-based nanogels composed of chitosan, alginate, and
Externí odkaz:
https://doaj.org/article/583bdf4980e94330aea8f02e9e8ed45c
Autor:
Andreas Vegge, Jacob Wainer, Joy Collins, Ellen Marie Straarup, Ley Mikkel Wennemoes Hvitfeld, Siddartha Tamang, Herskind Peter, Stephen T. Buckley, Rikke Kaae Kirk, Ulrik Lytt Rahbek, Keiko Ishida, Xiaoya Lu, Brian Mouridsen, Jespersen Mikkel Oliver, Mette Poulsen, Stefán B Gunnarsson, Frantisek Hubalek, Johannes Josef Fels, Jorrit Jeroen Water, Alison Hayward, Adam Bohr, Robert Langer, Giovanni Traverso, Abramson Alex G, Morten Revsgaard Frederiksen, Brian Jensen, Jesper Peter Windum, Niclas Roxhed
Publikováno v:
Nat Biotechnol
Oral administration provides a simple and non-invasive approach for drug delivery. However, due to poor absorption and swift enzymatic degradation in the gastrointestinal tract, a wide range of molecules must be parenterally injected to attain requir
Autor:
Necati Harmankaya, Moritz Beck-Broichsitter, Thais Leite Nascimento, Adam Bohr, Rayane S.C.M.Q. Antonino
Publikováno v:
Acta Biomaterialia. 113:210-216
Surface-eroding polymers are of significant interest for various applications in the field of controlled drug delivery. Poly(ethylene carbonate), as an example, offers little control over the rate of degradation and, thus, drug release, which usually
Publikováno v:
Li, Y, Li, M, Rantanen, J, Yang, M & Bohr, A 2022, ' Transformation of nanoparticles into compacts : A study on PLGA and celecoxib nanoparticles ', International Journal of Pharmaceutics, vol. 611, 121278 . https://doi.org/10.1016/j.ijpharm.2021.121278
Oral delivery of nanoparticles possesses many advantages for delivery of active pharmaceutical ingredients (APIs) to the gastrointestinal tract. However, the poor physical stability of nanoparticles in liquid state is often a challenge. Removing wate