Zobrazeno 1 - 10
of 41
pro vyhledávání: '"Adam Bohnert"'
Publikováno v:
Frontiers in Physiology, Vol 13 (2023)
Externí odkaz:
https://doaj.org/article/183f17b0f8f3429bb7773ee8607257f0
Autor:
K. Adam Bohnert, Alyssa E. Johnson
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 10 (2022)
Lysosomes are acidic, membrane-bound organelles that play essential roles in cellular quality control, metabolism, and signaling. The lysosomes of a cell are commonly depicted as vesicular organelles. Yet, lysosomes in fact show a high degree of ultr
Externí odkaz:
https://doaj.org/article/c67a877348ef40d2a0f3fbddaa2cfae2
Autor:
Madhuja Samaddar, Jérôme Goudeau, Melissa Sanchez, David H Hall, K Adam Bohnert, Maria Ingaramo, Cynthia Kenyon
Publikováno v:
eLife, Vol 10 (2021)
Somatic cells age and die, but the germ-cell lineage is immortal. In Caenorhabditis elegans, germline immortality involves proteostasis renewal at the beginning of each new generation, when oocyte maturation signals from sperm trigger the clearance o
Externí odkaz:
https://doaj.org/article/fc5f2a8480a34f0d98baf157cabd6769
Publikováno v:
bioRxiv
InSchizosaccharomyces pombeseptum formation is coordinated with cytokinetic ring constriction but the mechanisms linking these events are unclear. In this study, we explored the role of the cytokinetic ring component Fic1, first identified by its int
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::44be16a7ddca3d5a74c9d3b0f1bfd996
https://europepmc.org/articles/PMC10054984/
https://europepmc.org/articles/PMC10054984/
Autor:
K. Adam Bohnert, Tyler J. Butsch, Dominique A Dolese, Alyssa E. Johnson, Bhaswati Ghosh, Matthew P Junot
Publikováno v:
Autophagy. 18:1522-1533
Organelle-specific autophagy directs degradation of eukaryotic organelles under certain conditions. Like other organelles, peroxisomes are subject to autophagic turnover at lysosomes. However, peroxisome autophagy (pexophagy) has yet to be analyzed i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3b1724e1c93b277ed41c50197170586d
https://doi.org/10.1080/15548627.2021.1990647
https://doi.org/10.1080/15548627.2021.1990647
Valosin-containing protein (VCP) binds and extracts ubiquitinated cargo to regulate protein homeostasis. While VCP has been studied primarily in aging and disease contexts, it also affects germline development. However, the precise molecular function
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6338bce3f07cf531a80c1fe43f63a753
https://doi.org/10.1101/2022.12.21.521492
https://doi.org/10.1101/2022.12.21.521492
Publikováno v:
J Exp Biol
Sex-specific differences in animal behavior commonly reflect unique reproductive interests. In the nematode Caenorhabditis elegans, hermaphrodites can reproduce without a mate and thus prioritize feeding to satisfy the high energetic costs of reprodu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9e57f5b1f7b04b016077cd8af15a4c49
https://doi.org/10.1242/jeb.244282
https://doi.org/10.1242/jeb.244282
Autor:
Tyler J. Butsch, Suman Das, Eric D. Eymard, Brennan M. Mercola, Cara D. Ramos, Alyssa E. Johnson, K. Adam Bohnert, Tatiana V. Villalobos, Sanaa Alam, Bhaswati Ghosh
Dietary restriction promotes longevity via autophagy activation. However, changes to lysosomes underlying this effect remain unclear. Using the nematode Caenorhabditis elegans, we show that induction of autophagic tubular lysosomes, which occurs upon
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6e28edbf06483dd692c95d840eeb5d79
https://doi.org/10.1101/2021.10.28.466256
https://doi.org/10.1101/2021.10.28.466256
Autor:
Dominique A, Dolese, Matthew P, Junot, Bhaswati, Ghosh, Tyler J, Butsch, Alyssa E, Johnson, K Adam, Bohnert
Publikováno v:
Autophagy. 18(7)
Organelle-specific autophagy directs degradation of eukaryotic organelles under certain conditions. Like other organelles, peroxisomes are subject to autophagic turnover at lysosomes. However, peroxisome autophagy (pexophagy) has yet to be analyzed i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::4be7a6ae90983e98c6a8bb45a962a53d
https://pubmed.ncbi.nlm.nih.gov/34689720
https://pubmed.ncbi.nlm.nih.gov/34689720
Publikováno v:
Innovation in Aging. 6:130-130
Like other biological processes, aging is not random but subject to molecular control. Natural products that modify core metabolic parameters, including fat content, may provide entry points to extend animal lifespan and promote healthy aging. Here,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0ae7412a65fd80817935655d68a01830
https://doi.org/10.1093/geroni/igac059.521
https://doi.org/10.1093/geroni/igac059.521