Zobrazeno 1 - 10
of 31
pro vyhledávání: '"Adam Ben Shem"'
Publikováno v:
eLife, Vol 12 (2024)
Sirtuin 6 (SIRT6) is an NAD+-dependent histone H3 deacetylase that is prominently found associated with chromatin, attenuates transcriptionally active promoters and regulates DNA repair, metabolic homeostasis and lifespan. Unlike other sirtuins, it h
Externí odkaz:
https://doaj.org/article/1e6b6b06a7b744acbbeadc0ce34b2a17
Autor:
Grigory Sharov, Karine Voltz, Alexandre Durand, Olga Kolesnikova, Gabor Papai, Alexander G. Myasnikov, Annick Dejaegere, Adam Ben Shem, Patrick Schultz
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-7 (2017)
The transcription co-activator complex SAGA is recruited to promoters by transcriptional activators and promotes the formation of the pre-initiation complex. Here, the authors present the cryo-EM structure of the SAGA complex and resolve the major ta
Externí odkaz:
https://doaj.org/article/9840b937571446d3924b256fc336f3ee
Sirtuin 6 (SIRT6) is a NAD+ dependent histone H3 deacetylase that is prominently found associated with chromatin, attenuates transcriptionally active promoters and regulates DNA repair, metabolic homeostasis and life-span. Unlike other sirtuins it ha
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8b75cc841f7b4c4aa3189fc18467db4d
https://doi.org/10.1101/2023.03.20.533444
https://doi.org/10.1101/2023.03.20.533444
Autor:
Patrick Schultz, Alexandre Frechard, Rozalie Hexnerova, Corinne Crucifix, Gabor Papai, Ekaterina Smirnova, Celine Faux, Florie Ping, Dominique Helmlinger, Adam Ben-Shem
Histone acetylation regulates most DNA transactions and is dynamically controlled by highly conserved enzymes. The only essential histone acetyltransferase (HAT) in yeast, Esa1, is part of the 1MDa NuA4 complex, which plays pivotal roles in both tran
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5050b798d9ab7da7be76a5ca2569b095
https://doi.org/10.21203/rs.3.rs-1497616/v1
https://doi.org/10.21203/rs.3.rs-1497616/v1
Publikováno v:
FEBS Journal
FEBS Journal, 2021, 288 (10), pp.3135-3147. ⟨10.1111/febs.15563⟩
FEBS Journal, Wiley, 2020, ⟨10.1111/febs.15563⟩
FEBS Journal, 2021, 288 (10), pp.3135-3147. ⟨10.1111/febs.15563⟩
FEBS Journal, Wiley, 2020, ⟨10.1111/febs.15563⟩
International audience; In eukaryotes, transcription of protein encoding genes is initiated by the controlled deposition of the TATA-box binding protein TBP onto gene promoters, followed by the ordered assembly of a pre-initiation complex. The SAGA c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dde6ea28251246e55f2cbd720ae3f9c1
https://hal.science/hal-03454181/document
https://hal.science/hal-03454181/document
Publikováno v:
Nature Communications
Nature Communications, Nature Publishing Group, 2018, 9 (1), ⟨10.1038/s41467-018-07096-y⟩
Nature Communications, Vol 9, Iss 1, Pp 1-10 (2018)
Nature Communications, Nature Publishing Group, 2018, 9 (1), ⟨10.1038/s41467-018-07096-y⟩
Nature Communications, Vol 9, Iss 1, Pp 1-10 (2018)
Transcription preinitiation complex assembly on the promoters of protein encoding genes is nucleated in vivo by TFIID composed of the TATA-box Binding Protein (TBP) and 13 TBP-associate factors (Tafs) providing regulatory and chromatin binding functi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::db86831c87bd5af62a368201c2fdc33f
https://hal.archives-ouvertes.fr/hal-02342125/file/2018-kolesnikova.pdf
https://hal.archives-ouvertes.fr/hal-02342125/file/2018-kolesnikova.pdf
Autor:
Adam Ben Shem, Annick Dejaegere, Alexandre Durand, Patrick Schultz, Grigory Sharov, Gabor Papai, Alexander G. Myasnikov, Karine Voltz, Olga Kolesnikova
Publikováno v:
Nature Communications
Nature Communications, Nature Publishing Group, 2017, 8 (1), ⟨10.1038/s41467-017-01564-7⟩
Nature Communications, Vol 8, Iss 1, Pp 1-7 (2017)
Nature Communications, Nature Publishing Group, 2017, 8 (1), ⟨10.1038/s41467-017-01564-7⟩
Nature Communications, Vol 8, Iss 1, Pp 1-7 (2017)
The transcription co-activator complex SAGA is recruited to gene promoters by sequence-specific transcriptional activators and by chromatin modifications to promote pre-initiation complex formation. The yeast Tra1 subunit is the major target of acidi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5232d1bb0bc9691a371c19c4fb4b9839
https://hal.archives-ouvertes.fr/hal-03052620
https://hal.archives-ouvertes.fr/hal-03052620
Autor:
Nathan, Nelson1 nelson@post.tau.ac.il, Adam, Ben-Shem1
Publikováno v:
Nature Reviews Molecular Cell Biology. Oct2005, Vol. 6 Issue 10, p1-13. 13p. 9 Diagrams.
Publikováno v:
Science. 330:1203-1209
Macromolecular Message Translation The ribosome is a macromolecular machine that translates the sequence of messenger RNA into proteins in all living cells. Structures of prokaryotic ribosomes have supplied insight into the conserved features of such
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::79230d0186b0a13e08c2dca99997ee18
https://doi.org/10.1126/science.1194294
https://doi.org/10.1126/science.1194294
Publikováno v:
Proceedings of the National Academy of Sciences. 104:462-466
Intramembrane proteases catalyze peptide bond cleavage of integral membrane protein substrates. This activity is crucial for many biological and pathological processes. Rhomboids are evolutionarily widespread intramembrane serine proteases. Here, we
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1d6262a6dac8f7f0981d2620fe68afd7
https://doi.org/10.1073/pnas.0609773104
https://doi.org/10.1073/pnas.0609773104