Zobrazeno 1 - 10
of 33
pro vyhledávání: '"Adam Bartok"'
Autor:
Adam Bartok, David Weaver, Tünde Golenár, Zuzana Nichtova, Máté Katona, Száva Bánsághi, Kamil J. Alzayady, V. Kaye Thomas, Hideaki Ando, Katsuhiko Mikoshiba, Suresh K. Joseph, David I. Yule, György Csordás, György Hajnóczky
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-14 (2019)
Membrane contact sites between the ER and mitochondria are known to convey calcium signals between these two organelles via IP3 receptors, but the molecular mechanisms are currently unclear. Here, the authors show that IP3 receptors play a structural
Externí odkaz:
https://doaj.org/article/573c9a6e3c934f97817996bbe29c011b
Autor:
Melanie Paillard, György Csordás, Gergö Szanda, Tünde Golenár, Valentina Debattisti, Adam Bartok, Nadan Wang, Cynthia Moffat, Erin L. Seifert, András Spät, György Hajnóczky
Publikováno v:
Cell Reports, Vol 18, Iss 10, Pp 2291-2300 (2017)
Mitochondrial Ca2+ uptake through the Ca2+ uniporter supports cell functions, including oxidative metabolism, while meeting tissue-specific calcium signaling patterns and energy needs. The molecular mechanisms underlying tissue-specific control of th
Externí odkaz:
https://doaj.org/article/74bcc08031334f4fbefb96b73971341a
Autor:
Zoltan Varga, Tamás Juhász, Csaba Matta, János Fodor, Éva Katona, Adam Bartok, Tamás Oláh, Attila Sebe, László Csernoch, Gyorgy Panyi, Róza Zákány
Publikováno v:
PLoS ONE, Vol 6, Iss 11, p e27957 (2011)
BACKGROUND: Understanding the key elements of signaling of chondroprogenitor cells at the earliest steps of differentiation may substantially improve our opportunities for the application of mesenchymal stem cells in cartilage tissue engineering, whi
Externí odkaz:
https://doaj.org/article/6babc87752e34a91b0ed57e0520c7c9d
Autor:
Raghavendra Singh, Adam Bartok, Melanie Paillard, Ashley Tyburski, Melanie Elliott, György Hajnóczky
Publikováno v:
Science Advances
Science Advances, 2022, 8 (11), pp.eabj4716. ⟨10.1126/sciadv.abj4716⟩
Science Advances, 2022, 8 (11), pp.eabj4716. ⟨10.1126/sciadv.abj4716⟩
Dysregulation of mitochondrial Ca 2+ homeostasis has been linked to neurodegenerative diseases. Mitochondrial Ca 2+ uptake is mediated via the calcium uniporter complex that is primarily regulated by MICU1, a Ca 2+ -sensing gatekeeper. Recently, huma
Autor:
Adam Bartok, Laszlo Csanady
Publikováno v:
Biophysical Journal. 122:110a
Autor:
Ana Töpf, Joachim Weis, Artur Czech, Rita Horvath, Thomas Eggermann, Miriam Elbracht, Erik Freier, Katja Eggermann, György Hajnóczky, Adam Bartok, Hanns Lochmüller, Martin Häusler, Kai-Ting Huang, Claudia Groß, Vietxuan Phan, Nicolai Kohlschmidt, Andreas Roos, Stephanie Zippel
Funder: Ministerium für Innovation, Wissenschaft und Forschung des Landes Nordrhein‐Westfalen; Id: http://dx.doi.org/10.13039/501100009591
Funder: Bundesministerium für Bildung und Forschung; Id: http://dx.doi.org/10.13039/501100002347
Funder: Bundesministerium für Bildung und Forschung; Id: http://dx.doi.org/10.13039/501100002347
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3cc925a19c3d5a5d39058667389e8c61
Autor:
Suresh K. Joseph, György Csordás, Tünde Golenár, Katsuhiko Mikoshiba, György Hajnóczky, Zuzana Nichtova, V. Kaye Thomas, David I. Yule, Kamil J. Alzayady, David Weaver, Máté Katona, Hideaki Ando, Adam Bartok, Száva Bánsághi
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-14 (2019)
Contact sites of endoplasmic reticulum (ER) and mitochondria locally convey calcium signals between the IP3 receptors (IP3R) and the mitochondrial calcium uniporter, and are central to cell survival. It remains unclear whether IP3Rs also have a struc
Autor:
Adam Bartok, Laszlo Csanady
Publikováno v:
Biophysical Journal. 121:14a
Autor:
Pamela V, Martino Adami, Zuzana, Nichtová, David B, Weaver, Adam, Bartok, Thomas, Wisniewski, Drew R, Jones, Sonia, Do Carmo, Eduardo M, Castaño, A Claudio, Cuello, György, Hajnóczky, Laura, Morelli
Publikováno v:
J Cell Sci
The use of fixed fibroblasts from familial and sporadic Alzheimer's disease patients has previously indicated an upregulation of mitochondria–ER contacts (MERCs) as a hallmark of Alzheimer's disease. Despite its potential significance, the relevanc
Autor:
David Weaver, György Hajnóczky, Zuzana Nichtova, Laura Morelli, Eduardo M. Castaño, Pamela V. Martino Adami, Claudio Cuello, Adam Bartok, Drew R. Jones, Thomas Wisniewski, Sonia Do Carmo
Publikováno v:
Journal of Cell Science.
Reports using fixed fibroblasts from familial and sporadic Alzheimer's disease (AD) patients indicated upregulated mitochondria-endoplasmic reticulum contacts (MERC) as a hallmark of AD. Despite its potential significance, the relevance of these resu