Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Adam B. Fessler"'
Autor:
Shu-ta Wu, Anthony J. Fowler, Corey B. Garmon, Adam B. Fessler, Joshua D. Ogle, Kajal R. Grover, Bailey C. Allen, Chandra D. Williams, Ru Zhou, Mahboubeh Yazdanifar, Craig A. Ogle, Pinku Mukherjee
Publikováno v:
BMC Cancer, Vol 18, Iss 1, Pp 1-13 (2018)
Abstract Background Pancreatic ductal adenocarcinoma (PDA) remains the most aggressive cancers with a 5-year survival below 10%. Systemic delivery of chemotherapy drugs has severe side effects in patients with PDA and does not significantly improve o
Externí odkaz:
https://doaj.org/article/07bd40c201904f37a49e6060dca5f3bc
Publikováno v:
Bioconjugate Chemistry. 32:904-908
Isatoic anhydride (IA) has been shown to be a useful platform for quantifiable bioconjugation. The elaboration of a water-soluble isatoic anhydride-based platform with biotin offers readily quantifiable biotinylation reagents through nondestructive m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d8f125b1bae2a5a936577b1155a88771
https://doi.org/10.1021/acs.bioconjchem.1c00150
https://doi.org/10.1021/acs.bioconjchem.1c00150
Autor:
Abhishek Dey, Adam B. Fessler, Anthony J. Fowler, Craig A. Ogle, Dominic S. Finis, Kausik Chakrabarti
Publikováno v:
Bioconjugate Chemistry. 31:884-888
1-Methyl-7-nitroisatoic anhydride (1M7) and 2-methylnicotinic acid imidazolide (NAI) are two of the most commonly applied RNA-SHAPE electrophiles; 1M7 due to its high reactivity and NAI for its solubility and cell permeability. While the addition of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6a221ad926a7b3c91c5b3961242f5a5c
https://doi.org/10.1021/acs.bioconjchem.0c00024
https://doi.org/10.1021/acs.bioconjchem.0c00024
Publikováno v:
Nucleic Acids Research
Nucleic Acids Research, 49(6):e34. Oxford University Press
Nucleic Acids Research, 49(6):e34. Oxford University Press
Due to the mounting evidence that RNA structure plays a critical role in regulating almost any physiological as well as pathological process, being able to accurately define the folding of RNA molecules within living cells has become a crucial need.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7c74f16e0521848cca4df578c5d6484b
https://doi.org/10.1101/2020.08.31.274761
https://doi.org/10.1101/2020.08.31.274761
Autor:
Adam B. Fessler, Dominic S. Finis, Anthony J. Fowler, Nemah-Allah Saleh, Daniel S. Jones, Abhishek Dey, Kausik Chakrabarti, Corey B. Garmon, Craig A. Ogle
Publikováno v:
Bioconjugate Chemistry. 29:3196-3202
N-(3-Iodopropyl)isatoic anhydride (IPIA) has been demonstrated to serve as an efficient substrate for the development of an extended bioconjugation platform. Derivatives of IPIA are water-soluble and adaptable and share a common chromophore, renderin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e6b2f400cd1161ce3a279a69a7e311e2
https://doi.org/10.1021/acs.bioconjchem.8b00518
https://doi.org/10.1021/acs.bioconjchem.8b00518
Publikováno v:
Organic & Biomolecular Chemistry. 15:9599-9602
Isatoic anhydride is elaborated to water soluble bioconjugation reagents that gives functionality and water solubility in one self-cleaning step. This new platform offers high atom economy with carbon dioxide being the only byproduct, and is shown to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::14629be2c5fd81d668a19cbc1022a9dc
https://doi.org/10.1039/c7ob02377d
https://doi.org/10.1039/c7ob02377d
Autor:
Bailey C. Allen, Mahboubeh Yazdanifar, Chandra D. Williams, Joshua D. Ogle, Kajal Grover, Craig A. Ogle, Shu-ta Wu, Corey B. Garmon, Pinku Mukherjee, Adam B. Fessler, Anthony J. Fowler, Ru Zhou
Publikováno v:
BMC Cancer
BMC Cancer, Vol 18, Iss 1, Pp 1-13 (2018)
BMC Cancer, Vol 18, Iss 1, Pp 1-13 (2018)
Background Pancreatic ductal adenocarcinoma (PDA) remains the most aggressive cancers with a 5-year survival below 10%. Systemic delivery of chemotherapy drugs has severe side effects in patients with PDA and does not significantly improve overall su
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0be2f0d8cb2c1dab3609c2af8054731c
https://doi.org/10.1186/s12885-018-4393-7
https://doi.org/10.1186/s12885-018-4393-7