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pro vyhledávání: '"Adam B. Fessler"'
Autor:
Shu-ta Wu, Anthony J. Fowler, Corey B. Garmon, Adam B. Fessler, Joshua D. Ogle, Kajal R. Grover, Bailey C. Allen, Chandra D. Williams, Ru Zhou, Mahboubeh Yazdanifar, Craig A. Ogle, Pinku Mukherjee
Publikováno v:
BMC Cancer, Vol 18, Iss 1, Pp 1-13 (2018)
Abstract Background Pancreatic ductal adenocarcinoma (PDA) remains the most aggressive cancers with a 5-year survival below 10%. Systemic delivery of chemotherapy drugs has severe side effects in patients with PDA and does not significantly improve o
Externí odkaz:
https://doaj.org/article/07bd40c201904f37a49e6060dca5f3bc
Publikováno v:
Bioconjugate Chemistry. 32:904-908
Isatoic anhydride (IA) has been shown to be a useful platform for quantifiable bioconjugation. The elaboration of a water-soluble isatoic anhydride-based platform with biotin offers readily quantifiable biotinylation reagents through nondestructive m
Autor:
Abhishek Dey, Adam B. Fessler, Anthony J. Fowler, Craig A. Ogle, Dominic S. Finis, Kausik Chakrabarti
Publikováno v:
Bioconjugate Chemistry. 31:884-888
1-Methyl-7-nitroisatoic anhydride (1M7) and 2-methylnicotinic acid imidazolide (NAI) are two of the most commonly applied RNA-SHAPE electrophiles; 1M7 due to its high reactivity and NAI for its solubility and cell permeability. While the addition of
Publikováno v:
Nucleic Acids Research
Nucleic Acids Research, 49(6):e34. Oxford University Press
Nucleic Acids Research, 49(6):e34. Oxford University Press
Due to the mounting evidence that RNA structure plays a critical role in regulating almost any physiological as well as pathological process, being able to accurately define the folding of RNA molecules within living cells has become a crucial need.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7c74f16e0521848cca4df578c5d6484b
https://doi.org/10.1101/2020.08.31.274761
https://doi.org/10.1101/2020.08.31.274761
Autor:
Adam B. Fessler, Dominic S. Finis, Anthony J. Fowler, Nemah-Allah Saleh, Daniel S. Jones, Abhishek Dey, Kausik Chakrabarti, Corey B. Garmon, Craig A. Ogle
Publikováno v:
Bioconjugate Chemistry. 29:3196-3202
N-(3-Iodopropyl)isatoic anhydride (IPIA) has been demonstrated to serve as an efficient substrate for the development of an extended bioconjugation platform. Derivatives of IPIA are water-soluble and adaptable and share a common chromophore, renderin
Publikováno v:
Organic & Biomolecular Chemistry. 15:9599-9602
Isatoic anhydride is elaborated to water soluble bioconjugation reagents that gives functionality and water solubility in one self-cleaning step. This new platform offers high atom economy with carbon dioxide being the only byproduct, and is shown to
Autor:
Bailey C. Allen, Mahboubeh Yazdanifar, Chandra D. Williams, Joshua D. Ogle, Kajal Grover, Craig A. Ogle, Shu-ta Wu, Corey B. Garmon, Pinku Mukherjee, Adam B. Fessler, Anthony J. Fowler, Ru Zhou
Publikováno v:
BMC Cancer
BMC Cancer, Vol 18, Iss 1, Pp 1-13 (2018)
BMC Cancer, Vol 18, Iss 1, Pp 1-13 (2018)
Background Pancreatic ductal adenocarcinoma (PDA) remains the most aggressive cancers with a 5-year survival below 10%. Systemic delivery of chemotherapy drugs has severe side effects in patients with PDA and does not significantly improve overall su
Publikováno v:
Nucleic Acids Research; 4/6/2021, Vol. 49 Issue 6, pe34-e34, 1p