Zobrazeno 1 - 10
of 43
pro vyhledávání: '"Adam Alexander T. Smith"'
Autor:
Sartaj Ahmad Mir, Li Chen, Satvika Burugupalli, Bo Burla, Shanshan Ji, Adam Alexander T. Smith, Kothandaraman Narasimhan, Adaikalavan Ramasamy, Karen Mei-Ling Tan, Kevin Huynh, Corey Giles, Ding Mei, Gerard Wong, Fabian Yap, Kok Hian Tan, Fiona Collier, Richard Saffery, Peter Vuillermin, Anne K. Bendt, David Burgner, Anne-Louise Ponsonby, Yung Seng Lee, Yap Seng Chong, Peter D. Gluckman, Johan G. Eriksson, Peter J. Meikle, Markus R. Wenk, Neerja Karnani
Publikováno v:
BMC Medicine, Vol 20, Iss 1, Pp 1-18 (2022)
Abstract Background Lipids play a vital role in health and disease, but changes to their circulating levels and the link with obesity remain poorly characterized in expecting mothers and their offspring in early childhood. Methods LC-MS/MS-based quan
Externí odkaz:
https://doaj.org/article/2a524f4cbd2448029ad0b8261c9144bb
Autor:
Kevin Huynh, Wei Ling Florence Lim, Corey Giles, Kaushala S. Jayawardana, Agus Salim, Natalie A. Mellett, Adam Alexander T. Smith, Gavriel Olshansky, Brian G. Drew, Pratishtha Chatterjee, Ian Martins, Simon M. Laws, Ashley I. Bush, Christopher C. Rowe, Victor L. Villemagne, David Ames, Colin L. Masters, Matthias Arnold, Kwangsik Nho, Andrew J. Saykin, Rebecca Baillie, Xianlin Han, Rima Kaddurah-Daouk, Ralph N. Martins, Peter J. Meikle
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-11 (2020)
The onset and pathology of Alzheimer’s disease (AD) is associated with changes to lipid metabolism. Here, the authors analysed 569 lipids from 32 classes and subclasses in two independent patient cohorts to identify key lipid pathways to link the p
Externí odkaz:
https://doaj.org/article/4dd529924c75463b9ab9f71c074acad6
Autor:
Sudip Paul, Adam Alexander T. Smith, Kevin Culham, Kevin A. Gunawan, Jacqueline M. Weir, Michelle A. Cinel, Kaushala S. Jayawardana, Natalie A. Mellett, Man K.S. Lee, Andrew J. Murphy, Graeme I. Lancaster, Paul J. Nestel, Bronwyn A. Kingwell, Peter J. Meikle
Publikováno v:
Journal of Lipid Research, Vol 62, Iss , Pp 100092- (2021)
Plasmalogens are membrane glycerophospholipids with diverse biological functions. Reduced plasmalogen levels have been observed in metabolic diseases; hence, increasing their levels might be beneficial in ameliorating these conditions. Shark liver oi
Externí odkaz:
https://doaj.org/article/ebca859b244747eda6a5bfe2eb3bfd6d
Autor:
Habtamu B. Beyene, Gavriel Olshansky, Corey Giles, Kevin Huynh, Michelle Cinel, Natalie A. Mellett, Adam Alexander T. Smith, Jonathan E. Shaw, Dianna J. Magliano, Peter J. Meikle
Publikováno v:
Metabolites, Vol 11, Iss 9, p 646 (2021)
Lipid metabolism is tightly linked to adiposity. Comprehensive lipidomic profiling offers new insights into the dysregulation of lipid metabolism in relation to weight gain. Here, we investigated the relationship of the human plasma lipidome and chan
Externí odkaz:
https://doaj.org/article/d59a4998a48942b490fe5056ac25e8ae
Autor:
Sudip Paul, Aliki A. Rasmiena, Kevin Huynh, Adam Alexander T. Smith, Natalie A. Mellett, Karin Jandeleit-Dahm, Graeme I. Lancaster, Peter J. Meikle
Publikováno v:
Metabolites, Vol 11, Iss 5, p 299 (2021)
Plasmalogens or alkenylphospholipids are a sub-class of glycerophospholipids with numerous biological functions and are thought to have protective effects against metabolic disease. Dietary supplementation with alkylglycerols (AKGs) has been shown to
Externí odkaz:
https://doaj.org/article/7996790ac9e24e4d96c4cd1a94d5ddba
Autor:
Toby Mansell, Richard Saffery, Satvika Burugupalli, Anne-Louise Ponsonby, Mimi LK Tang, Martin O'Hely, Siroon Bekkering, Adam Alexander T Smith, Rebecca Rowland, Sarath Ranganathan, Peter D Sly, Peter Vuillermin, Fiona Collier, Peter Meikle, David Burgner, Barwon Infant Study Investigator Group
Publikováno v:
eLife, Vol 11 (2022)
Background: The risk of adult onset cardiovascular and metabolic (cardiometabolic) disease accrues from early life. Infection is ubiquitous in infancy and induces inflammation, a key cardiometabolic risk factor, but the relationship between infection
Externí odkaz:
https://doaj.org/article/3717633ff6504fb99ff75255c72b0e3a
Autor:
Satvika Burugupalli, Adam Alexander T Smith, Gavriel Oshlensky, Kevin Huynh, Corey Giles, Tingting Wang, Alexandra George, Sudip Paul, Anh Nguyen, Thy Duong, Natalie Mellett, Michelle Cinel, Sartaj Ahmad Mir, Li Chen, Markus R Wenk, Neerja Karnani, Fiona Collier, Richard Saffery, Peter Vuillermin, Anne-Louise Ponsonby, David Burgner, Peter Meikle, Barwon Infant Study Investigator team
Publikováno v:
eLife, Vol 11 (2022)
Background: There is mounting evidence that in utero and early life exposures may predispose an individual to metabolic disorders in later life; and dysregulation of lipid metabolism is critical in such outcomes. However, there is limited knowledge a
Externí odkaz:
https://doaj.org/article/fc3b0dc55b5e422ba351f4ecddae644f
Autor:
Gerard Pernes, Pooranee K Morgan, Kevin Huynh, Corey Giles, Sudip Paul, Adam Alexander T Smith, Natalie A Mellett, Camilla Bertuzzo Veiga, Thomas JC Collins, T Michael De Silva, Man KS Lee, Peter J Meikle, Graeme I Lancaster, Andrew J Murphy
The cellular lipidome is comprised of thousands of unique lipid species. This complexity underpins the many roles of lipids in cellular biology. How lipidome composition varies between cell types and how such differences contribute to cell-specific f
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::655ad93c6f4343317ce82a95c9c91bfb
https://doi.org/10.1101/2023.02.10.528075
https://doi.org/10.1101/2023.02.10.528075
Autor:
Adam Alexander T. Smith, Christopher C. Rowe, Andrew J. Saykin, Rebecca Baillie, Brian G. Drew, Matthias Arnold, Wei Ling Florence Lim, Xianlin Han, Gavriel Olshansky, Victor L. Villemagne, Corey Giles, Natalie A. Mellett, Ashley I. Bush, Rima Kaddurah-Daouk, Peter J. Meikle, Ralph N. Martins, Agus Salim, Simon M. Laws, Pratishtha Chatterjee, Kevin Huynh, Kaushala S. Jayawardana, David Ames, Ian Martins, Colin L. Masters, Kwangsik Nho
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-11 (2020)
Nat. Commun. 11:5698 (2020)
Nature Communications
Nat. Commun. 11:5698 (2020)
Nature Communications
Changes to lipid metabolism are tightly associated with the onset and pathology of Alzheimer’s disease (AD). Lipids are complex molecules comprising many isomeric and isobaric species, necessitating detailed analysis to enable interpretation of bio
Autor:
Diane Muller, Adam Alexander T. Smith, Bronwyn Sweeney, Mark Huthwaite, Philippa H. Gander, Sarah-Jane Paine, T. Leigh Signal, Monique Priston, Kathryn A. Lee
Publikováno v:
Sleep Health. 6:65-70
Objectives To investigate the association between measures of sleep quality, sleep duration and sleep disorder symptoms in late pregnancy and likelihood of emergency caesarean section. Design Population-based prospective cohort study Setting New Zeal