Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Adam Al-Kashi"'
Autor:
Adam Al-Kashi, Trinidad Montero-Melendez, Niloufar Moradi-Bidhendi, James P Gilligan, Nozer Mehta, Mauro Perretti
Publikováno v:
PLoS ONE, Vol 8, Iss 2, p e54299 (2013)
INTRODUCTION: Previous work reported the anti-arthritic synergy afforded by combining calcitonin (CT) and glucocorticoids (GC). Here we focus on the pairing of elcatonin (eCT) and dexamethasone (Dex), querying whether: i) this was a class-effect acti
Externí odkaz:
https://doaj.org/article/7c108bd838b84a84b1a1f147a07fcf00
Autor:
Niloufar Moradi-Bidhendi, James P. Gilligan, Trinidad Montero-Melendez, Adam Al-Kashi, Mauro Perretti, Nozer M. Mehta
Publikováno v:
PLoS ONE
PLoS ONE, Vol 8, Iss 2, p e54299 (2013)
PLoS ONE, Vol 8, Iss 2, p e54299 (2013)
Introduction Previous work reported the anti-arthritic synergy afforded by combining calcitonin (CT) and glucocorticoids (GC). Here we focus on the pairing of elcatonin (eCT) and dexamethasone (Dex), querying whether: i) this was a class-effect actio
Publikováno v:
Arthritis and rheumatism. 64(6)
Objective The induction of rheumatoid arthritis (RA) by active and passive immunization of mice results in the development of pain at the same time as the swelling and inflammation, with both peripheral and central sensitization contributing to joint
Publikováno v:
The FASEB Journal. 24
Rheumatoid arthritis (RA) is a common autoimmune disease (1% prevalence; 3:1 women to men ratio) characterised by chronic progressive joint destruction and pain, and accompanied by extra-articular manifestations, such as lung fibrosis. Glucocorticoid
Autor:
Francesco Dell'Accio, Adam Al-Kashi, Christina Subang, N.M. Eltawil, Chris Hughes, Michael Seed, Cosimo De Bari, Bjarne Faurholm, Alessandra Marrelli, Antonio Manzo, Ahuva Nissim, Yuti Chernajovsky, David Gould, Paul G. Winyard
Publikováno v:
Arthritis and Rheumatism
Objective To demonstrate that posttranslational modification of type II collagen (CII) by reactive oxygen species (ROS), which are known to be present in inflamed arthritic joints, can give rise to epitopes specific to damaged cartilage in rheumatoid
Autor:
Adam Al-Kashi, Peter J. Jose, Sarah J. Collington, Hugh R. P. Miller, Charlotte L. Weller, Adele Hartnell, Jeremy K. Brown, Timothy J. Williams, Peter Clark
Publikováno v:
The Journal of Experimental Medicine
Mast cells are tissue-resident cells with important functions in allergy and inflammation. Pluripotential hematopoietic stem cells in the bone marrow give rise to committed mast cell progenitors that transit via the blood to tissues throughout the bo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::26bc64d6eba7324a41fa3036d108e651
http://hdl.handle.net/10044/1/28130
http://hdl.handle.net/10044/1/28130
Autor:
Paul G. Winyard, Yuti Chernajovsky, Bjarne Faurholm, Francesco Dell'Accio, Chris Hughes, Michael Seed, Adam Al-Kashi, Antonio Manzo, Ahuva Nissim, Alessandra Amarrelli, N.M. Eltawil
Publikováno v:
Annals of the Rheumatic Diseases. 71:A7.2-A7
Background The aim of our study is to target anti-inflammatory proteins to arthritic joints, in order to improve efficacy and reduce side-effects of current therapies. Methods The authors chose type II collagen (CII) as a target as it is uniquely pre