Zobrazeno 1 - 10
of 49
pro vyhledávání: '"Adam A, Strömstedt"'
Publikováno v:
Toxins, Vol 16, Iss 5, p 209 (2024)
Peptide toxins from marine invertebrates have found use as drugs and in biotechnological applications. Many marine habitats, however, remain underexplored for natural products, and the Southern Ocean is among them. Here, we report toxins from one of
Externí odkaz:
https://doaj.org/article/bf76587f19b34c9a8726613f9163f6f3
Publikováno v:
Biomedicines, Vol 11, Iss 2, p 504 (2023)
Is it possible to enhance structural stability and biological activity of KR-12, a truncated antimicrobial peptide derived from the human host defense peptide LL-37? Based on the mapping of essential residues in KR-12, we have designed backbone-cycli
Externí odkaz:
https://doaj.org/article/322bafe0803149fb8063fe69cfdd9f39
Publikováno v:
Frontiers in Microbiology, Vol 11 (2020)
Can antimicrobial activity and peptide stability of alpha-helical peptides be increased by making them into dimers and macrocycles? Here, we explore that concept by using KR-12 as the starting point for peptide engineering. KR-12 has previously been
Externí odkaz:
https://doaj.org/article/5fae4e178ad24a84a12c16fcf1592179
Autor:
Sanjeevan Rajendran, Blazej Slazak, Supun Mohotti, Taj Muhammad, Adam A. Strömstedt, Małgorzata Kapusta, Emilia Wilmowicz, Ulf Göransson, Chamari M. Hettiarachchi, Sunithi Gunasekera
Cyclotides are an intriguing class of structurally stable circular miniproteins of plant origin with numerous potential pharmaceutical and agricultural applications. To investigate the occurrence of cyclotides in Sri Lankan flora, 50 medicinal plants
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::79fbf5749a828d1e6be6af96c869f655
http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-501761
http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-501761
Autor:
Blazej Slazak, Małgorzata Kapusta, Adam A. Strömstedt, Aneta Słomka, Marta Krychowiak, Mohammadreza Shariatgorji, Per E. Andrén, Jerzy Bohdanowicz, Elżbieta Kuta, Ulf Göransson
Publikováno v:
Frontiers in Plant Science, Vol 9 (2018)
Cyclotides are cyclic plant polypeptides of 27–37 amino acid residues. They have been extensively studied in bioengineering and drug development contexts. However, less is known about the relevance of cyclotides for the plants producing them. The a
Externí odkaz:
https://doaj.org/article/0dfe443f2018404e84c6a8fbbd982bd8
Autor:
Sanjeevan, Rajendran, Blazej, Slazak, Supun, Mohotti, Taj, Muhammad, Adam A, Strömstedt, Małgorzata, Kapusta, Emilia, Wilmowicz, Ulf, Göransson, Chamari M, Hettiarachchi, Sunithi, Gunasekera
Publikováno v:
Journal of natural products.
Cyclotides are an intriguing class of structurally stable circular miniproteins of plant origin with numerous potential pharmaceutical and agricultural applications. To investigate the occurrence of cyclotides in Sri Lankan flora, 50 medicinal plants
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::be213ee66633652741e5eb067b1b2ed2
https://pubmed.ncbi.nlm.nih.gov/36525646
https://pubmed.ncbi.nlm.nih.gov/36525646
Autor:
Judith Raschig, Daniela Mailänder-Sánchez, Anne Berscheid, Jürgen Berger, Adam A Strömstedt, Lioba F Courth, Nisar P Malek, Heike Brötz-Oesterhelt, Jan Wehkamp
Publikováno v:
PLoS Pathogens, Vol 13, Iss 3, p e1006261 (2017)
Ever since the discovery of endogenous host defense antimicrobial peptides it has been discussed how these evolutionary conserved molecules avoid to induce resistance and to remain effective. Human ß-defensin 1 (hBD1) is an ubiquitously expressed en
Externí odkaz:
https://doaj.org/article/eb4f9917cab541e084dbecbdd4562002
Autor:
John Kerr White, Taj Muhammad, Emelie Alsheim, Soumitra Mohanty, Anna Blasi-Romero, Sunithi Gunasekera, Adam A. Strömstedt, Natalia Ferraz, Ulf Göransson, Annelie Brauner
Publikováno v:
Cellular and Molecular Life Sciences. 79
The increasing antibiotic resistance among uropathogenic bacteria warrants alternative therapeutic strategies. We demonstrate the potential of the synthetic peptide CD4-PP, designed by dimerization and backbone cyclization of the shortest antimicrobi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e933870610f46b4e8a712b14d1f921c3
https://doi.org/10.1007/s00018-022-04440-w
https://doi.org/10.1007/s00018-022-04440-w
Autor:
Adam A. Strömstedt, Lina Nyström, Mariena J. A. van der Plas, Li Li, Martin Malmsten, Sara Malekkhaiat Häffner
Publikováno v:
Journal of Colloid and Interface Science. 562:71-80
Effects of size and charge of anionic nanoclays on their interactions with bacteria-mimicking lipid membranes, bacterial lipopolysaccharide (LPS), and Gram-negative bacteria were investigated using ellipsometry, dynamic light scattering, ζ-potential
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::720b88d1e63f16a08f6ba2e518098e7c
https://doi.org/10.1016/j.jcis.2019.11.110
https://doi.org/10.1016/j.jcis.2019.11.110
Publikováno v:
PLoS ONE, Vol 9, Iss 4, p e93685 (2014)
Aspergillus fumigatus is the most common causative agent of mold diseases in humans, giving rise to life-threatening infections in immunocompromised individuals. One of its secreted metabolites is gliotoxin, a toxic antimicrobial agent. The aim of th
Externí odkaz:
https://doaj.org/article/9d1bbcc5e6634814b65ad283f9690221