Zobrazeno 1 - 10
of 47
pro vyhledávání: '"Adam Rainczuk"'
Publikováno v:
Frontiers in Chemistry, Vol 9 (2021)
Native mass spectrometry has emerged as a powerful tool for structural biology as it enables the evaluation of molecules as they occur in their physiological conditions. Ion mobility spectrometry-mass spectrometry (IMS-MS) has shown essential in thes
Externí odkaz:
https://doaj.org/article/67998da1ada14ecc8b2ead276a058971
Autor:
Sung-Woog Kang, Adam Rainczuk, Martin K. Oehler, Thomas W. Jobling, Magdalena Plebanski, Andrew N. Stephens
Publikováno v:
Diagnostics, Vol 11, Iss 6, p 1048 (2021)
Background: Despite substantial effort, there remains a lack of biomarker-based, clinically relevant testing for the accurate, non-invasive diagnostic or prognostic profiling of epithelial ovarian cancers (EOC). Our previous work demonstrated that wh
Externí odkaz:
https://doaj.org/article/23b809b8fffc472c8fb71a1244e5d58f
Autor:
Trang Nguyen, Dilys T.H. Leung, John Silke, Peter J. Fuller, Simon Chu, Adam Rainczuk, Andrew N. Stephens
Publikováno v:
Journal of Proteome Research. 18:1691-1702
Ovarian granulosa cell tumors (GCTs) are hormonally active cancers characterized by indolent growth and late, invasive relapse. No therapies have yet proven to be efficacious. We previously reported that the inhibition of the antiapoptotic X-linked i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::df8b0af56e9710c3e2fa393b626fc5bb
https://doi.org/10.1021/acs.jproteome.8b00917
https://doi.org/10.1021/acs.jproteome.8b00917
Autor:
Ellen Melaleuca Menkhorst, Natalie Lane, Amy Louise Winship, Priscilla Li, Joanne Yap, Katie Meehan, Adam Rainczuk, Andrew Stephens, Evdokia Dimitriadis
Publikováno v:
PLoS ONE, Vol 7, Iss 2, p e31418 (2012)
Inadequate or inappropriate implantation and placentation during the establishment of human pregnancy is thought to lead to first trimester miscarriage, placental insufficiency and other obstetric complications. To create the placental blood supply,
Externí odkaz:
https://doaj.org/article/179ba12a94fe4198a68d26a14522b2fb
Autor:
Laura R. Moffitt, Adam Rainczuk, Magdalena Plebanski, Andrew N. Stephens, Tom Jobling, Amy L. Wilson, Nadine Duffield
Publikováno v:
Cancer Epidemiology, Biomarkers & Prevention. 27:183-192
Background: Tumor-directed circulating autoantibodies (AAb) are a well-established feature of many solid tumor types, and are often observed prior to clinical disease manifestation. As such, they may provide a good indicator of early disease developm
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7c31ac0cff178f1b5be25f076f8401d1
https://doi.org/10.1158/1055-9965.epi-17-0752
https://doi.org/10.1158/1055-9965.epi-17-0752
Autor:
Andrew N. Stephens, Sung-Woog Kang, Tom Jobling, Martin K. Oehler, Adam Rainczuk, Magdalena Plebanski
Publikováno v:
Diagnostics, Vol 11, Iss 1048, p 1048 (2021)
Diagnostics
Volume 11
Issue 6
Diagnostics
Volume 11
Issue 6
Background: Despite substantial effort, there remains a lack of biomarker-based, clinically relevant testing for the accurate, non-invasive diagnostic or prognostic profiling of epithelial ovarian cancers (EOC). Our previous work demonstrated that wh
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7fe9eaec789b16e1e4a02248cbbc64f9
https://doi.org/10.3390/diagnostics11061048
https://doi.org/10.3390/diagnostics11061048
Autor:
Andrew N. Stephens, Adam Rainczuk, Emma Green, Tom Jobling, Nicole Fairweather, Maree Bilandzic, Magdalena Plebanski
Publikováno v:
Cancers
Volume 11
Issue 9
Cancers, Vol 11, Iss 9, p 1228 (2019)
Volume 11
Issue 9
Cancers, Vol 11, Iss 9, p 1228 (2019)
Epithelial ovarian cancer metastasis is driven by spheroids, which are heterogeneous cancer cell aggregates released from the primary tumour mass that passively disseminate throughout the peritoneal cavity to promote tumour spread, disease recurrence
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4dd9f1a0ba8f6766d97690e6d1167e37
Autor:
Maree Bilandzic, Amy L. Wilson, Kirsty Wilson, Martin K. Oehler, Adam Rainczuk, Andrew N. Stephens, Laura R. Moffitt, Ming Makanji, Magdalena Plebanski, Mark D. Gorrell
Publikováno v:
Cancers
Volume 11
Issue 1
Cancers, Vol 11, Iss 1, p 32 (2018)
Volume 11
Issue 1
Cancers, Vol 11, Iss 1, p 32 (2018)
Ovarian cancers (OCs) are the most lethal gynaecological malignancy, with high levels of relapse and acquired chemo-resistance. Whilst the tumour&ndash
immune nexus controls both cancer progression and regression, the lack of an appropriate syst
immune nexus controls both cancer progression and regression, the lack of an appropriate syst
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c238c0f5ce357a545bc855e9876ec1a8
Autor:
Josie Lawrence, Sadiqa Maqsudi, Andrew N. Stephens, Adam Rainczuk, Fiona M. Keane, Mark D. Gorrell, Hui Zhang, Daniela Justa-Schuch, Ruth Geiss-Friedlander, Nadine Duffield
Publikováno v:
FEBS Journal. 282:3737-3757
Dipeptidyl peptidase 9 (DPP9) is a member of the S9B/DPPIV (DPP4) serine protease family, which cleaves N-terminal dipeptides at an Xaa-Pro consensus motif. Cytoplasmic DPP9 has roles in epidermal growth factor signalling and in antigen processing, w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5b1df19e02da27bd9103630e87dd0181
https://doi.org/10.1111/febs.13371
https://doi.org/10.1111/febs.13371
Autor:
Ming Makanji, Peter G. Stanton, Daniel J. Garama, Adam Rainczuk, Jarrod J. Sandow, Tom Jobling, Nicole Fairweather, Andrew N. Stephens, Amy L. Wilson, Maree Bilandzic, Andrew I. Webb, Giuseppe Infusini, Daniel J. Gough
Publikováno v:
Proteomics. Clinical applications. 12(3)
Purpose For the vast majority of ovarian cancer patients, optimal surgical debulking remains a key prognostic factor associated with improved survival. A standardized, biomarker-based test, to preoperatively discriminate benign from malignant disease
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cd1b57bef7af2798a7ca4ee79ccd29f9
https://pubmed.ncbi.nlm.nih.gov/29426060
https://pubmed.ncbi.nlm.nih.gov/29426060