Zobrazeno 1 - 10
of 104
pro vyhledávání: '"Adam, Kuspa"'
Publikováno v:
Nature Communications, Vol 7, Iss 1, Pp 1-9 (2016)
Neutrophils secrete net-like structures made of DNA and anti-microbial peptides, which can trap and kill extracellular pathogens. Here, the authors show that such nets are also produced by so-called Sentinel cells in the multicellular slug stage of t
Externí odkaz:
https://doaj.org/article/8990ab6b27c443b2938ef55fcaa4a346
Autor:
Michelle Rubin, Amber D Miller, Mariko Katoh-Kurasawa, Christopher Dinh, Adam Kuspa, Gad Shaulsky
Publikováno v:
PLoS ONE, Vol 14, Iss 1, p e0209438 (2019)
The eukaryotic amoeba Dictyostelium discoideum is commonly used to study sociality. The amoebae cooperate during development, exhibiting altruism, cheating, and kin-discrimination, but growth while preying on bacteria has been considered asocial. Her
Externí odkaz:
https://doaj.org/article/d672ea2856f54dff9b6a6f7c51134909
Publikováno v:
PLoS Computational Biology, Vol 11, Iss 10, p e1004552 (2015)
Data integration procedures combine heterogeneous data sets into predictive models, but they are limited to data explicitly related to the target object type, such as genes. Collage is a new data fusion approach to gene prioritization. It considers d
Externí odkaz:
https://doaj.org/article/3db88e6e2baf476282ff43473e8cb746
Autor:
Edward Roshan Miranda, Olga Zhuchenko, Marko Toplak, Balaji Santhanam, Blaz Zupan, Adam Kuspa, Gad Shaulsky
Publikováno v:
PLoS ONE, Vol 8, Iss 8, p e70040 (2013)
ATP-binding cassette (ABC) transporters can translocate a broad spectrum of molecules across the cell membrane including physiological cargo and toxins. ABC transporters are known for the role they play in resistance towards anticancer agents in chem
Externí odkaz:
https://doaj.org/article/7dc053817cd04676828730a41750a0fd
Autor:
Joan E. Strassmann, Richard Sucgang, Takaaki B. Narita, Richard A. Gibbs, Adam Kuspa, Stephen Richards, Kim C. Worley, Koryu Kin, Donna M. Muzny, Pauline Schaap, Yoshinori Kawabe
Publikováno v:
Genome Biology and Evolution
Major phenotypic innovations in social amoeba evolution occurred at the transition between the Polysphondylia and group 4 Dictyostelia, which comprise the model organism Dictyostelium discoideum, such as the formation of a new structure, the basal di
Animal defenses directed against bacteria include DNA-based extracellular traps (ETs) that are produced by innate immune cells. ET-bound bacteria are prevented from further tissue dissemination and are eventually killed by ET-bound antibacterial prot
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f9968acb34e1c3bde788360d24f6277b
https://doi.org/10.1101/2020.05.04.077404
https://doi.org/10.1101/2020.05.04.077404
Autor:
Gad Shaulsky, Adam Kuspa
Publikováno v:
The International Journal of Developmental Biology. 63:343-357
William Farnsworth Loomis studied the social amoeba Dictyostelium discoideum for more than fifty years as a professor of biology at the University of California, San Diego, USA. This biographical reflection describes Dr. Loomis’ major scientific co
Autor:
Chenyu Zhang, Adam Kuspa
Publikováno v:
PLoS ONE, Vol 4, Iss 5, p e5706 (2009)
Bacterial pathogens employ a variety of survival strategies when they invade eukaryotic cells. The amoeba Dictyostelium discoideum is used as a model host to study the pathogenic mechanisms that Legionella pneumophila, the causative agent of Legionna
Externí odkaz:
https://doaj.org/article/47056a90aa664bd684a136c82b6b844e
Publikováno v:
PLoS Computational Biology, Vol 1, Iss 7, p e71 (2005)
The Amoebozoa are a sister clade to the fungi and the animals, but are poorly sampled for completely sequenced genomes. The social amoeba Dictyostelium discoideum and amitochondriate pathogen Entamoeba histolytica are the first Amoebozoa with genomes
Externí odkaz:
https://doaj.org/article/0eee88d7e481442081f6da4f5209273b
Autor:
Christopher Dinh, Michelle Rubin, Mariko Katoh-Kurasawa, Amber D. Miller, Gad Shaulsky, Adam Kuspa
Publikováno v:
PLoS ONE, Vol 14, Iss 1, p e0209438 (2019)
PLoS ONE
PLoS ONE
The eukaryotic amoeba Dictyostelium discoideum is commonly used to study sociality. The amoebae cooperate during development, exhibiting altruism, cheating, and kin-discrimination, but growth while preying on bacteria has been considered asocial. Her