Compassionate Use of Remdesivir in Pregnant Women With Severe Coronavirus Disease 2019

Autor: Samit Desai, Kristen M. Marks, Suzanne J Rose, Sigal Yawetz, Pritha Sen, Shawn Mazur, Jose F. Suarez, Diana M. Brainard, Yang Zhao, Matthew D Sims, Moupali Das, Magdalena E. Sobieszczyk, Cecilia Big, Ilona T. Goldfarb, Brian G. Blackburn, Ai-ris Y. Collier, Christoph C Carter, Susanna K Tan, Olga A. Kovalenko, Geeta K. Swamy, William R. Short, Jason Hindman, Adam DeZure, Tom Hahambis, Richard M. Burwick, Gregory Morlin, Adi Hirshberg, Anu Osinusi, Rebecca Zash, Laura Telep, Tilly A. Varughese, Anand P Chokkalingam, Mariam Naqvi, E Milunka Kojic, Kathryn E. Stephenson, Jeanne S. Sheffield, Oriol Manuel

Publikováno v: Clinical Infectious Diseases: An Official Publication of the Infectious Diseases Society of America
Clinical Infectious Diseases
Clinical infectious diseases, vol. 73, no. 11, pp. e3996-e4004

Background Remdesivir is efficacious for severe coronavirus disease 2019 (COVID-19) in adults, but data in pregnant women are limited. We describe outcomes in the first 86 pregnant women with severe COVID-19 who were treated with remdesivir. Methods

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::960db2fc8d8b75b03d065f1e9f19bb23
https://doi.org/10.1093/cid/ciaa1466

Compassionate Use of Remdesivir for Patients with Severe Covid-19

Autor: Jennifer Cunningham, Marta Mora-Rillo, Robert P. Myers, Gary M. Green, Polly Desai, Toshitaka Maeno, Antonella D’Arminio Monforte, Yoshikazu Mutoh, Emanuele Nicastri, Ilana Henne, Susanna K. Tan, Erika Asperges, Jonathan Grein, Saad Ismail, Alex Studemeister, Rentaro Oda, Anuj Gaggar, Anu Osinusi, Kikuo Yo, Erwan L’Her, Huyen Cao, Hideaki Kato, Duc Nguyen, Seema Ahmed, Daniel Shin, Marco Massari, John Redinski, Giuseppe Lapadula, Lijie Zhong, Shingo Chihara, Laura Telep, Alexander Zoufaly, Daniel Chelliah, Ewa Verweij, Timothy Flanigan, Lucinda Winterbourne, Robertino Mera, Eugenia Quiros-Roldan, Diana M. Brainard, Adam DeZure, Leighann Timbs, Norio Ohmagari, Stuart H. Cohen, Sumit Majumder, Richard Childs, François-Xavier Lescure, Jorge Bernett, Emon Elboudwarej, Yang Zhao, Anand Chokkalingam, Scott Sellers, George Diaz, Torsten Feldt, Margaret L. Green, Danny Chen, Antonella Castagna

Publikováno v: New England Journal of Medicine
The New England Journal of Medicine
The New England journal of medicine, vol 382, iss 24

Background Remdesivir, a nucleotide analogue prodrug that inhibits viral RNA polymerases, has shown in vitro activity against SARS-CoV-2. Methods We provided remdesivir on a compassionate-use basis to patients hospitalized with Covid-19, the illness

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::688960eeb6323fd77d983d336dbcced5
https://pubmed.ncbi.nlm.nih.gov/33128490

Somatic STAT5b gain-of-function mutations in early onset nonclonal eosinophilia, urticaria, dermatitis, and diarrhea

Autor: Michelle Makiya, Sergio D. Rosenzweig, Maureen J. O'Sullivan, Chi Ma, Adam DeZure, Jennifer Stoddard, Joshua D. Milner, Alexandra F. Freeman, Julie E. Niemela, Amy D. Klion, Stefania Pittaluga, Sophie Hambleton, Brian Cauff, Mark Raffeld, Grainne M. O'Regan, Liqiang Xi, T. Ronan Leahy, Gary Kleiner

Publikováno v: Blood. 129:650-653

To the editor: Somatic, gain-of-function mutations in STAT3 and STAT5 have been described in leukemias and lymphomas[1][1][⇓][2][⇓][3][⇓][4][⇓][5]-[6][6] and, more recently, in CD3-CD4+ T cells from a patient with lymphocytic variant hypereos

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4f62ef78bd6adb55e37f4cfb2dfb078f
https://doi.org/10.1182/blood-2016-09-737817

Corrigendum: Protection against malaria at 1 year and immune correlates following PfSPZ vaccination

Autor: Andrew S, Ishizuka, Kirsten E, Lyke, Adam, DeZure, Andrea A, Berry, Thomas L, Richie, Floreliz H, Mendoza, Mary E, Enama, Ingelise J, Gordon, Lee-Jah, Chang, Uzma N, Sarwar, Kathryn L, Zephir, LaSonji A, Holman, Eric R, James, Peter F, Billingsley, Anusha, Gunasekera, Sumana, Chakravarty, Anita, Manoj, MingLin, Li, Adam J, Ruben, Tao, Li, Abraham G, Eappen, Richard E, Stafford, Natasha, K C, Tooba, Murshedkar, Hope, DeCederfelt, Sarah H, Plummer, Cynthia S, Hendel, Laura, Novik, Pamela J M, Costner, Jamie G, Saunders, Matthew B, Laurens, Christopher V, Plowe, Barbara, Flynn, William R, Whalen, J P, Todd, Jay, Noor, Srinivas, Rao, Kailan, Sierra-Davidson, Geoffrey M, Lynn, Judith E, Epstein, Margaret A, Kemp, Gary A, Fahle, Sebastian A, Mikolajczak, Matthew, Fishbaugher, Brandon K, Sack, Stefan H I, Kappe, Silas A, Davidson, Lindsey S, Garver, Niklas K, Björkström, Martha C, Nason, Barney S, Graham, Mario, Roederer, B Kim Lee, Sim, Stephen L, Hoffman, Julie E, Ledgerwood, Robert A, Seder

Publikováno v: Nature medicine. 22(6)

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::5ad1dfd70edeebc696235ee5718145d9
https://pubmed.ncbi.nlm.nih.gov/27158907

Vaccines for Emerging Viral Diseases

Autor: Adam DeZure, Barney S. Graham

Infectious diseases continue to plague mankind and evolve to keep pace with the efforts to control them. Sir William Osler captured the ongoing fear of infectious pathogens when he said, “Humanity has but three great enemies: fever, famine, and war

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::142c0a1d960fa36faadab324cb97b33f
https://doi.org/10.1016/b978-0-12-802174-3.00028-x