Zobrazeno 1 - 10
of 28
pro vyhledávání: '"Adalberto R. Santos"'
Autor:
Viviane da C. Silva, Raquel L. de F. Teixeira, Rebecca E. E. N. O. do Livramento, Márcia Q. P. Lopes, Thyago Leal-Calvo, José E. Filho, Márcia B. V. Luduvice, Lilian de C. Rodrigues, Marcello Bossois, Patricia F. Schlinkert, Anderson S. Neves, Philip N. Suffys, José Roberto Lapa e Silva, Adalberto R. Santos
Publikováno v:
Current Issues in Molecular Biology, Vol 46, Iss 7, Pp 6951-6959 (2024)
Asthma is a chronic inflammatory respiratory condition, characterized by variable airflow limitation, leading to clinical symptoms such as dyspnea and chest tightness. These symptoms result from an underlying inflammatory process. The β2 agonists ar
Externí odkaz:
https://doaj.org/article/34bcbcf618924ea193a4730ecce4c1f7
Autor:
Patrícia Duarte Deps, Adalberto R. Santos, João Marcelo Azevedo de Paula Antunes, Simon M Collin
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 14, Iss 3, p e0008127 (2020)
Deps, P, Antunes, J M, Santos, A R & Collin, S M 2020, ' Prevalence of Mycobacterium leprae in armadillos in Brazil : A systematic review and meta-analysis ', PLoS Neglected Tropical Diseases, vol. 14, no. 3, e0008127 . https://doi.org/10.1371/journal.pntd.0008127
PLoS Neglected Tropical Diseases
Deps, P, Antunes, J M, Santos, A R & Collin, S M 2020, ' Prevalence of Mycobacterium leprae in armadillos in Brazil : A systematic review and meta-analysis ', PLoS Neglected Tropical Diseases, vol. 14, no. 3, e0008127 . https://doi.org/10.1371/journal.pntd.0008127
PLoS Neglected Tropical Diseases
Understanding the prevalence of M. leprae infection in armadillos is important because of evidence from Brazil and other countries of an association between contact with armadillos and the development of Hansen’s Disease (leprosy). Our aim was to c
Autor:
Elis Regina Dalla Costa, Maria Lucia Rosa Rossetti, Márcia Susana Nunes Silva, Sidra Ezidio Gonçalves Vasconcellos, Ricardo Martins Ramos, Millene Borges Coelho, Natali Linck, Adalberto R. Santos, Pedro Eduardo Almeida da Silva, Hermes Luís Neubauer de Amorim, Daniela Fernandes Ramos, Philip Noel Suffys
Publikováno v:
Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis. 712:33-39
The present study was carried out to investigate the presence of polymorphism in the N-acetyltransferase gene of 41 clinical isolates of Mycobacterium tuberculosis, that were resistant to isoniazid (INH) with no mutations in the hot spots of the gene
Autor:
Tatiana Schäffer Gregianini, Arnaldo Zaha, Patrícia Izquierdo Cafrune, Lia Gonçalves Possuelo, T. C. de Brito, Mara H. Hutz, J. A. Castelan, Raquel Lima de Figueiredo Teixeira, Maria Lucia Rosa Rossetti, Adalberto R. Santos, Andrezza Wolowski Ribeiro, P. D. Picon
Publikováno v:
European Journal of Clinical Pharmacology. 64:673-681
To determine the frequency of N-acetyltransferase 2 (NAT2) polymorphisms, the NAT2 acetylation profile and its relation to the incidence of gastrointestinal adverse drug reactions (ADRs), anti-tuberculosis (TB) drug-induced hepatotoxicity, and the cl
Autor:
Joseane Fonseca-Costa, Adalberto R. Santos, Fernanda Carvalho de Queiroz Mello, Marcelo Fouad Rabahi, Antonio Basílio de Miranda, Antonio G. Pacheco, Raquel Lima de Figueiredo Teixeira, Afrânio Lineu Kritski, Philip Noel Suffys, Hedi Marinho de Melo, Márcia Quinhones Pires Lopes
Publikováno v:
Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis. 624:31-40
Arylamine N-acetyltranferase 2 is the main enzyme responsible for the isoniazid metabolization into hepatotoxic intermediates and the degree of hepatotoxicity severity has been attributed to genetic variability in the NAT2 gene. The main goal of this
Autor:
Joseane F. Costa, Lúcia Helena Amim, Martha Maria Oliveira, Carla Loredo, Hedi Marinho de Melo, Fernanda Carvalho de Queiroz Mello, Afrânio Lineu Kritski, Luiz F. Queiroz, José Roberto Lapa e Silva, Jocilea C. S. da Silva, Adalberto R. Santos
Publikováno v:
Jornal Brasileiro de Pneumologia. 30:371-377
INTRODUÇÃO: Fatores genéticos podem desempenhar um importante papel na susceptibilidade à tuberculose (TB) ativa, e polimorfismos de base única (SNPs) em diferentes genes que codificam para citocinas têm sido descritos e associados com doenças
Autor:
Osvaldo J. M. Nascimento, Leila Chimelli, Anna Maria Sales, Ximena Illarramendi, Sérgio Luiz Gomes Antunes, Elizabeth P. Sampaio, Euzenir Nunes Sarno, Adalberto R. Santos, Márcia Rodrigues Jardim, José Augusto da Costa Nery, Nádia Cristina Duppre
Publikováno v:
Journal of Neurology. 250:806-809
The clinical diagnosis of pure neural leprosy (PNL) remains a public health care problem mainly because skin lesions-the cardinal features of leprosy-are always absent.Moreover, the identification of the leprosy bacillus is not easily achieved even w
Autor:
Pedro Hernan Cabello, Tom W J Huizinga, Tom H. M. Ottenhoff, Elizabeth P. Sampaio, Philip Noel Suffys, A Bakker, Euzenir Nunes Sarno, Adalberto R. Santos, Milton Ozório Moraes, Patricia R. Vanderborght, Haroldo José de Matos, Leila Maria Machado Vieira
Publikováno v:
The Journal of Infectious Diseases. 186:1687-1691
Single-nucleotide polymorphismswithin thegenescodingfortumornecrosisfactor(TNF)‐a and interleukin (IL)‐10 have been associated with several infectious diseases. To determine whether such polymorphisms are associated with leprosy, genotyping was p
Autor:
Lizânia Borges Spinassé, Gil F. Salles, Elizabeth S. Muxfeldt, Philip Noel Suffys, Adalberto R. Santos
Publikováno v:
Pharmacogenomics. 15(2)
Aim: Hydralazine, a vasodilator used in resistant hypertension (RH) treatment is metabolized by an acetylation reaction mediated by N-acetyltransferase 2, the activity of which depends on NAT2 polymorphisms. Our aim was to evaluate whether different
Autor:
Flávio Tannure, Lia Lima Gomes, Michel K. Gomgnimbou, Neio Boechat, Karla Valéria Batista Lima, Maria de Lourdes Leite, Emilyn Costa Conceição, Harrison Magdinier Gomes, Nalin Rastogi, Chyntia Carolina Diaz Acosta, Paulo Cesar de Souza Caldas, David Couvin, Philip Noel Suffys, Adalberto R. Santos, Marcelo Emanuel Ivens de Araujo, Christophe Sola, Sidra Ezidio Gonçalves Vasconcellos
Publikováno v:
PLoS ONE
PLoS ONE, Public Library of Science, 2014, 9 (10), pp.e107747. ⟨10.1371/journal.pone.0107747⟩
PLoS ONE, Vol 9, Iss 10, p e107747 (2014)
PLoS ONE, Public Library of Science, 2014, 9 (10), pp.e107747. ⟨10.1371/journal.pone.0107747⟩
PLoS ONE, Vol 9, Iss 10, p e107747 (2014)
International audience; Rio de Janeiro is endemic for tuberculosis (TB) and presents the second largest prevalence of the disease in Brazil. Here, we present the bacterial population structure of 218 isolates of Mycobacterium tuberculosis, derived fr