Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Ada X. Yee"'
Autor:
Tianbo Li, Martin Ginkel, Ada X. Yee, Leigh Foster, Jun Chen, Stephan Heyse, Stephan Steigele
Publikováno v:
SLAS Discovery, Vol 27, Iss 4, Pp 278-285 (2022)
Ion channels are drug targets for neurologic, cardiac, and immunologic diseases. Many disease-associated mutations and drugs modulate voltage-gated ion channel activation and inactivation, suggesting that characterizing state-dependent effects of tes
Externí odkaz:
https://doaj.org/article/0c6cb9340f7b43a0abde5b4e5da47769
Autor:
Morgan Sheng, Karpagam Srinivasan, Jesse E. Hanson, Josh Kaminker, Yuanyuan Wang, Melanie A. Huntley, David V. Hansen, Tzu-Ming Wang, Brad A. Friedman, Ada X. Yee
Publikováno v:
J Neurosci
Cortical circuit activity is shaped by the parvalbumin (PV) and somatostatin (SST) interneurons that inhibit principal excitatory (EXC) neurons and the vasoactive intestinal peptide (VIP) interneurons that suppress activation of other interneurons. T
Publikováno v:
Philosophical transactions of the Royal Society of London. Series B, Biological sciences. 372(1715)
Hebbian and homeostatic plasticity are two major forms of plasticity in the nervous system: Hebbian plasticity provides a synaptic basis for associative learning, whereas homeostatic plasticity serves to stabilize network activity. While achieving se
Autor:
Lu Chen, Ada X. Yee
Publikováno v:
Synapse (New York, N.Y.). 70(11)
Retinoic acid (RA), a developmental morphogen, has emerged in recent studies as a novel synaptic signaling molecule that acts in mature hippocampal neurons to modulate excitatory and inhibitory synaptic transmission in the context of homeostatic syna
Autor:
Alice C. Fan, Debabrita Deb-Basu, Jason Gotlib, Shelly Beer, Daryl Taketa, Roger A. O'Neill, Dean W. Felsher, Ada X Yee, Yasodha Natkunam, Amy E. Shirer, David Voehringer, Rose Ann Padua, Liwen Xu, Mathias W. Orban
Publikováno v:
Nature medicine. 15(5)
Current methods of protein detection are insensitive to detecting subtle changes in oncoprotein activation that underlie key cancer signaling processes. The requirement for large numbers of cells precludes serial tumor sampling for assessing a respon