Zobrazeno 1 - 10
of 22
pro vyhledávání: '"Ada W C Yan"'
Autor:
Arminder K Deol, Danny Scarponi, Peter Beckwith, Tom A Yates, Aaron S Karat, Ada W C Yan, Kathy S Baisley, Alison D Grant, Richard G White, Nicky McCreesh
Publikováno v:
PLoS ONE, Vol 16, Iss 6, p e0253096 (2021)
BackgroundIn light of the role that airborne transmission plays in the spread of SARS-CoV-2, as well as the ongoing high global mortality from well-known airborne diseases such as tuberculosis and measles, there is an urgent need for practical ways o
Externí odkaz:
https://doaj.org/article/a0eb36426cc44649a33d4a4325ee658f
Publikováno v:
PLoS Computational Biology, Vol 15, Iss 1, p e1006568 (2019)
Laboratory models are often used to understand the interaction of related pathogens via host immunity. For example, recent experiments where ferrets were exposed to two influenza strains within a short period of time have shown how the effects of cro
Externí odkaz:
https://doaj.org/article/641f7f5f73a04bd59c242e1867d36e2d
Autor:
Pengxing Cao, Ada W C Yan, Jane M Heffernan, Stephen Petrie, Robert G Moss, Louise A Carolan, Teagan A Guarnaccia, Anne Kelso, Ian G Barr, Jodie McVernon, Karen L Laurie, James M McCaw
Publikováno v:
PLoS Computational Biology, Vol 11, Iss 8, p e1004334 (2015)
Influenza is an infectious disease that primarily attacks the respiratory system. Innate immunity provides both a very early defense to influenza virus invasion and an effective control of viral growth. Previous modelling studies of virus-innate immu
Externí odkaz:
https://doaj.org/article/47c3cdb8e5d54088896c92a644d24881
Autor:
Clare P. McCormack, Ada W. C. Yan, Jonathan C. Brown, Ksenia Sukhova, Thomas P. Peacock, Wendy S. Barclay, Ilaria Dorigatti
We use viral kinetic models fitted to viral load data fromin vitrostudies to explain why the SARS-CoV-2 Omicron variant replicates faster than the Delta variant in nasal cells, but slower than Delta in lung cells, which could explain Omicron’s high
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bbafec52b43cd343e1534081600230d2
https://doi.org/10.1101/2023.03.15.529513
https://doi.org/10.1101/2023.03.15.529513
Autor:
Felicity Liew, Mahdi Moradi Marjaneh, Cher Y Foo, Joseph D. Challenger, Yue Wu, Lucy C Okell, Aubrey J. Cunnington, Ada W. C. Yan, Ryan S Thwaites
Publikováno v:
BMC Medicine, Vol 20, Iss 1, Pp 1-20 (2022)
BMC Medicine
BMC Medicine
Relationships between viral load, severity of illness, and transmissibility of virus are fundamental to understanding pathogenesis and devising better therapeutic and prevention strategies for COVID-19. Here we present within-host modelling of viral
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1e4dfb5fa88fe537da03b0be877d8fe3
https://doaj.org/article/36cf8f0e0cc8483b94a97df0da67611f
https://doaj.org/article/36cf8f0e0cc8483b94a97df0da67611f
Autor:
Wendy S. Barclay, Colin A. Russell, Ada W. C. Yan, Jie Zhou, Catherine A. A. Beauchemin, Steven Riley
Publikováno v:
Epidemics, Vol 33, Iss, Pp 100406-(2020)
Epidemics, 33:100406. Elsevier
Epidemics, 33:100406. Elsevier
When analysing in vitro data, growth kinetics of influenza virus strains are often compared by computing their growth rates, which are sometimes used as proxies for fitness. However, analogous to mathematical models for epidemics, the growth rate can
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0d004a9b9bb77eccb02f4d2a4494545f
http://hdl.handle.net/10044/1/83950
http://hdl.handle.net/10044/1/83950
Autor:
Jie Zhou, Monica Galiano, Daniel H. Goldhill, Shahjahan Miah, Wendy S. Barclay, Maria Zambon, Omolola Akinbami, Rebecca Frise, Jennifer Shelley, Ana Gallego Cortés, Angie Lackenby, Ada W. C. Yan
Publikováno v:
PLoS Pathogens
PLoS Pathogens, Vol 17, Iss 6, p e1008937 (2021)
PLoS Pathogens, Vol 17, Iss 6, p e1008937 (2021)
Favipiravir is a nucleoside analogue which has been licensed to treat influenza in the event of a new pandemic. We previously described a favipiravir resistant influenza A virus generated by in vitro passage in presence of drug with two mutations: K2
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0681a08f000b612a8e7b210bd5f48467
https://doi.org/10.1101/2020.09.01.277343
https://doi.org/10.1101/2020.09.01.277343
Autor:
Jonathan M. Keith, Jason M. Whyte, James N. Walker, Robert Moss, Freya M Shearer, Jennifer A. Flegg, Deborah Cromer, Alexander E. Zarebski, Lisa J. White, Ada W. C. Yan, Sarah Belet, Amani Abdullah Alahmadi, Pavithra Jayasundara, James M. McCaw, Joshua V. Ross, Thomas House, Andrew J. Black, Sai Thein Than Tun
Publikováno v:
Epidemics, Vol 32, Iss, Pp 100393-(2020)
Modern data and computational resources, coupled with algorithmic and theoretical advances to exploit these, allow disease dynamic models to be parameterised with increasing detail and accuracy. While this enhances models' usefulness in prediction an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3d08bd118cef9769c6ad9c81d9ca17ac
http://hdl.handle.net/10044/1/82507
http://hdl.handle.net/10044/1/82507
Autor:
Erik D. Surface, Taylor Chin, Kamran Khan, James A. Hay, Michael J. Mina, Caroline O. Buckee, Alexander Watts, Tigist F. Menkir, Ada W. C. Yan, Ryan Sherbo, Pablo Martinez de Salazar, Marc Lipsitch, Rene Niehus
Publikováno v:
medRxiv
article-version (status) pre
article-version (number) 2
Nature Communications
Nature Communications, Vol 12, Iss 1, Pp 1-10 (2021)
article-version (status) pre
article-version (number) 2
Nature Communications
Nature Communications, Vol 12, Iss 1, Pp 1-10 (2021)
Early in the COVID-19 pandemic, predictions of international outbreaks were largely based on imported cases from Wuhan, China, potentially missing imports from other cities. We provide a method, combining daily COVID-19 prevalence and flight passenge
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::94939d516905afa72d9e33d2fd5b9d83
https://doi.org/10.1101/2020.03.23.20038331
https://doi.org/10.1101/2020.03.23.20038331
Autor:
Vijaykrishna Dhanasekaran, Xiaoyun Yang, Tonghua Zhang, Stephen J. Turner, Shilian Xu, Leah Gillespie, Ada W. C. Yan, Moshe Olshansky, Heidi Peck, Ian G. Barr, Celeste M. Donato
Influenza virus is a major human health threat. Neutralizing antibodies elicited through prior infection or vaccination play an irreplaceable role in protection from subsequent infection. The efficacy of antibody-dependent vaccines relies on both vir
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fe3c2846fce4ef758a37bdc66f3a0b3f