Zobrazeno 1 - 10
of 22
pro vyhledávání: '"Ada Delaney"'
Publikováno v:
PLoS ONE, Vol 5, Iss 9, p e12498 (2010)
BACKGROUND:Response to painful stimuli is susceptible to genetic variation. Numerous loci have been identified which contribute to this variation, one of which, MC1R, is better known as a gene involved in mammalian hair colour. MC1R is a G protein-co
Externí odkaz:
https://doaj.org/article/b22de4fb5d1c412c9db537b8936ddfa7
Autor:
Jie Su, Emerson Krock, Swapnali Barde, Ada Delaney, Johnny Ribeiro, Jungo Kato, Nilesh Agalave, Gustaf Wigerblad, Rosalia Matteo, Roger Sabbadini, Anna Josephson, Jerold Chun, Kim Kultima, Olivier Peyruchaud, Tomas Hökfelt, Camilla I. Svensson
Publikováno v:
Brain, Behavior, and Immunity
Brain, Behavior, and Immunity, 2022, 101, pp.214-230. ⟨10.1016/j.bbi.2022.01.003⟩
Brain, Behavior, and Immunity, 2022, 101, pp.214-230. ⟨10.1016/j.bbi.2022.01.003⟩
International audience; Inflammatory and neuropathic-like components underlie rheumatoid arthritis (RA)-associated pain, and lysophosphatidic acid (LPA) is linked to both joint inflammation in RA patients and to neuropathic pain. Thus, we investigate
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b29dc2d42c562e763464fb315e36c2d0
https://www.hal.inserm.fr/inserm-03847767
https://www.hal.inserm.fr/inserm-03847767
Autor:
Anne-Marie Malfait, Richard J. Miller, Ada Delaney, S. Ishihara, Bula J. Bhattacharyya, Rachel E. Miller, Daniela M. Menichella
Publikováno v:
Arthritis & Rheumatology. 69:1429-1439
Objective To determine the ability of drugs that activate inhibitory G protein–coupled receptors (GPCRs) expressed in peripheral voltage-gated sodium channel 1.8 (NaV1.8)–positive sensory neurons to control osteoarthritis (OA)–associated pain.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a3cf7790ac56d66b131611fc8561e9b4
https://doi.org/10.1002/art.40118
https://doi.org/10.1002/art.40118
Autor:
Andrew S.C. Rice, Camilla I. Svensson, Rosie Morland, Anton Pekcec, Natalie J. Gardiner, Marcin Ligocki, Sabrina Voß, Ada Delaney, Thomas Christoph, Luke A. Bryden, Carina Stenfors, Rolf-Detlef Treede, Ian Machin, Kris Rutten, Camilla Ultenius, Katsuhiro Uto, A. Robens, Ombretta Caspani, Nick Andrews, Annika Lindsten, Dominic L. Li, Kazumi Yamamoto, Suguru Koyama, Wenlong Huang, Märta Segerdahl, Jeffrey D. Kennedy, Rachel Wodarski, Catherine Baastrup, Sanziana M. Rotariu
Publikováno v:
Wodarski, R, Delaney, A, Ultenius, C, Morland, R, Andrews, N, Baastrup, C, Bryden, L, Caspani, O, Christoph, T, Gardiner, N, Huang, W, Kennedy, J D, Koyama, S, Li, D, Ligocki, M, Lindsten, A, Machin, I, Pekcec, A, Robens, A, Rotariu, S M, Voss, S, Segerdahl, M, Stenfors, C, Svensson, C I, Treede, R-D, Uto, K, Yamamoto, K, Rutten, K & Rice, A S C 2016, ' Cross-centre replication of suppressed burrowing behaviour as an ethologically relevant pain outcome measure in the rat: a prospective multicentre study ', Pain, vol. 157, no. 10, pp. 2350-2365 . https://doi.org/10.1097/j.pain.0000000000000657
Pain
Pain
Supplemental Digital Content is Available in the Text. This unique multicenter approach provides high-quality evidence validating burrowing as a robust and reproducible outcome measure to infer the global effect of pain on rodents.
Burrowing, an
Burrowing, an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cc1d6c95f6a58ea33fb9e6c5da41af5f
https://doi.org/10.1097/j.pain.0000000000000657
https://doi.org/10.1097/j.pain.0000000000000657
Autor:
Anthony H. Dickenson, Lesley Colvin, Gillian L. Currie, Ada Delaney, Emily S. Sena, Malcolm R. Macleod, Michael I. Bennett, Hanna M. Vesterinen, Kieren J. Egan, Marie Fallon
Publikováno v:
Pain. 154:917-926
Pain can significantly decrease the quality of life of patients with advanced cancer. Current treatment strategies often provide inadequate analgesia and unacceptable side effects. Animal models of bone cancer pain are used in the development of nove
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dc8defe678a560ec10a6ac7678cd7459
https://doi.org/10.1016/j.pain.2013.02.033
https://doi.org/10.1016/j.pain.2013.02.033
Autor:
Rachel E, Miller, Shingo, Ishihara, Bula, Bhattacharyya, Ada, Delaney, Daniela M, Menichella, Richard J, Miller, Anne-Marie, Malfait
Publikováno v:
Arthritisrheumatology (Hoboken, N.J.). 69(7)
To determine the ability of drugs that activate inhibitory G protein-coupled receptors (GPCRs) expressed in peripheral voltage-gated sodium channel 1.8 (NaWe used designer receptors exclusively activated by a designer drug (DREADD) technology, which
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::9f530c54b852f1e0e110822addbf0513
https://pubmed.ncbi.nlm.nih.gov/28435151
https://pubmed.ncbi.nlm.nih.gov/28435151
Autor:
Diana Kadetoff, Anna Nordenstedt Agréus, Tony L. Yaksh, Eva Kosek, Maripat Corr, Marie Westman, Ada Delaney, Jon Lampa, Mohsen Khademi, Christina A. Christianson, Erwan Le Maître, Camilla I. Svensson, Caroline Gillis-Haegerstrand, Magnus Andersson
Publikováno v:
Proceedings of the National Academy of Sciences. 109:12728-12733
During peripheral immune activation caused by an infection or an inflammatory condition, the innate immune response signals to the brain and causes an up-regulation of central nervous system (CNS) cytokine production. Central actions of proinflammato
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2051fc45bb9e76a968314a666bdeb689
https://doi.org/10.1073/pnas.1118748109
https://doi.org/10.1073/pnas.1118748109
Autor:
Marcelo P. Coba, Noboru H. Komiyama, Holly J. Carlisle, Andrew Allchorne, Matthew Bence, Susan M. Fleetwood-Walker, Emer M. Garry, Roberta Rosie, Ada Delaney, Margaret I. Arbuckle, Thomas J. O'Dell, Seth G. N. Grant, Rory Mitchell, Lynsey H Forsyth
Publikováno v:
EMBO Reports
Arbuckle, M I, Komiyama, N H, Delaney, A, Coba, M, Garry, E M, Rosie, R, Allchorne, A J, Forsyth, L H, Bence, M, Carlisle, H J, O'Dell, T J, Mitchell, R, Fleetwood-Walker, S M & Grant, S 2010, ' The SH3 domain of postsynaptic density 95 mediates inflammatory pain through phosphatidylinositol-3-kinase recruitment ', EMBO Reports, vol. 11, no. 6, pp. 473-478 . https://doi.org/10.1038/embor.2010.63
Arbuckle, M I, Komiyama, N H, Delaney, A, Coba, M, Garry, E M, Rosie, R, Allchorne, A J, Forsyth, L H, Bence, M, Carlisle, H J, O'Dell, T J, Mitchell, R, Fleetwood-Walker, S M & Grant, S 2010, ' The SH3 domain of postsynaptic density 95 mediates inflammatory pain through phosphatidylinositol-3-kinase recruitment ', EMBO Reports, vol. 11, no. 6, pp. 473-478 . https://doi.org/10.1038/embor.2010.63
The SH3 domain of postsynaptic density 95 mediates inflammatory pain through phosphatidylinositol-3-kinase recruitment Sensitization to inflammatory pain is a pathological form of neuronal plasticity that is poorly understood and treated. Here the au
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fd92d18de50af7502e74332d4a56e719
http://europepmc.org/articles/PMC2892321
http://europepmc.org/articles/PMC2892321
Autor:
Elspeth Milne, Darren C. Robertson, Darren J. Shaw, Eva C. Sirinathsinghji, Anisha Patel, Emma Jones, Heather Anderson, Rachel A. Eager, Joe Mayhew, Ada Delaney, Andrew Allchorne, Ignacio Viñuela-Fernández, Natalie Waran, Susan M. Fleetwood-Walker, Neil Macintyre
Publikováno v:
Jones, E, Vinuela-Fernandez, N, Eager, R A, Delaney, A, Anderson, H, Patel, A, Robertson, D C, Allchorne, A, Sirinathsinghji, E C, Milne, E M, Macintyre, N, Shaw, D J, Waran, N K, Mayhew, J & Fleetwood-Walker, S M 2007, ' Neuropathic changes in equine laminitis pain ', Pain, vol. 132, no. 3, pp. 321-31 . https://doi.org/10.1016/j.pain.2007.08.035
Laminitis is a common debilitating disease in horses that involves painful disruption of the lamellar dermo-epidermal junction within the hoof. This condition is often refractory to conventional anti-inflammatory analgesia and results in unremitting
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::423288f32889d67d614a58afffdbde8f
https://doi.org/10.1016/j.pain.2007.08.035
https://doi.org/10.1016/j.pain.2007.08.035
Autor:
Christine Walsh, Aileen M. Lynch, Ada Delaney, Yvonne M. Nolan, Veronica A. Campbell, Marina A. Lynch
Publikováno v:
Journal of Neurochemistry. 88:635-646
Parenterally administered lipopolysaccharide (LPS) increases the concentration of the pro-inflammatory cytokine interleukin-1beta (IL-1beta) in the rat hippocampus and evidence suggests that this effect plays a significant role in inhibiting long-ter
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::158a8ad87b11e76920689fa5e073e742
https://doi.org/10.1046/j.1471-4159.2003.02157.x
https://doi.org/10.1046/j.1471-4159.2003.02157.x