Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Ada Congrains"'
Autor:
Rubia Isler Mancuso, Juliana Hofstätter Azambuja, Fernanda Soares Niemann, Ada Congrains, Mary Ann Foglio, Eduardo Magalhães Rego, Sara Teresinha Olalla Saad
Publikováno v:
eJHaem, Vol 2, Iss 4, Pp 818-822 (2021)
Abstract Loss of endoplasmic reticulum (ER) homeostasis leads to ER stress, thus prolonged activation can lead to apoptosis. Herein, artesunate (ART) induced ER stress in leukaemia cells, resulting in eIF2α phosphorylation, activation of transcripti
Externí odkaz:
https://doaj.org/article/3888e08a0ce64834bc977e962c16f173
Autor:
Ada Congrains, Fernanda Soares Niemann, Adriana Da Silva Santos Duarte, Karla Priscila Vieira Ferro, Sara Teresinha Olalla-Saad
Publikováno v:
Frontiers in Oncology, Vol 10 (2020)
NR4A3 is a key tumor suppressor in myeloid malignancy, mice lacking both NR4A1 and family member NR4A3 rapidly develop lethal acute myeloid leukemia (AML). We identified a long non-coding transcript in the NR4A3 locus and pursued the characterization
Externí odkaz:
https://doaj.org/article/4de670433f9942dea3142659e2e70f72
Publikováno v:
Materials, Vol 14, Iss 3, p 569 (2021)
Hematopoietic stem cells (HSC) are responsible for the production of blood and immune cells during life. HSC fate decisions are dependent on signals from specialized microenvironments in the bone marrow, termed niches. The HSC niche is a tridimension
Externí odkaz:
https://doaj.org/article/4525aee63a774bd2bb7ad417384ccc5c
Publikováno v:
International Journal of Molecular Sciences, Vol 14, Iss 1, Pp 1278-1292 (2013)
ANRIL is a recently discovered long non-coding RNA encoded in the chromosome 9p21 region. This locus is a hotspot for disease-associated polymorphisms, and it has been consistently associated with cardiovascular disease, and more recently with severa
Externí odkaz:
https://doaj.org/article/b5ef29cfeec147d280cccb98bb618299
Autor:
Mary Ann Foglio, Fernanda Soares Niemann, Eduardo Magalhães Rego, Rubia Isler Mancuso, Sara Teresinha Olalla Saad, Juliana Hofstatter Azambuja, Ada Congrains
Publikováno v:
eJHaem. 2:818-822
Loss of endoplasmic reticulum (ER) homeostasis leads to ER stress, thus prolonged activation can lead to apoptosis. Herein, artesunate (ART) induced ER stress in leukaemia cells, resulting in eIF2α phosphorylation, activation of transcription factor
Autor:
Sara Teresinha Olalla Saad, Joanna F. Weber, Renata Giardini Rosa, Paulo Pinto Joazeiro, Stephen D. Waldman, Juares Bianco, Ada Congrains-Castillo
Publikováno v:
Biomaterials Science. 7:1516-1528
Due to the increasing demand for a bone marrow study model, we developed a natural scaffold from decellularized bovine bone marrow (DeBM). The obtained bioscaffold was analyzed after the decellularization process; histological staining, scanning and
Autor:
Sara T. Olalla-Saad, Fernanda Soares Niemann, Ada Congrains, Karla Priscila Ferro, Adriana S. S. Duarte
Publikováno v:
Frontiers in Oncology
Frontiers in Oncology, Vol 10 (2020)
Frontiers in Oncology, Vol 10 (2020)
NR4A3 is a key tumor suppressor in myeloid malignancy, mice lacking both NR4A1 and family member NR4A3 rapidly develop lethal acute myeloid leukemia (AML). We identified a long non-coding transcript in the NR4A3 locus and pursued the characterization
Publikováno v:
Materials, Vol 14, Iss 569, p 569 (2021)
Materials
Materials
Hematopoietic stem cells (HSC) are responsible for the production of blood and immune cells during life. HSC fate decisions are dependent on signals from specialized microenvironments in the bone marrow, termed niches. The HSC niche is a tridimension
Publikováno v:
Journal of Cellular and Molecular Medicine
LEF1 antisense RNA 1 (LEF1‐AS1) is an antisense long non‐coding RNA encoded in the lymphoid enhancer‐binding factor 1 (LEF1) locus. LEF1‐AS1 is a conserved transcript dysregulated in hematopoiesis. This study aimed to functionally characteriz
Autor:
Kazunori Ikebe, Yasuyuki Gondo, Hiromi Rakugi, Yuki Imaizumi, Hiroshi Kusunoki, Yasumichi Arai, Shigeyuki Saitoh, Yasushi Takeya, Nobuhisa Awata, Miyuki Onishi-Takeya, Tomohiro Katsuya, Tetsuji Miura, Hiroshi Akasaka, Ryousuke Oguro, Kei Kamide, Ada Congrains, Norihiro Kato, Nobuyoshi Hirose, Koichi Yamamoto, Hiroko Yamamoto, Tatsuo Kawai, Ken Sugimoto, Chikako Nakama
Publikováno v:
Geriatrics & Gerontology International. 15:797-803
Aim The 9p21 region has been pointed out by the genome-wide association studies as a hot spot for disease-associated variants. Most of the diseases linked with the locus are aging-related conditions, such us cardiovascular disease, diabetes and cance