Zobrazeno 1 - 10
of 117
pro vyhledávání: '"Ada, Keding"'
Autor:
Charlie Welch, Martin Forster, Sarah Ronaldson, Ada Keding, Belen Corbacho-Martín, Puvan Tharmanathan
Publikováno v:
BMC Medical Research Methodology, Vol 24, Iss 1, Pp 1-18 (2024)
Abstract Background There is increasing interest in the capacity of adaptive designs to improve the efficiency of clinical trials. However, relatively little work has investigated how economic considerations – including the costs of the trial – m
Externí odkaz:
https://doaj.org/article/dd023476b87c4726874a981f718a04b9
Autor:
Qi Wu, Catriona McDaid, Avril Drummond, Toby O Smith, Ira Madan, Mike Reed, Joy Adamson, Ada Keding, Paul Baker, Lucksy Kottam, Louise Thomson, Lesley Sinclair, David A McDonald, Ann Hewison, Gill Parkinson, Lucy Sheehan, Amie Woodward, Marion Archer, Carol Jordan, Maisie Martland, Lou Watkins
Publikováno v:
BMJ Open, Vol 14, Iss 9 (2024)
Background In the UK, one in four patients are in work at the time of their hip or knee replacement surgery. These patients receive little support about their return to work (RTW). There is a need for an occupational support intervention that encoura
Externí odkaz:
https://doaj.org/article/45783fe0b8f1499082fda226d569df74
Autor:
Brima M. Younis, Rebecca Wiggins, Eltahir A.G. Khalil, Mohamed Osman, Francesco Santoro, Chiara Sonnati, Ada Keding, Maria Novedrati, Giorgio Montesi, Ali Noureldein, Elmukashfi T.A. Elmukashfi, Ala Eldin Mustafa, Mohammed Alamin, Mohammed Saeed, Khalid Salman, Ahmed J. Suliman, Amin E.A. Musa, Alison M. Layton, Charles J.N. Lacey, Paul M. Kaye, Ahmed M. Musa
Publikováno v:
Molecular Therapy: Methods & Clinical Development, Vol 32, Iss 3, Pp 101310- (2024)
In a recent phase 2a clinical trial, the candidate leishmaniasis vaccine ChAd63-KH was shown to be safe and immunogenic in Sudanese patients with post kala-azar dermal leishmaniasis (PKDL). However, its value as a stand-alone therapeutic was unknown.
Externí odkaz:
https://doaj.org/article/a583923d15cf4d3cb40a6f85f30978df
Autor:
Amar Rangan, Stephen Gwilym, Ada Keding, Belen Corbacho, Lucksy Kottam, Catherine Arundel, Elizabeth Coleman, Livio DiMascio, Catherine Hewitt, Valerie Jones, Jamila Kassam, Catriona McDaid, Natasha Mitchell, Andrew Mott, Grace O’Carroll, Puvan Tharmanathan, David Torgerson
Publikováno v:
Trials, Vol 24, Iss 1, Pp 1-14 (2023)
Abstract Background Proximal humerus fractures (PHF) are common and painful injuries, with the majority resulting from falls from a standing height. As with other fragility fractures, its age-specific incidence is increasing. Surgical treatment with
Externí odkaz:
https://doaj.org/article/79bc65264bc341e4954b3320674e877e
Publikováno v:
Bone & Joint Open, Vol 4, Iss 2, Pp 96-103 (2023)
Aims: Early large treatment effects can arise in small studies, which lessen as more data accumulate. This study aimed to retrospectively examine whether early treatment effects occurred for two multicentre orthopaedic randomized controlled trials (R
Externí odkaz:
https://doaj.org/article/33801a29243c473fafb2d990573eb9b5
Autor:
Carolyn A. Chew-Graham, Charlotte E. W. Kitchen, Samantha Gascoyne, Elizabeth Littlewood, Elizabeth Coleman, Della Bailey, Suzanne Crosland, Caroline Pearson, Shehzad Ali, Jay Badenhorst, Clare Bambra, Catherine Hewitt, Claire Jones, Ada Keding, Dean McMillan, Claire Sloan, Adam Todd, Paul Toner, Cate Whittlesea, Michelle Watson, Simon Gilbody, David Ekers
Publikováno v:
Pilot and Feasibility Studies, Vol 8, Iss 1, Pp 1-16 (2022)
Abstract Background Adults with long-term health conditions (LTCs) are more likely to experience depressive symptoms which can worsen health outcomes and quality of life, and increase healthcare costs. Subthreshold depression may go undetected and/or
Externí odkaz:
https://doaj.org/article/6e1894878d1e4db89178fdb1f6fa6c4a
Autor:
Saleema S. Rex, Lucksy Kottam, Catriona McDaid, Stephen Brealey, Joseph Dias, Catherine E. Hewitt, Ada Keding, Sarah E. Lamb, Kath Wright, Amar Rangan
Publikováno v:
Bone & Joint Open, Vol 2, Iss 9, Pp 773-784 (2021)
Aims: This systematic review places a recently completed multicentre randomized controlled trial (RCT), UK FROST, in the context of existing randomized evidence for the management of primary frozen shoulder. UK FROST compared the effectiveness of pre
Externí odkaz:
https://doaj.org/article/57e3820f135e4149a065ecbdd8a16e1d
Autor:
Joseph Dias, Catherine Arundel, Puvan Tharmanathan, Ada Keding, Charlie Welch, Belen Corbacho, Maria Armaou, Paul Leighton, Christopher Bainbridge, Michael Craigen, Lydia Flett, Samantha Gascoyne, Catherine Hewitt, Elaine James, Sophie James, Nick Johnson, Judy Jones, Catherine Knowlson, Priya Radia, David Torgerson, David Warwick, Michelle Watson
Publikováno v:
Trials, Vol 22, Iss 1, Pp 1-15 (2021)
Abstract Background Dupuytren’s contracture is a fibro-proliferative disease of the hands affecting over 2 million UK adults, particularly the white, male population. Surgery is the traditional treatment; however, recent studies have indicated that
Externí odkaz:
https://doaj.org/article/35f1d7bde79649d2b499e0f52a769fcc
Autor:
Belen Corbacho, Stephen Brealey, Ada Keding, Gerry Richardson, David Torgerson, Catherine Hewitt, Catriona McDaid, Amar Rangan, On behalf of the UK FROST trial team
Publikováno v:
Bone & Joint Open, Vol 2, Iss 8, Pp 685-695 (2021)
Aims: A pragmatic multicentre randomized controlled trial, UK FROzen Shoulder Trial (UK FROST), was conducted in the UK NHS comparing the cost-effectiveness of commonly used treatments for adults with primary frozen shoulder in secondary care. Method
Externí odkaz:
https://doaj.org/article/d6c96ad0cd1049c19554f2476f244509
Autor:
Ahmed Musa, Charles Lacey, Brima Younis, El Tahir Khalil, Rebecca Wiggins, Mohamed Osman, Paul Kaye, Ada Keding
Publikováno v:
Wellcome Open Research, Vol 7 (2022)
Background: The leishmaniases are neglected tropical diseases caused by various Leishmania parasite species transmitted by sand flies. They comprise a number of systemic and cutaneous syndromes including kala-azar (visceral leishmaniasis, VL), cutane
Externí odkaz:
https://doaj.org/article/3a086220845c426fa72c622d6cae7fad