Zobrazeno 1 - 10
of 24
pro vyhledávání: '"Ad Peijnenburg"'
Autor:
Annick D. van den Brand, Lola Bajard, Inger-Lise Steffensen, Anne Lise Brantsæter, Hubert A. A. M. Dirven, Jochem Louisse, Ad Peijnenburg, Sophie Ndaw, Alberto Mantovani, Barbara De Santis, Marcel J. B. Mengelers
Publikováno v:
Toxins, Vol 14, Iss 4, p 279 (2022)
Humans are chronically exposed to the mycotoxins deoxynivalenol (DON) and fumonisin B1 (FB1), as indicated by their widespread presence in foods and occasional exposure in the workplace. This exposure is confirmed by human biomonitoring (HBM) studies
Externí odkaz:
https://doaj.org/article/fa774ff9d18d40b5b6fd80b957ec9482
Autor:
Igor Parra Pessoa, José Joaquim Lopes Neto, Thiago Silva de Almeida, Davi Felipe Farias, Leonardo Rogério Vieira, Jackeline Lima de Medeiros, Aline Augusti Boligon, Ad Peijnenburg, Ivan Castelar, Ana Fontenele Urano Carvalho
Publikováno v:
Molecules, Vol 21, Iss 12, p 1755 (2016)
Studies have shown the benefit of antioxidants in the prevention or treatment of human diseases and promoted a growing interest in new sources of plant antioxidants for pharmacological use. This study aimed to add value to two underexploited wild pla
Externí odkaz:
https://doaj.org/article/4a9ad7d4543043d1a1e9583d688fc407
Autor:
Louise von Stechow, Ainhoa Ruiz-Aracama, Bob van de Water, Ad Peijnenburg, Erik Danen, Arjen Lommen
Publikováno v:
PLoS ONE, Vol 8, Iss 10, p e76476 (2013)
The chemotherapeutic compound, cisplatin causes various kinds of DNA lesions but also triggers other pertubations, such as ER and oxidative stress. We and others have shown that treatment of pluripotent stem cells with cisplatin causes a plethora of
Externí odkaz:
https://doaj.org/article/790b6b9894b74c379669e034e7c6175f
Autor:
Jochem Louisse, Styliani Fragki, Deborah Rijkers, Aafke Janssen, Bas van Dijk, Liz Leenders, Martijn Staats, Bas Bokkers, Marco Zeilmaker, Aldert Piersma, Mirjam Luijten, Ron Hoogenboom, Ad Peijnenburg
Publikováno v:
Archives of Toxicology 97 (2023) 4
Archives of Toxicology, 97(4), 1113-1131
Archives of Toxicology, 97(4), 1113-1131
Per- and polyfluoroalkyl substances (PFASs) are omnipresent and have been shown to induce a wide range of adverse health effects, including hepatotoxicity, developmental toxicity, and immunotoxicity. The aim of the present work was to assess whether
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8859491c25eb20ddd224dd6229a00df5
https://research.wur.nl/en/publications/determination-of-in-vitro-hepatotoxic-potencies-of-a-series-of-pe
https://research.wur.nl/en/publications/determination-of-in-vitro-hepatotoxic-potencies-of-a-series-of-pe
Autor:
Styliani Fragki, Jochem Louisse, Bas Bokkers, Mirjam Luijten, Ad Peijnenburg, Deborah Rijkers, Aldert H. Piersma, Marco J. Zeilmaker
Publikováno v:
Food and Chemical Toxicology, 172
Food and Chemical Toxicology 172 (2023)
Food and Chemical Toxicology 172 (2023)
Per: and polyfluoroalkyl substances (PFASs) have been associated with increased blood lipids in humans. Perfluorooctanoic acid (PFOA) has been also linked with elevated alanine transferase (ALT) serum levels in humans, and in rodents the liver is a m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1fa0a41c86adc2f070aaa2f07f7d1a82
https://pubmed.ncbi.nlm.nih.gov/36535450
https://pubmed.ncbi.nlm.nih.gov/36535450
Autor:
Ad Peijnenburg, Marja J. C. A. Van Eggermond, Sam J. P. Gobin, Rian Van den Berg, Barbara C. Godthelp, Jaak M. J. J. Vossen, Peter J. Van den Elsen
Publikováno v:
The Journal of Immunology. 163:794-801
MHC class II deficiency or bare lymphocyte syndrome is a severe combined immunodeficiency caused by defects in MHC-specific transcription factors. In the present study, we show that fibroblasts derived from a recently identified bare lymphocyte syndr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::715aca46a12bb281b257e97b8ffab384
https://doi.org/10.4049/jimmunol.163.2.794
https://doi.org/10.4049/jimmunol.163.2.794
Autor:
Ilhan Tezcan, Maarten J. D. van Tol, Jaak M. Vossen, Peter J. van den Elsen, Marja C.J.A. van Eggermond, Ad Peijnenburg, Stefaan van Lierde, Barbara C. Godthelp
Publikováno v:
Blood. 94:348-358
To study the effects of major histocompatibility complex (MHC) class II expression on T-cell development, we have investigated T-cell immune reconstitution in two MHC class II–deficiency patients after allogeneic bone marrow transplantation (allo-B
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7f17bd67a164734b32739a425bc463c1
https://doi.org/10.1182/blood.v94.1.348.413k05_348_358
https://doi.org/10.1182/blood.v94.1.348.413k05_348_358
Autor:
M. C. J. A. Van Eggermond, Ozden Sanal, Ad Peijnenburg, P.J. van den Elsen, Jaak M. Vossen, R. van den Berg
Publikováno v:
Immunogenetics. 49:338-345
Patients suffering from major histocompatibility complex (MHC) class II deficiency, a rare primary immunodeficiency, are characterized by a lack of MHC class II expression which is the result of defects in trans-acting factors. At least four compleme
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5eb450071c18e4e2b27e68a970b82406
https://doi.org/10.1007/s002510050501
https://doi.org/10.1007/s002510050501
Autor:
Rian van den Berg, Sam J. P. Gobin, Peter J. van den Elsen, Marlijn van Zutphen, Ad Peijnenburg, Marja C.J.A. van Eggermond
Publikováno v:
Immunity. 9(4):531-541
In type III bare lymphocyte syndrome (BLS) patients, defects in the RFX protein complex result in a lack of MHC class II and reduced MHC class I cell surface expression. Using type III BLS cell lines, we demonstrate that the RFX subunits RFX5 and RFX
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c7ca5c4ab8eccc9738a0e1594de61bda
Publikováno v:
Journal of immunotoxicology. 7(3)
The objective of this work was to investigate whether proteomic analysis of thymoma cells treated with the trichothecene deoxynivalenol (DON) as compared to non-treated (control) cells would reveal differential protein expression, and thus would cont
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::4aabde5ee99222d2c0f692ef84320b44
https://pubmed.ncbi.nlm.nih.gov/20672443
https://pubmed.ncbi.nlm.nih.gov/20672443