Výsledky vyhledávání - "Ad P. J. M. de Jong"

Quantitative Proteomics Reveals Distinct Differences in the Protein Content of Outer Membrane Vesicle Vaccines

Autor: Bas van de Waterbeemd, Ad P J M de Jong, Jeroen L. A. Pennings, Geert P M Mommen, René H. Wijffels, Leo A. van der Pol, Michel H.M. Eppink

Publikováno v: Journal of Proteome Research, 12, 1898-1908
Journal of Proteome Research 12 (2013)

At present, only vaccines containing outer membrane vesicles (OMV) have successfully stopped Neisseria meningitidis serogroup B epidemics. These vaccines however require detergent-extraction to remove endotoxin, which changes immunogenicity and cause

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b5d0afb0c45b833f3e3349dfe0b8623b
https://doi.org/10.1021/pr301208g

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Identifying the epitope-specific T cell response to virus infections

Autor: Cécile A. C. M. van Els, Ad P. J. M. de Jong, Ernst C. Soethout, Hugo D. Meiring

Publikováno v: Vaccine. 25:3200-3203

Virus infection induces an adaptive immune response by T cells that is specific for defined viral epitopes. The epitope-specific analysis of T cells has become an important tool for investigating the anti viral response following infection or vaccina

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a841a6b0b9e2cec67895879ddc183ae5
https://doi.org/10.1016/j.vaccine.2007.01.029

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Stable Isotope Tagging of Epitopes

Autor: Albert J. R. Heck, Claire J. P. Boog, Hugo D. Meiring, Ernst C. Soethout, Ronald Hoogerbrugge, Hans A. M. Timmermans, Cécile A. C. M. van Els, Martien C. M. Poelen, Ad P. J. M. de Jong, Dennis Mooibroek

Publikováno v: Molecular & Cellular Proteomics. 5:902-913

Identification of peptides presented in major histocompatibility complex (MHC) class I molecules after viral infection is of strategic importance for vaccine development. Until recently, mass spectrometric identification of virus-induced peptides was

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::76cbb3560014a199e9c16d902513d6d2
https://doi.org/10.1074/mcp.t500014-mcp200

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A single naturally processed measles virus peptide fully dominates the HLA-A*0201-associated peptide display and is mutated at its anchor position in persistent viral strains

Autor: Ad P. J. M. de Jong, Alexander van der Kooi, Ed van der Heeft, G. Jan ten Hove, Carla A. Herberts, Hugo D. Meiring, Cécile A. C. M. van Els, Martien C. M. Poelen, Jacqueline A. M. van Gaans-van den Brink, Peter Hoogerhout

Publikováno v: European Journal of Immunology. 30:1172-1181

We studied the natural MHC class I display of measles virus (MV) epitopes. Peptide ligands associated with HLA-A*0201 were purified from a B lymphoblastoid cell line prior to and after infection with MV. Infection-induced peptides were revealed using

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::aa0d2b847cbbe26c27f6741796c1b2e8
https://doi.org/10.1002/(sici)1521-4141(200004)30:4<1172::aid-immu1172>3.0.co

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A Microcapillary Column Switching HPLC−Electrospray Ionization MS System for the Direct Identification of Peptides Presented by Major Histocompatibility Complex Class I Molecules

Autor: G. Jan ten Hove, Hugo D. Meiring, Ad P. J. M. de Jong, Carla A. Herberts, and Cecile A. C. M. van Els, Ed van der Heeft

Publikováno v: Analytical Chemistry. 70:3742-3751

A microcapillary column switching high-performance liquid chromatography (HPLC) system was developed for the separation of major histocompatibility complex (MHC) class I associated peptides. Combination of the column switching system with electrospra

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a1e6a6d3b31205999d928c8f18d2b45d
https://doi.org/10.1021/ac9801014

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Unbiased Selective Isolation of Protein N-Terminal Peptides from Complex Proteome Samples Using Phospho Tagging PTAG) and TiO2-based Depletion

Autor: Ad P. J. M. de Jong, Geert P M Mommen, Hugo D. Meiring, Albert J. R. Heck, Gideon F.A. Kersten, Bas van de Waterbeemd

Publikováno v: Molecular and Cellular Proteomics 11 (2012) 9
Molecular and Cellular Proteomics, 11(9), 832-842

A positional proteomics strategy for global N-proteome analysis is presented based on phospho tagging (PTAG) of internal peptides followed by depletion by titanium dioxide (TiO2) affinity chromatography. Therefore, N-terminal and lysine amino groups

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9dad996aa06ef6b210239f93910a84ec
https://research.wur.nl/en/publications/unbiased-selective-isolation-of-protein-n-terminal-peptides-from-

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Exploring the human leukocyte phosphoproteome using a microfluidic reversed-phase-TiO2-reversed-phase high-performance liquid chromatography phosphochip coupled to a quadrupole time-of-flight mass spectrometer

Autor: Ad P. J. M. de Jong, Karsten Kraiczek, A.J.R. Heck, Reinout Raijmakers, Shabaz Mohammed

Publikováno v: Analytical chemistry. 82(3)

The study of protein phosphorylation events is one of the most important challenges in proteome analysis. Despite the importance of phosphorylation for many regulatory processes in cells and many years of phosphoprotein and phosphopeptide research, t

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8b72dc9677310c5f1d2d6dbc9147cdf7
https://pubmed.ncbi.nlm.nih.gov/20058876

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Stable isotope tagging of epitopes: a highly selective strategy for the identification of major histocompatibility complex class I-associated peptides induced upon viral infection

Autor: Hugo D, Meiring, Ernst C, Soethout, Martien C M, Poelen, Dennis, Mooibroek, Ronald, Hoogerbrugge, Hans, Timmermans, Claire J, Boog, Albert J R, Heck, Ad P J M, de Jong, Cécile A C M, van Els

Publikováno v: Molecularcellular proteomics : MCP. 5(5)

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::16410972504f9bf30b6a1fe620260d68
https://pubmed.ncbi.nlm.nih.gov/16432254

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Mass tag-assisted identification of naturally processed HLA class II-presented meningococcal peptides recognized by CD4+ T lymphocytes

Autor: Ad P. J. M. de Jong, Claire J. P. Boog, Betsy Kuipers, Jacqueline A. M. van Gaans-van den Brink, Humphrey F. Brugghe, Gino J E Baart, Cécile A. C. M. van Els, Martien C. M. Poelen, Joost van Schie, Hans A. M. Timmermans, Hugo D. Meiring

Publikováno v: Journal of immunology (Baltimore, Md. : 1950). 174(9)

The meningococcal class I outer membrane protein porin A plays an important role in the development of T cell-dependent protective immunity against meningococcal serogroup B infection and is therefore a major component of candidate meningococcal vacc

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::391f475b5e5ed7433d6350ed344eef19
https://pubmed.ncbi.nlm.nih.gov/15843563

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