Gene polymorphisms in African buffalo associated with susceptibility to bovine tuberculosis infection.

Autor: Nikki le Roex, Ad P Koets, Paul D van Helden, Eileen G Hoal

Publikováno v: PLoS ONE, Vol 8, Iss 5, p e64494 (2013)

Bovine tuberculosis (BTB) is a chronic, highly infectious disease that affects humans, cattle and numerous species of wildlife. In developing countries such as South Africa, the existence of extensive wildlife-human-livestock interfaces poses a signi

Externí odkaz: https://doaj.org/article/4638a737aaa441aa977b26fd325a02ef

Metabolomic changes in polyunsaturated fatty acids and eicosanoids as diagnostic biomarkers in Mycobacterium avium ssp. paratuberculosis (MAP)-inoculated Holstein–Friesian heifers

Autor: Emma N. Taylor, Manfred Beckmann, Glyn Hewinson, David Rooke, Luis A. J. Mur, Ad P. Koets

Publikováno v: Veterinary Research, Vol 53, Iss 1, Pp 1-13 (2022)

Abstract Mycobacterium avium subspecies paratuberculosis (MAP) is the causative organism of Johne’s disease, a chronic granulomatous enteritis of ruminants. We have previously used naturally MAP-infected heifer calves to document metabolomic change

Externí odkaz: https://doaj.org/article/f7807cdb194d40db8fc6f6d3039fd467

Efficacy of Phase I and Phase II Coxiella burnetii Bacterin Vaccines in a Pregnant Ewe Challenge Model

Autor: Sarah E. Williams-Macdonald, Mairi Mitchell, David Frew, Javier Palarea-Albaladejo, David Ewing, William T. Golde, David Longbottom, Alasdair J. Nisbet, Morag Livingstone, Clare M. Hamilton, Stephen F. Fitzgerald, Søren Buus, Emil Bach, Annemieke Dinkla, Hendrik-Jan Roest, Ad P. Koets, Tom N. McNeilly

Publikováno v: Vaccines, Vol 11, Iss 3, p 511 (2023)

The bacterium Coxiella burnetii can cause the disease Q-fever in a wide range of animal hosts. Ruminants, including sheep, are thought to play a pivotal role in the transmission of C. burnetii to humans; however, the only existing livestock vaccine,

Externí odkaz: https://doaj.org/article/aa3c2c8447b9405e9658bda2802a97a5

Isotype-specific Antibody Responses to Mycobacterium avium paratuberculosis Antigens Are Associated With the Use of Biologic Therapy in Inflammatory Bowel Disease

Autor: Behrooz Z. Alizadeh, Annemieke Dinkla, Coretta Van Leer-Buter, Lars Ravesloot, Tjasso Blokzijl, Harry van Goor, Gerard Dijkstra, Ad P. Koets, Marijn C. Visschedijk, Hendrik M. van Dullemen, Eleonora A. M. Festen, Kimberley W. J. van der Sloot, Rinse K. Weersma, Michiel Voskuil

Publikováno v: Journal of Crohn's and Colitis, 15(8), 1253-1263
Journal of Crohn's and Colitis, 15(8), 1253-1263. Oxford University Press
Journal of Crohn's and Colitis 15 (2021) 8

Background The role of Mycobacterium avium paratuberculosis [MAP] in inflammatory bowel disease [IBD], especially Crohn’s disease [CD] is controversial due conflicting results and lack of reproducibility and standardised tests. The current study fo

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5dbe7617bf1e72e4b51d4795be29e55a
https://doi.org/10.1093/ecco-jcc/jjaa263

Metabolomic changes in naturally map-infected holstein–friesian heifers indicate immunologically related biochemical reprogramming

Autor: Emma Taylor, Glyn Hewinson, Manfred Beckmann, Luis A. J. Mur, H. Vordermeier, Ad P. Koets, David Rooke, Bernardo Villarreal-Ramos

Publikováno v: Metabolites 11 (2021) 11
Metabolites; Volume 11; Issue 11; Pages: 727
Metabolites, 11(11), 1. MDPI Multidisciplinary Digital Publishing Institute
Metabolites, Vol 11, Iss 727, p 727 (2021)
Metabolites, 11(11)
Metabolites

Johne’s disease, caused by Mycobacterium avium subsp. paratuberculosis (MAP), causes weight loss, diarrhoea, and reduced milk yields in clinically infected cattle. Asymptomatic, subclinically infected cattle shed MAP bacteria but are frequently not

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::69da4b2eb29d145fee4f43bd546bd88b
https://research.wur.nl/en/publications/metabolomic-changes-in-naturally-map-infected-holsteinfriesian-he