Frailty is associated with in-hospital mortality in older hospitalised COVID-19 patients in the Netherlands: the COVID-OLD study

Autor: Roy Looman, Harmke A Polinder-Bos, Marielle H. Emmelot-Vonk, Esther M.M. van de Glind, Esther J. M. de Brouwer, Huub A.A.M. Maas, Jeannet C Bos, Ralph Vreeswijk, Barbara C. van Munster, Laura C. Blomaard, Linda M Kampschreur, Jessica M. van der Bol, Steffy W. Jansen, Liesbeth Hempenius, Hanna C. Willems, Marjolein A. Wijngaarden, Anke J Borgers, Jan Festen, Petra E. Spies, Dennis G Barten, Aisha M Salarbaks, Rosalinde A L Smits, Ad M Kamper, Cees van Nieuwkoop, Sarah H M Robben, Marlies E M Regtuijt, Geert Labots, Frederiek van den Bos, Raya E S Geels, Carolien M. J. van der Linden, Francesco U.S. Mattace-Raso, Henrike J. Schouten, Marre M M de Koning, Bas de Groot, Leanne B L E Oosterwijk, Simon P. Mooijaart, Jacinta A. Lucke, Caroline E. Wyers, Rikje Ruiter, Rachida el Moussaoui, Oscar J. de Vries, Suzanne C. van Dijk, Floor J. van Deudekom, Orla M Smit

Publikováno v: Age and Ageing
Age and Ageing, 50(3), 631-640. Oxford University Press
Age and ageing, 50(3), 631-640. Oxford University Press
Age and Ageing, 50(3), 631-640. Oxford UP

Background During the first wave of the coronavirus disease 2019 (COVID-19) pandemic, older patients had an increased risk of hospitalisation and death. Reports on the association of frailty with poor outcome have been conflicting. Objective The aim

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4321a40d9167d6bef00eb1569f6447c4
https://pubmed.ncbi.nlm.nih.gov/33951156

Efficacy and safety of haloperidol prophylaxis for delirium prevention in older medical and surgical at-risk patients acutely admitted to hospital through the emergency department: study protocol of a multicenter, randomised, double-blind, placebo-controlled clinical trial

Autor: Esther Kuipéri, Oscar J. de Vries, Astrid Verburg, Ad M Kamper, Pierre M. Bet, Karola de Graaf, Edmée J M Schrijver, Douwe Pons, Anne M Lagaay, Andrea Siegel, Sabine H.A. Diepeveen, Leo Boelaarts, Rob J. van Marum, Astrid M van Strien, Prabath W. B. Nanayakkara, Sander Anten, Peter M. van de Ven, Mark H. H. Kramer

Publikováno v: Schrijver, E J M, de Vries, O J, Verburg, A, de Graaf, K, Bet, P M, van de Ven, P M, Kamper, A M, Diepeveen, S H A, Anten, S, Siegel, A, Kuiperi, E, Lagaay, A M, van Marum, R J, van Strien, A M, Boelaarts, L, Pons, D, Kramer, M H H & Nanayakkara, P W B 2014, ' Efficacy and safety of haloperidol prophylaxis for delirium prevention in older medical and surgical at-risk patients acutely admitted to hospital through the emergency department: study protocol of a multicenter, randomised, double-blind, placebo-controlled clinical trial ', BMC Geriatrics, vol. 14, 96 . https://doi.org/10.1186/1471-2318-14-96
BMC Geriatrics, 14:96. BioMed Central
BMC Geriatrics

Background Delirium is associated with substantial morbidity and mortality rates in elderly hospitalised patients, and a growing problem due to increase in life expectancy. Implementation of standardised non-pharmacological delirium prevention strate

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3fb757d8b3195bd0bec5fdccbec8e1d0
https://research.vumc.nl/en/publications/822191a3-eb31-4e35-99bd-a766a0b1bd8c

Bezafibrate reduces heart rate and blood pressure in patients with hypertriglyceridemia

Autor: Iris J. A. M. Jonkers, Augustinus H. M. Smelt, Frits H.A.F. de Man, Marijke Frölich, Jan A. Gevers Leuven, Gerard J. Blauw, Arnoud van der Laarse, Ad M. Kamper

Publikováno v: Journal of hypertension. 19(4)

In hypertriglyceridemic patients, hypertension occurs frequently and may be associated with hyperinsulinemia and elevated plasma levels of free fatty acids (FFA). Besides the lipid-lowering effects, fibrates have been shown to reduce blood pressure i

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4e9ee90b833c3abdc2abaac4b3020906
https://pubmed.ncbi.nlm.nih.gov/11330868