Zobrazeno 1 - 10
of 59
pro vyhledávání: '"Ad, Pyle"'
Autor:
Nitzahn M, Truong B, Khoja S, Vega-Crespo A, Le C, Eliav A, Makris G, Ad, Pyle, Häberle J, Gerald Lipshutz
Publikováno v:
The Yale Journal of Biology and Medicine
Scopus-Elsevier
Europe PubMed Central
Scopus-Elsevier
Europe PubMed Central
CPS1 deficiency is an inborn error of metabolism caused by loss-of-function mutations in the CPS1 gene, catalyzing the initial reaction of the urea cycle. Deficiency typically leads to toxic levels of plasma ammonia, cerebral edema, coma, and death,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::a6aab934d7cbaff895d6bc594ede6967
http://europepmc.org/articles/PMC8686786
http://europepmc.org/articles/PMC8686786
Autor:
Hicks MR; Eli and Edythe Broad Center of Regenerative Medicine and Stem Cell Research, University of California, Los Angeles, CA, USA. mrhicks1@uci.edu.; Department of Microbiology, Immunology, and Molecular Genetics, University of California, Los Angeles, CA, USA. mrhicks1@uci.edu.; Physiology and Biophysics, University of California, Irvine, CA, USA. mrhicks1@uci.edu., Saleh KK; Eli and Edythe Broad Center of Regenerative Medicine and Stem Cell Research, University of California, Los Angeles, CA, USA.; Molecular, Cellular & Integrative Physiology Program, University of California, Los Angeles, CA, USA., Clock B; Physiology and Biophysics, University of California, Irvine, CA, USA., Gibbs DE; Eli and Edythe Broad Center of Regenerative Medicine and Stem Cell Research, University of California, Los Angeles, CA, USA.; Molecular Biology Institute, University of California, Los Angeles, CA, USA., Yang M; Department of Microbiology, Immunology, and Molecular Genetics, University of California, Los Angeles, CA, USA., Younesi S; Eli and Edythe Broad Center of Regenerative Medicine and Stem Cell Research, University of California, Los Angeles, CA, USA.; Department of Microbiology, Immunology, and Molecular Genetics, University of California, Los Angeles, CA, USA., Gane L; Department of Microbiology, Immunology, and Molecular Genetics, University of California, Los Angeles, CA, USA., Gutierrez-Garcia V; CIRM Bridges Program, California State University, Northridge, CA, USA., Xi H; Eli and Edythe Broad Center of Regenerative Medicine and Stem Cell Research, University of California, Los Angeles, CA, USA.; Department of Microbiology, Immunology, and Molecular Genetics, University of California, Los Angeles, CA, USA., Pyle AD; Eli and Edythe Broad Center of Regenerative Medicine and Stem Cell Research, University of California, Los Angeles, CA, USA. apyle@mednet.ucla.edu.; Department of Microbiology, Immunology, and Molecular Genetics, University of California, Los Angeles, CA, USA. apyle@mednet.ucla.edu.; Molecular Biology Institute, University of California, Los Angeles, CA, USA. apyle@mednet.ucla.edu.; Jonnson Comprehensive Cancer Center, University of California, Los Angeles, CA, USA. apyle@mednet.ucla.edu.
Publikováno v:
Nature cell biology [Nat Cell Biol] 2024 Feb; Vol. 26 (2), pp. 306.
Autor:
Romero MA; Department of Microbiology, Immunology and Molecular Genetics, Eli and Edythe Broad Center of Regenerative Medicine and Stem Cell Research, UCLA, Los Angeles, CA, USA., Pyle AD; Department of Microbiology, Immunology and Molecular Genetics, Eli and Edythe Broad Center of Regenerative Medicine and Stem Cell Research, UCLA, Los Angeles, CA, USA. Electronic address: APyle@mednet.ucla.edu.
Publikováno v:
Current opinion in genetics & development [Curr Opin Genet Dev] 2023 Dec; Vol. 83, pp. 102133. Date of Electronic Publication: 2023 Nov 09.
Autor:
Hicks MR; Eli and Edythe Broad Center of Regenerative Medicine and Stem Cell Research, University of California, Los Angeles, CA, USA. mrhicks1@uci.edu.; Department of Microbiology, Immunology, and Molecular Genetics, University of California, Los Angeles, CA, USA. mrhicks1@uci.edu.; Physiology and Biophysics, University of California, Irvine, CA, USA. mrhicks1@uci.edu., Saleh KK; Eli and Edythe Broad Center of Regenerative Medicine and Stem Cell Research, University of California, Los Angeles, CA, USA.; Molecular, Cellular & Integrative Physiology Program, University of California, Los Angeles, CA, USA., Clock B; Physiology and Biophysics, University of California, Irvine, CA, USA., Gibbs DE; Eli and Edythe Broad Center of Regenerative Medicine and Stem Cell Research, University of California, Los Angeles, CA, USA.; Molecular Biology Institute, University of California, Los Angeles, CA, USA., Yang M; Department of Microbiology, Immunology, and Molecular Genetics, University of California, Los Angeles, CA, USA., Younesi S; Eli and Edythe Broad Center of Regenerative Medicine and Stem Cell Research, University of California, Los Angeles, CA, USA.; Department of Microbiology, Immunology, and Molecular Genetics, University of California, Los Angeles, CA, USA., Gane L; Department of Microbiology, Immunology, and Molecular Genetics, University of California, Los Angeles, CA, USA., Gutierrez-Garcia V; CIRM Bridges Program, California State University, Northridge, CA, USA., Xi H; Eli and Edythe Broad Center of Regenerative Medicine and Stem Cell Research, University of California, Los Angeles, CA, USA.; Department of Microbiology, Immunology, and Molecular Genetics, University of California, Los Angeles, CA, USA., Pyle AD; Eli and Edythe Broad Center of Regenerative Medicine and Stem Cell Research, University of California, Los Angeles, CA, USA. apyle@mednet.ucla.edu.; Department of Microbiology, Immunology, and Molecular Genetics, University of California, Los Angeles, CA, USA. apyle@mednet.ucla.edu.; Molecular Biology Institute, University of California, Los Angeles, CA, USA. apyle@mednet.ucla.edu.; Jonnson Comprehensive Cancer Center, University of California, Los Angeles, CA, USA. apyle@mednet.ucla.edu.
Publikováno v:
Nature cell biology [Nat Cell Biol] 2023 Dec; Vol. 25 (12), pp. 1758-1773. Date of Electronic Publication: 2023 Nov 02.
Autor:
Hicks MR; Department of Microbiology, Immunology and Medical Genetics, David Geffen School of Medicine at UCLA, Los Angeles, CA, USA.; Eli and Eli and Edythe Broad Center of Regenerative Medicine and Stem Cell Research, Los Angeles, CA, USA.; Department of Physiology and Biophysics, University of California Irvine, Irvine, CA, USA., Liu X; Department of Medicine, David Geffen School of Medicine at UCLA, Los Angeles, CA, USA.; California Nanosystems Institute at UCLA, Los Angeles, CA, USA.; Zhejiang Cancer Hospital, Hangzhou Institute of Medicine (HIM), Chinese Academy of Sciences, Hangzhou, 310022, Zhejiang, China., Young CS; Department of Neurology, David Geffen School of Medicine at UCLA, Los Angeles, CA, USA.; MyoGene Bio, San Diego, CA, USA., Saleh K; Department of Microbiology, Immunology and Medical Genetics, David Geffen School of Medicine at UCLA, Los Angeles, CA, USA., Ji Y; Department of Medicine, David Geffen School of Medicine at UCLA, Los Angeles, CA, USA., Jiang J; Department of Medicine, David Geffen School of Medicine at UCLA, Los Angeles, CA, USA.; California Nanosystems Institute at UCLA, Los Angeles, CA, USA.; Zhejiang Cancer Hospital, Hangzhou Institute of Medicine (HIM), Chinese Academy of Sciences, Hangzhou, 310022, Zhejiang, China., Emami MR; Department of Neurology, David Geffen School of Medicine at UCLA, Los Angeles, CA, USA., Mokhonova E; Department of Neurology, David Geffen School of Medicine at UCLA, Los Angeles, CA, USA., Spencer MJ; Eli and Eli and Edythe Broad Center of Regenerative Medicine and Stem Cell Research, Los Angeles, CA, USA. MSpencer@mednet.ucla.edu.; Department of Neurology, David Geffen School of Medicine at UCLA, Los Angeles, CA, USA. MSpencer@mednet.ucla.edu., Meng H; Department of Medicine, David Geffen School of Medicine at UCLA, Los Angeles, CA, USA. mengh@nanoctr.cn.; California Nanosystems Institute at UCLA, Los Angeles, CA, USA. mengh@nanoctr.cn.; CAS Key Laboratory for Biomedical Effects of Nanomaterials and Nanosafety, National Center for Nanoscience and Technology, Beijing, China. mengh@nanoctr.cn., Pyle AD; Department of Microbiology, Immunology and Medical Genetics, David Geffen School of Medicine at UCLA, Los Angeles, CA, USA. apyle@mednet.ucla.edu.; Eli and Eli and Edythe Broad Center of Regenerative Medicine and Stem Cell Research, Los Angeles, CA, USA. apyle@mednet.ucla.edu.
Publikováno v:
Journal of nanobiotechnology [J Nanobiotechnology] 2023 Aug 29; Vol. 21 (1), pp. 303. Date of Electronic Publication: 2023 Aug 29.
Autor:
Jaime OG; Department of Physiology and Biophysics, School of Medicine, University of California, Irvine, Irvine, CA 92697, USA.; Sue and Bill Gross Stem Cell Research Center, University of California, Irvine, Irvine, CA 92697, USA., Arias J; Department of Physiology and Biophysics, School of Medicine, University of California, Irvine, Irvine, CA 92697, USA., Pavani S; Department of Physiology and Biophysics, School of Medicine, University of California, Irvine, Irvine, CA 92697, USA., Pyle AD; Microbiology, Immunology, and Molecular Genetics, University of California, Los Angeles, CA 90095, USA., Hicks MR; Department of Physiology and Biophysics, School of Medicine, University of California, Irvine, Irvine, CA 92697, USA.; Sue and Bill Gross Stem Cell Research Center, University of California, Irvine, Irvine, CA 92697, USA.
Publikováno v:
Development (Cambridge, England) [Development] 2023 Jul 15; Vol. 150 (14). Date of Electronic Publication: 2023 Jul 13.
Autor:
Emami MR; Department of Neurology, David Geffen School of Medicine, University of California, Los Angeles, Los Angeles, CA, USA., Espinoza A; Department of Human Genetics, University of California, Los Angeles, Los Angeles, CA, USA.; Department of Molecular, Cell and Developmental Biology, University of California, Los Angeles, Los Angeles, CA, USA.; Institute for Quantitative and Computational Biosciences - The Collaboratory, University of California, Los Angeles, Los Angeles, CA, USA., Young CS; MyoGene Bio, San Diego, CA, USA., Ma F; Division of Rheumatology, Department of Internal Medicine, University of Michigan, Ann Arbor, MI, USA., Farahat PK; Department of Physiology and Biophysics, University of California, Irvine, Irvine, CA, USA., Felgner PL; Department of Physiology and Biophysics, University of California, Irvine, Irvine, CA, USA., Chamberlain JS; Department of Neurology, University of Washington School of Medicine, Seattle, WA, USA.; Senator Paul D. Wellstone Muscular Dystrophy Specialized Research Center, University of Washington School of Medicine, Seattle, WA, USA.; Department of Biochemistry, University of Washington School of Medicine, Seattle, WA, USA.; Department of Medicine, University of Washington School of Medicine, Seattle, WA, USA., Xu X; Department of Anatomy and Neurobiology, School of Medicine, University of California, Irvine, Irvine, CA, USA., Pyle AD; Department of Microbiology, Immunology and Molecular Genetics, University of California, Los Angeles, Los Angeles, CA, USA.; Eli and Edythe Broad Center of Regenerative Medicine and Stem Cell Research, University of California, Los Angeles, Los Angeles, CA, USA., Pellegrini M; Department of Molecular, Cell and Developmental Biology, University of California, Los Angeles, Los Angeles, CA, USA.; Institute for Genomics and Proteomics, University of California, Los Angeles, Los Angeles, CA, USA., Villalta SA; Department of Physiology and Biophysics, University of California, Irvine, Irvine, CA, USA.; Institute of Immunology, University of California, Irvine, Irvine, CA, USA.; Department of Neurology, University of California, Irvine, Irvine, CA, USA., Spencer MJ; Department of Neurology, David Geffen School of Medicine, University of California, Los Angeles, Los Angeles, CA, USA.; Eli and Edythe Broad Center of Regenerative Medicine and Stem Cell Research, University of California, Los Angeles, Los Angeles, CA, USA.
Publikováno v:
Molecular therapy. Methods & clinical development [Mol Ther Methods Clin Dev] 2023 Jun 12; Vol. 30, pp. 90-102. Date of Electronic Publication: 2023 Jun 12 (Print Publication: 2023).
Autor:
Gibbs DE; Molecular Biology Institute, Department of Microbiology, Immunology and Molecular Genetics, Eli and Edythe Broad Center of Regenerative Medicine and Stem Cell Research, University of California, Los Angeles, Los Angeles, CA 90095, USA., Pyle AD; Molecular Biology Institute, Department of Microbiology, Immunology and Molecular Genetics, Eli and Edythe Broad Center of Regenerative Medicine and Stem Cell Research, University of California, Los Angeles, Los Angeles, CA 90095, USA. Electronic address: apyle@mednet.ucla.edu.
Publikováno v:
Cell [Cell] 2023 May 11; Vol. 186 (10), pp. 2041-2043.
Autor:
Saleh KK; Department of Microbiology, Immunology and Molecular Genetics, University of California Los Angeles, Los Angeles, CA, United States.; Eli and Edythe Broad Center of Regenerative Medicine and Stem Cell Research, University of California Los Angeles, Los Angeles, CA, United States., Switzler C; Department of Microbiology, Immunology and Molecular Genetics, University of California Los Angeles, Los Angeles, CA, United States., Hicks MR; Department of Microbiology, Immunology and Molecular Genetics, University of California Los Angeles, Los Angeles, CA, United States.; Eli and Edythe Broad Center of Regenerative Medicine and Stem Cell Research, University of California Los Angeles, Los Angeles, CA, United States., Gane L; Department of Microbiology, Immunology and Molecular Genetics, University of California Los Angeles, Los Angeles, CA, United States.; Eli and Edythe Broad Center of Regenerative Medicine and Stem Cell Research, University of California Los Angeles, Los Angeles, CA, United States., Gibbs DE; Department of Microbiology, Immunology and Molecular Genetics, University of California Los Angeles, Los Angeles, CA, United States.; Eli and Edythe Broad Center of Regenerative Medicine and Stem Cell Research, University of California Los Angeles, Los Angeles, CA, United States.; Molecular Biology Institute, University of California Los Angeles, Los Angeles, CA, United States., Pyle AD; Department of Microbiology, Immunology and Molecular Genetics, University of California Los Angeles, Los Angeles, CA, United States.; Eli and Edythe Broad Center of Regenerative Medicine and Stem Cell Research, University of California Los Angeles, Los Angeles, CA, United States.; Molecular Biology Institute, University of California Los Angeles, Los Angeles, CA, United States.
Publikováno v:
Frontiers in physiology [Front Physiol] 2023 May 09; Vol. 14, pp. 1190524. Date of Electronic Publication: 2023 May 09 (Print Publication: 2023).
Autor:
Stearns-Reider KM; Department of Integrative Biology and Physiology, University of California, Los Angeles, Los Angeles, CA, 90095, USA.; Department of Orthopaedic Surgery, David Geffen School of Medicine, University of California, Los Angeles, Los Angeles, CA, 90095, USA., Hicks MR; Department of Microbiology, Immunology, and Molecular Genetics, David Geffen School of Medicine, University of California, Los Angeles, Los Angeles, CA, 90095, USA.; Eli and Edythe Broad Center of Regenerative Medicine and Stem Cell Research, University of California, Los Angeles, Los Angeles, CA, 90095, USA.; Department of Physiology and Biophysics, University of California, Irvine, Irvine, CA, 92697, USA., Hammond KG; Department of Integrative Biology and Physiology, University of California, Los Angeles, Los Angeles, CA, 90095, USA., Reynolds JC; Department of Integrative Biology and Physiology, University of California, Los Angeles, Los Angeles, CA, 90095, USA., Maity A; Department of Integrative Biology and Physiology, University of California, Los Angeles, Los Angeles, CA, 90095, USA.; Department of Chemistry and Biochemistry, University of California, Los Angeles, Los Angeles, CA, 90095, USA.; Institute for Quantitative and Computational Biology, University of California, Los Angeles, Los Angeles, CA, 90095, USA., Kurmangaliyev YZ; Institute for Quantitative and Computational Biology, University of California, Los Angeles, Los Angeles, CA, 90095, USA.; Department of Biological Chemistry, HHMI, David Geffen School of Medicine, University of California, Los Angeles, Los Angeles, CA, 90095, USA., Chin J; Department of Integrative Biology and Physiology, University of California, Los Angeles, Los Angeles, CA, 90095, USA., Stieg AZ; California NanoSystems Institute, University of California, Los Angeles, Los Angeles, CA, 90095, USA., Geisse NA; Curi Bio, Seattle, WA, 98121, USA., Hohlbauch S; Asylum Research, An Oxford Instruments Company, Santa Barbara, CA, 93117, USA., Kaemmer S; Park Systems, 3040 Olcott St, Santa Clara, CA, 95054, USA., Schmitt LR; Department of Biochemistry and Molecular Genetics, University of Colorado, Denver, Aurora, CO, 80045, USA., Pham TT; Department of Biochemistry and Molecular Genetics, University of Colorado, Denver, Aurora, CO, 80045, USA., Yamauchi K; Eli and Edythe Broad Center of Regenerative Medicine and Stem Cell Research, University of California, Los Angeles, Los Angeles, CA, 90095, USA.; Department of Neurobiology, David Geffen School of Medicine, University of California, Los Angeles, Los Angeles, CA, 90095, USA., Novitch BG; Eli and Edythe Broad Center of Regenerative Medicine and Stem Cell Research, University of California, Los Angeles, Los Angeles, CA, 90095, USA.; Department of Neurobiology, David Geffen School of Medicine, University of California, Los Angeles, Los Angeles, CA, 90095, USA.; Molecular Biology Institute, University of California, Los Angeles, Los Angeles, CA, 90095, USA.; Intellectual and Developmental Disabilities Research Center, David Geffen School of Medicine, University of California Los Angeles, Los Angeles, CA, 90095, USA., Wollman R; Department of Integrative Biology and Physiology, University of California, Los Angeles, Los Angeles, CA, 90095, USA.; Department of Chemistry and Biochemistry, University of California, Los Angeles, Los Angeles, CA, 90095, USA.; Institute for Quantitative and Computational Biology, University of California, Los Angeles, Los Angeles, CA, 90095, USA., Hansen KC; Department of Biochemistry and Molecular Genetics, University of Colorado, Denver, Aurora, CO, 80045, USA., Pyle AD; Department of Microbiology, Immunology, and Molecular Genetics, David Geffen School of Medicine, University of California, Los Angeles, Los Angeles, CA, 90095, USA.; Eli and Edythe Broad Center of Regenerative Medicine and Stem Cell Research, University of California, Los Angeles, Los Angeles, CA, 90095, USA.; Molecular Biology Institute, University of California, Los Angeles, Los Angeles, CA, 90095, USA., Crosbie RH; Department of Integrative Biology and Physiology, University of California, Los Angeles, Los Angeles, CA, 90095, USA. rcrosbie@physci.ucla.edu.; Eli and Edythe Broad Center of Regenerative Medicine and Stem Cell Research, University of California, Los Angeles, Los Angeles, CA, 90095, USA. rcrosbie@physci.ucla.edu.; Molecular Biology Institute, University of California, Los Angeles, Los Angeles, CA, 90095, USA. rcrosbie@physci.ucla.edu.; Department of Neurology, David Geffen School of Medicine, University of California, Los Angeles, Los Angeles, CA, 90095, USA. rcrosbie@physci.ucla.edu.
Publikováno v:
NPJ Regenerative medicine [NPJ Regen Med] 2023 Mar 15; Vol. 8 (1), pp. 16. Date of Electronic Publication: 2023 Mar 15.