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pro vyhledávání: '"Acuto, O."'
Akademický článek
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Autor:
Lanz, A-L, Masi, G, Porciello, N, Cohnen, A, Cipria, D, Prakaash, D, Bálint, Š, Raggiaschi, R, Galgano, D, Cole, DK, Lepore, M, Dushek, O, Dustin, ML, Sansom, MSP, Kalli, AC, Acuto, O
The mechanism of T cell antigen receptor (TCR-CD3) signaling remains elusive. Here, we identify mutations in the transmembrane region of TCRβ or CD3ζ that augment peptide T cell antigen receptor (pMHC)-induced signaling not explicable by enhanced l
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=core_ac_uk__::9e007c1516b18e255258b729d06cc430
https://eprints.whiterose.ac.uk/176171/1/1-s2.0-S2211124721007737-main.pdf
https://eprints.whiterose.ac.uk/176171/1/1-s2.0-S2211124721007737-main.pdf
Akademický článek
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The protein tyrosine kinase ZAP-70, which mediates T-cell antigen receptor (TCR) signalling, contains three distinct functional modules, two tandemly arranged SH2 domains, a kinase domain and a linker region (interdomain B) that connects them. ZAP-70
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::ff91da275ca492d35eec314e95da1fca
https://doi.org/10.1046/j.1432-1327.1999.00973.x
https://doi.org/10.1046/j.1432-1327.1999.00973.x
Recent studies using cloned antigen specific T lymphocytes and monoclonal antibodies directed at their various surface glycoprotein components have led to identification of the human T cell antigen receptor as a surface complex comprised of a clonoty
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::8a75e473ee031dcd3d5244c0351a43b2
https://ora.ox.ac.uk/objects/uuid:cb4c48ae-b364-49fd-87c5-97a90db79ce3
https://ora.ox.ac.uk/objects/uuid:cb4c48ae-b364-49fd-87c5-97a90db79ce3
Recent studies using cloned antigen-specific T lymphocytes and monoclonal antibodies directed at their various surface glycoprotein components have led to identification of the human T cell antigen receptor as a surface complex composed of a clonotyp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::bbbee5a77eec0335d7c4924e47df7c9d
https://ora.ox.ac.uk/objects/uuid:f161d994-a6d5-4ce8-9f2a-1d60594cb72b
https://ora.ox.ac.uk/objects/uuid:f161d994-a6d5-4ce8-9f2a-1d60594cb72b
Publikováno v:
Scopus-Elsevier
Recent studies using cloned antigen-specific T lymphocytes and monoclonal antibodies directed at their various surface glycoprotein components have led to identification of the human T cell antigen receptor as a surface complex comprised of a clonoty
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::496262db70c60348e56575c3a2063fc1
https://ora.ox.ac.uk/objects/uuid:a3785c25-572b-49c0-b6d8-2e778998c52d
https://ora.ox.ac.uk/objects/uuid:a3785c25-572b-49c0-b6d8-2e778998c52d
Lck activation during T cell signaling is still not completely understood. In order to study this regulation in more physiologic stimulation conditions, we used resting human peripheral blood CD4(+) lymphoblasts stimulated with SAg-loaded APC's. Here
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od______1064::bb0912ab53fc43c48866c8e31888f1c6
https://ora.ox.ac.uk/objects/uuid:0297dcae-c64b-47b3-abff-97408bc8b3cb
https://ora.ox.ac.uk/objects/uuid:0297dcae-c64b-47b3-abff-97408bc8b3cb