Zobrazeno 1 - 2
of 2
pro vyhledávání: '"Actomyosin / physiology"'
Autor:
Inês Mendes Pinto, Diana Machado, David Rosa, Ana Costa, Ana Catarina Costa, Paula Sampaio, Marko Lampe, Feng Quan Zhou, Cátia D. F. Lopes, Paulo Aguiar, Rita Pinto-Costa, Luis Pajuelo, Xuewei Wang, Boris Rubinstein, Mónica Mendes Sousa, Sara C. Sousa, António J. Pereira, José C. Mateus
Publikováno v:
eLife, Vol 9 (2020)
eLife
eLife
Neurons have a membrane periodic skeleton (MPS) composed of actin rings interconnected by spectrin. Here, combining chemical and genetic gain- and loss-of-function assays, we show that in rat hippocampal neurons the MPS is an actomyosin network that
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e20d137be9429c4b64183418c4883241
https://hdl.handle.net/10216/141444
https://hdl.handle.net/10216/141444
Autor:
Daniel R. Croft, Michael F. Olson, Owen J. Sansom, Nick Barker, Paul Timpson, June Munro, Jose Lopez, Valerie M. Weaver, Michael S. Samuel, Hans Clevers, Valerie G. Brunton, Ewald Schroder, Ewan J. McGhee, David Strachan, Kurt I. Anderson, Jing Zhou
Publikováno v:
Samuel, M S, Lopez, J I, McGhee, E J, Croft, D R, Strachan, D, Timpson, P, Munro, J, Schröder, E, Zhou, J, Brunton, V G, Barker, N, Clevers, H, Sansom, O J, Anderson, K I, Weaver, V M & Olson, M F 2011, ' Actomyosin-mediated cellular tension drives increased tissue stiffness and β-catenin activation to induce epidermal hyperplasia and tumor growth ', Cancer Cell, vol. 19, no. 6, pp. 776-91 . https://doi.org/10.1016/j.ccr.2011.05.008
Cancer Cell, 19(6), 776-791. Cell Press
Cancer Cell, 19(6), 776-791. Cell Press
Tumors and associated stroma manifest mechanical properties that promote cancer. Mechanosensation of tissue stiffness activates the Rho/ROCK pathway to increase actomyosin-mediated cellular tension to re-establish force equilibrium. To determine how
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8b3e51bfa1bd17b4ce0ab97c1da753a5
https://doi.org/10.1016/j.ccr.2011.05.008
https://doi.org/10.1016/j.ccr.2011.05.008
