Zobrazeno 1 - 10
of 40
pro vyhledávání: '"Active drug targeting"'
Publikováno v:
Saudi Pharmaceutical Journal, Vol 29, Iss 8, Pp 857-873 (2021)
Background: Cisplatin (CSP) is a potent anticancer drug widely used in treating glioblastoma multiforme (GBM). However, CSP's clinical efficacy in GBM contrasted with low therapeutic ratio, toxicity, and multidrug resistance (MDR). Therefore, we have
Externí odkaz:
https://doaj.org/article/7806c3aea30f493998dc6b7b2d59c3e7
Publikováno v:
Frontiers in Medical Technology, Vol 4 (2022)
Endothelial cell adhesion molecules have long been proposed as promising targets in many pathologies. Despite promising preclinical data, several efforts to develop small molecule inhibitors or monoclonal antibodies (mAbs) against cell adhesion molec
Externí odkaz:
https://doaj.org/article/65dbdea95e3c4030be47ca7a347e0801
Autor:
Mazen M. El-Hammadi, José L. Arias
Publikováno v:
Nanomaterials, Vol 12, Iss 3, p 354 (2022)
Therapeutics are habitually characterized by short plasma half-lives and little affinity for targeted cells. To overcome these challenges, nanoparticulate systems have entered into the disease arena. Poly(d,l-lactide-co-glycolide) (PLGA) is one of th
Externí odkaz:
https://doaj.org/article/6e68330e4b1e40038d001bb7603c0ed0
Autor:
Rosa Maria Iacobazzi, Ilaria Arduino, Roberta Di Fonte, Angela Assunta Lopedota, Simona Serratì, Giuseppe Racaniello, Viviana Bruno, Valentino Laquintana, Byung-Chul Lee, Nicola Silvestris, Francesco Leonetti, Nunzio Denora, Letizia Porcelli, Amalia Azzariti
Publikováno v:
Cancers, Vol 14, Iss 5, p 5 (2022)
Cancers; Volume 14; Issue 1; Pages: 5
Cancers
Cancers; Volume 14; Issue 1; Pages: 5
Cancers
Simple Summary This research suggests a new potential therapeutic approach to pancreatic ductal adenocarcinoma to improve drug effectiveness and overcome drug resistance. A double actively targeted gemcitabine delivery system, consisting of polymeric
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3e65e850951f61f0757d94df6ee50bd8
https://www.mdpi.com/2072-6694/14/1/5
https://www.mdpi.com/2072-6694/14/1/5
Autor:
Juan M. Galdopórpora, Camila Martinena, Ezequiel Bernabeu, Jennifer Riedel, Lucia Palmas, Ines Castangia, Maria Letizia Manca, Mariana Garcés, Juan Lázaro-Martinez, Maria Jimena Salgueiro, Pablo Evelson, Nancy Liliana Tateosian, Diego Andres Chiappetta, Marcela Analia Moretton
Publikováno v:
Pharmaceutics; Volume 14; Issue 5; Pages: 959
Among respiratory infections, tuberculosis was the second deadliest infectious disease in 2020 behind COVID-19. Inhalable nanocarriers offer the possibility of actively targeting anti-tuberculosis drugs to the lungs, especially to alveolar macrophage
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9b6720fb56285e586d7deab80ac64b47
https://pubmed.ncbi.nlm.nih.gov/35631546
https://pubmed.ncbi.nlm.nih.gov/35631546
Autor:
El-Hammadi, Mazen M., Arias, Jose L.
Therapeutics are habitually characterized by short plasma half-lives and little affinity for targeted cells. To overcome these challenges, nanoparticulate systems have entered into the disease arena. Poly( D,L-lactide-co-glycolide) (PLGA) is one of t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od______2636::3d5897d89186b7af75ea6bd598d8c0d3
https://hdl.handle.net/10668/21442
https://hdl.handle.net/10668/21442
Autor:
Michelli B. Antonow, Camila Franco, Willian Prado, Aline Beckenkamp, Gustavo P. Silveira, Andréia Buffon, Sílvia S. Guterres, Adriana R. Pohlmann
Publikováno v:
Nanomaterials, Vol 8, Iss 1, p 2 (2017)
Doxorubicin (Dox) clinical use is limited by dose-related cardiomyopathy, becoming more prevalent with increasing cumulative doses. Previously, we developed Dox-loaded lipid-core nanocapsules (Dox-LNC) and, in this study, we hypothesized that self-as
Externí odkaz:
https://doaj.org/article/9c0accd767d84d40bd06b3c9cc8ecf37
Akademický článek
Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
K zobrazení výsledku je třeba se přihlásit.
K zobrazení výsledku je třeba se přihlásit.
Akademický článek
Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
K zobrazení výsledku je třeba se přihlásit.
K zobrazení výsledku je třeba se přihlásit.
Akademický článek
Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
K zobrazení výsledku je třeba se přihlásit.
K zobrazení výsledku je třeba se přihlásit.