Nrf2-dependent persistent oxidative stress results in stress-induced vulnerability to depression

Autor: Jean-Jacques Benoliel, Christophe Bernard, C. Rivat, N. Doligez, Franck Brouillard, J. Molet, N. Cresto, Bouvier E, Kim Q. Do, Jan-Harry Cabungcal, Christel Becker, Damien Claverie

Publikováno v: Molecular psychiatry, vol. 22, no. 12, pp. 1701-1713
Molecular Psychiatry
Molecular Psychiatry, Nature Publishing Group, 2017, 22 (12), pp.1701-1713. ⟨10.1038/mp.2016.144⟩

Stressful life events produce a state of vulnerability to depression in some individuals. The mechanisms that contribute to vulnerability to depression remain poorly understood. A rat model of intense stress (social defeat (SD), first hit) produced v

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8c8e09be48d03fcdae9287e4c51714ba
https://serval.unil.ch/notice/serval:BIB_65FE79A8973A

Interaction Domains and Nuclear Targeting Signals in Subunits of the U2 Small Nuclear Ribonucleoprotein Particle-associated Splicing Factor SF3a

Autor: Angela Krämer, Fabio Ferfoglia, Flore Raleff, Ching-Jung Huang

Publikováno v: JOURNAL OF BIOLOGICAL CHEMISTRY
Journal of Biological Chemistry, Vol. 286, No 15 (2011) pp. 13106-14

Human splicing factor SF3a is a component of the mature U2 small nuclear ribonucleoprotein particle (snRNP) and its three subunits of 60 66 and 120 kDa are essential for splicing in vitro and in vivo. The SF3a heterotrimer forms in the cytoplasm and

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e2fd9597c8614f7120e95ea8c2f8d720

Hyperinvasive Meningococci Induce Intra-nuclear Cleavage of the NF-κB Protein p65/RelA by Meningococcal IgA Protease

Autor: Besbes, Anissa, Le Goff, Salomé, Antunes, Ana, Terrade, Aude, Hong, Eva, Giorgini, Dario, Taha, Muhamed-Kheir, Deghmane, Ala-Eddine, Gray-Owen, Scott

Publikováno v: PLoS Pathogens
PLoS Pathogens, Public Library of Science, 2015, 11 (8), pp.e1005078. ⟨10.1371/journal.ppat.1005078⟩
PLoS Pathogens, 2015, 11 (8), pp.e1005078. ⟨10.1371/journal.ppat.1005078⟩
PLoS Pathogens, Vol 11, Iss 8, p e1005078 (2015)

Differential modulation of NF-κB during meningococcal infection is critical in innate immune response to meningococcal disease. Non-invasive isolates of Neisseria meningitidis provoke a sustained NF-κB activation in epithelial cells. However, the h

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3833973db5e0f427f7b892b1a1c03e58
https://hal-pasteur.archives-ouvertes.fr/pasteur-02013264/document

Nuclear export of mRNA

Autor: Françoise Stutz, Daniel Zenklusen

Publikováno v: FEBS Letters, Vol. 498, No 2-3 (2001) pp. 150-6

Export of mRNA through nuclear pore complexes (NPC) is preceded by multiple and well coordinated processing steps, resulting in the formation of an export competent ribonucleoprotein complex (mRNP). Numerous factors involved in the translocation of t

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a3187f0c0ba31b1fac44959f4bba45d0
https://doi.org/10.1016/s0014-5793(01)02482-6

In silico modulation of HMGN-1 binding to histones and gene expression by interplay of phosphorylation and O-GlcNAc modification

Autor: null Nasir-ud-Din, Ishtiaq Ahmad, Tehmina S. Khan, Daniel C. Hoessli, Evelyne Walker-Nasir, Afshan Kaleem, Abdul R. Shakoori

Publikováno v: Protein and Peptide Letters, Vol. 15, No 2 (2008) pp. 193-9

Utilizing different computational methods; phosphorylation, O-GlcNAc modification and Yin Yang sites are predicted in HMGN-1. Prediction results suggest that interplay of phosphorylation and O-GlcNAc modification regulates binding and removal of HMGN

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a6d21de467de23f7ec09ab480bd10b54
https://archive-ouverte.unige.ch/unige:2492