Zobrazeno 1 - 10
of 339
pro vyhledávání: '"Activated T cell"'
Publikováno v:
Frontiers in Physiology, Vol 15 (2024)
Externí odkaz:
https://doaj.org/article/9230e598ca004b53a8f4713f4a6c5e7b
Autor:
Lei Zhang, Huan-Huan Liu, Fan Yang, Zhi-Yuan Zhang, Ying Wu, Feng Li, Shi-Peng Dang, Zhen-Ye Zhang, Ling-Ling Qian, Ru-Xing Wang
Publikováno v:
BMC Cardiovascular Disorders, Vol 23, Iss 1, Pp 1-9 (2023)
Abstract Background Diabetes is associated with myocardial fibrosis, while the underlying mechanisms remain elusive. The aim of this study is to investigate the underlying role of calcineurin/nuclear factor of activated T cell 3 (CaN/NFATc3) pathway
Externí odkaz:
https://doaj.org/article/fc4fd511b00849b8b1c6d04b85abef3c
Publikováno v:
Clinical and Experimental Hypertension, Vol 0, Iss 0, Pp 1-12 (2022)
Background The present study aimed to investigate the effect of microRNA153 (miRNA153) on pulmonary hypertension (PH). Methods PH was induced by a single subcutaneous injection of sugen5416 (SU5416) combined with hypoxia exposure for 3 weeks (SuHx) i
Externí odkaz:
https://doaj.org/article/55830b17825345b48b925e013ecdd78d
Akademický článek
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Autor:
Jinchun Liu, Shunhua Peng, Lisha Ye, Yechao Sun, Qiong Zhao, Hua Wei, Qianqian Luo, Min He, Guohua Wang
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 17 (2023)
Traumatic brain injury (TBI) is one of the main causes of disability and death, especially in plateau areas, where the degree of injury is often more serious than in plain areas. It is likely that high altitude (HA) aggravates neuroinflammation; howe
Externí odkaz:
https://doaj.org/article/9569538712de401693315a2dd66092bd
Autor:
Yi-Fang Yang, Chuang-Ming Wang, I.-Hsin Hsiao, Yi-Liang Liu, Wen-Hao Lin, Chih-Li Lin, Hui-Chih Hung, Guang-Yaw Liu
Publikováno v:
Cellular & Molecular Biology Letters, Vol 27, Iss 1, Pp 1-25 (2022)
Abstract Peptididylarginine deiminase type 2 (PADI2) catalyzes the conversion of arginine residues to citrulline residues on proteins. We demonstrate that PADI2 induces T cell activation and investigate how PADI2 promotes activated T cell autonomous
Externí odkaz:
https://doaj.org/article/802dbea7a5d24e36b93b82939b615eb4
Autor:
Xiaoshan Yang, Fuxing Zhou, Pingyun Yuan, Geng Dou, Xuemei Liu, Siying Liu, Xiangdong Wang, Ronghua Jin, Yan Dong, Jun Zhou, Yajie Lv, Zhihong Deng, Shiyu Liu, Xin Chen, Ying Han, Yan Jin
Publikováno v:
Bioactive Materials, Vol 6, Iss 10, Pp 3150-3163 (2021)
Estrogen deficiency is one of the most frequent causes of osteoporosis in postmenopausal women. Under chronic inflammatory conditions caused by estrogen deficiency, activated T cells contribute to elevated levels of proinflammatory cytokines, impaire
Externí odkaz:
https://doaj.org/article/4be6071e69ec4fe8b88113ecb15a3fc6
Autor:
Jian-fei Hu, Zu-wei Wang, Cheng-yu Liao, Zhi-wen Chen, Feng-ping Kang, Cai-feng Lin, Tian-sheng Lin, Long Huang, Yi-feng Tian, Shi Chen
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
BackgroundChimeric antigen receptor-engineered T cell (CAR-T) therapy has shown promising potential for anti-cancer treatment. However, for pancreatic ductal adenocarcinoma (PDAC), the lack of infiltrative ability of these CAR-T cells leads to sub-op
Externí odkaz:
https://doaj.org/article/2148eec4b6ba49a79de5c66018cace8e
Publikováno v:
Jichu yixue yu linchuang, Vol 40, Iss 5, Pp 627-631 (2020)
Objective To study the effect of carboxyamidotriazole (CAI) on CD8+T cells, and to explore the critical mechanism of CAI in reinforcing cytotoxicity of activated T cells. Methods CD8+T cells of mouse were isolated by immunomagnetic beads and divided
Externí odkaz:
https://doaj.org/article/0d7e6f1c065047d7a9ce08102e55f3e1
Publikováno v:
Di-san junyi daxue xuebao, Vol 41, Iss 10, Pp 939-946 (2019)
Objective To investigate the inhibitory effect of G protein-coupled bile acid receptor 1 (TGR5) on endothelin-1 (ET-1)-induced cardiomyocyte hypertrophy and explore the mechanism. Methods Primary cultured neonatal rat cardiomyocytes were exposed to E
Externí odkaz:
https://doaj.org/article/4b8508c4627c4c94a7df68c071c12eec