Zobrazeno 1 - 10
of 69
pro vyhledávání: '"Actin monomer binding"'
Autor:
Miguel Reyes-Múgica, Jessica Sebastian, Vivek S. Peche, Jennifer Baker, Shawn C. West, Sharavana Gurunathan, Brian Feingold, Jeffrey Field, Suneeta Madan-Khetarpal, Hoda Z. Abdel-Hamid
Publikováno v:
American Journal of Medical Genetics Part A. 188:970-977
Nemaline Myopathy (NM) is a disorder of skeletal muscles caused by mutations in sarcomere proteins and characterized by accumulation of microscopic rod or thread-like structures (nemaline bodies) in skeletal muscles. Patients diagnosed with both NM a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::850eaac92522743264ae729fd29c00a1
https://doi.org/10.1002/ajmg.a.62590
https://doi.org/10.1002/ajmg.a.62590
Autor:
I. I. Smaczynska-de Rooij, Ellen G. Allwood, J. S. Palmer, Kathryn R. Ayscough, Joe J. Tyler, L. Abugharsa, L. P. Hancock
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-11 (2021)
Scientific Reports
Scientific Reports
Actin nucleation is the key rate limiting step in the process of actin polymerization, and tight regulation of this process is critical to ensure actin filaments form only at specific times and at defined regions of the cell. WH2 domains are short se
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b3efb6b9a58ff8508bf9e80c6fd9a41b
https://doaj.org/article/da0e863e541247d19898cda32b0978d0
https://doaj.org/article/da0e863e541247d19898cda32b0978d0
Profilin’s affinity for formin regulates the availability of filament ends for actin monomer binding
Autor:
Naomi Courtemanche, Mark E. Zweifel
Publikováno v:
J Mol Biol
Nucleation-promoting proteins tightly regulate actin polymerization in cells. Whereas many of these proteins bind actin monomers directly, formins use the actin-binding protein profilin to dynamically load actin monomers onto their flexible Formin Ho
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aeafb0377fd8be19f35e590b320fe022
https://europepmc.org/articles/PMC7738411/
https://europepmc.org/articles/PMC7738411/
Publikováno v:
Medical Science Monitor : International Medical Journal of Experimental and Clinical Research
BACKGROUND The human LMO2 gene was first cloned from an acute T lymphocytic leukemia patient; it is primarily expressed in hematopoietic and vascular endothelial systems, and functions as a pivotal transcriptional regulator during embryonic hematopoi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7a24b81955697de44b7f44d035cc34a3
https://doi.org/10.12659/msm.903261
https://doi.org/10.12659/msm.903261
Autor:
Mirko Scheibinger, Ying Zhu, Daniel C. Ellwanger, Stefan Heller, Jocelyn F. Krey, Ryan T. Kelly, Dongseok Choi, Peter G. Barr-Gillespie
Hearing and balance rely on small sensory hair cells that reside in the inner ear. To explore dynamic changes in the abundant proteins present in differentiating hair cells, we used nanoliter-scale shotgun mass spectrometry of single cells, each ∼1
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::40f56a7991f9be23ec14a331285c9d4c
Autor:
Katharina A. Quadt, Hirdesh Kumar, Rebecca C. Wade, Saligram Prabhakar Bhargav, Catherine A Moreau, Léanne Strauss, Joachim P. Spatz, Henni Piirainen, Inari Kursula, Jessica Kehrer, Friedrich Frischknecht, Martin Streichfuss
Publikováno v:
PLoS Pathogens
PLoS pathogens 13(5), e1006412-(2017). doi:10.1371/journal.ppat.1006412
PLoS Pathogens, Vol 13, Iss 5, p e1006412 (2017)
PLoS pathogens 13(5), e1006412-(2017). doi:10.1371/journal.ppat.1006412
PLoS Pathogens, Vol 13, Iss 5, p e1006412 (2017)
Profilin is an actin monomer binding protein that provides ATP-actin for incorporation into actin filaments. In contrast to higher eukaryotic cells with their large filamentous actin structures, apicomplexan parasites typically contain only short and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7f0d6904275840844aa9fc09de9fe982
https://www.ncbi.nlm.nih.gov/pubmed/28552953
https://www.ncbi.nlm.nih.gov/pubmed/28552953
Autor:
Antonia Kolokythas, Yalu Zhou, Joel L. Schwartz, Robert J. Cabay, Thomas N. O'Callaghan, Guy R. Adami
Publikováno v:
Journal of oral pathologymedicine : official publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology. 46(7)
Background The genes for PFN1 and TMSB4 are both highly expressed in oral tissue and both encode actin monomer binding proteins thought to play a role in cell motility and possibly other crucial parts of tumor progression. Methods Oral brush cytology
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::74b9dbe62b96fd0c8cfd3a322b3b8549
https://pubmed.ncbi.nlm.nih.gov/27862305
https://pubmed.ncbi.nlm.nih.gov/27862305
Autor:
Paul R. Riley
From the first description of its origins by the Polish-German anatomist Robert Remak in 1855, through to latter day studies into its role in establishing the coronary vasculature (reviewed in1), the embryological epicardium (outermost mesothelial ep
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::476748ee88dbada8b4dfed52bb82e800
https://ora.ox.ac.uk/objects/uuid:945a3999-f921-4935-9078-faecb029157d
https://ora.ox.ac.uk/objects/uuid:945a3999-f921-4935-9078-faecb029157d
Autor:
Tian Li Wang, Michelle M. Thiaville, Denis Wirtz, Ie Ming Shih, Natini Jinawath, Kai Lee Yap, Stephanie I. Fraley, Kentaro Nakayama, Jian-Long Wang
Publikováno v:
Cancer Research. 72:4085-4096
NAC1 is a transcriptional corepressor protein that is essential to sustain cancer cell proliferation and migration. However, the underlying molecular mechanisms of NAC1 function in cancer cells remain unknown. In this study, we show that NAC1 functio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::adb1112f7eb1cc15e8209222f99f38fe
https://doi.org/10.1158/0008-5472.can-12-0302
https://doi.org/10.1158/0008-5472.can-12-0302
Autor:
Zining Wang, Armel Salmon, Guanjing Hu, Lex E. Flagel, Ying Bao, Magdalena Bezanilla, Andrew H. Paterson, Jonathan F. Wendel
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America
Proceedings of the National Academy of Sciences of the United States of America, National Academy of Sciences, 2011, 108 (52), pp.21152-21157. ⟨10.1073/pnas.1115926109⟩
Proceedings of the National Academy of Sciences of the United States of America, 2011, 108 (52), pp.21152-21157. ⟨10.1073/pnas.1115926109⟩
Proceedings of the National Academy of Sciences of the United States of America, National Academy of Sciences, 2011, 108 (52), pp.21152-21157. ⟨10.1073/pnas.1115926109⟩
Proceedings of the National Academy of Sciences of the United States of America, 2011, 108 (52), pp.21152-21157. ⟨10.1073/pnas.1115926109⟩
Cotton is remarkable among our major crops in that four species were independently domesticated, two allopolyploids and two diploids. In each case thousands of years of human selection transformed sparsely flowering, perennial shrubs into highly prod
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6e07ac8a8f9fc2fa5e182599d1a148a0
https://doi.org/10.1073/pnas.1115926109
https://doi.org/10.1073/pnas.1115926109