Zobrazeno 1 - 10
of 37
pro vyhledávání: '"Actin filament branching"'
Publikováno v:
Essays in biochemistry. 63(5)
The complexity of biological systems creates challenges for fully understanding their behaviour. This is particularly true for cell migration which requires the co-ordinated activity of hundreds of individual components within cells. Mathematical mod
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0a1aa565ddffd16b321744856e72d2a6
https://pubmed.ncbi.nlm.nih.gov/31654055
https://pubmed.ncbi.nlm.nih.gov/31654055
Autor:
Graça Raposo, Thierry Dubois, Sophie Vacher, Ivan Bièche, Sonia Agüera-Gonzalez, Laetitia Fuhrmann, Maryse Romao, Anne Vincent-Salomon, Carole El Kesrouani, Marie Irondelle, Alan Guichard, Alessia Castagnino, Catalina Lodillinsky, James E. Bear, Anna Zagryazhskaya-Masson, Christoph S. Clemen, Philippe Chavrier, Antonio Castro-Castro, Angelika A. Noegel
Publikováno v:
Oncogene
Oncogene, Nature Publishing Group, 2018, 37 (50), pp.6425-6441. ⟨10.1038/s41388-018-0422-x⟩
Oncogene, Nature Publishing Group, 2018, 37 (50), pp.6425-6441. ⟨10.1038/s41388-018-0422-x⟩
Membrane type 1-matrix metalloproteinase (MT1-MMP), a membrane-tethered protease, is key for matrix breakdown during cancer invasion and metastasis. Assembly of branched actin networks by the Arp2/3 complex is required for MT1-MMP traffic and formati
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::46a2e597e89fcb1faa488d31fac8171a
https://hal.archives-ouvertes.fr/hal-02377262/document
https://hal.archives-ouvertes.fr/hal-02377262/document
Autor:
Michaela Schweizer, Lars Fester, Stefan Kindler, Sabine Windhorst, Gabriele M. Rune, Nicola Brandt, Jan-Dietrich Köster, Birthe Leggewie, Christine Blechner
Publikováno v:
Cellular Signalling. 28:83-90
Long-lasting synaptic plasticity is often accompanied by morphological changes as well as formation and/or loss of dendritic spines. Since the spine cytoskeleton mainly consists of actin filaments, morphological changes are primarily controlled by ac
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::daf5db6a598feb1ddd23b916a46d4abf
https://doi.org/10.1016/j.cellsig.2015.10.016
https://doi.org/10.1016/j.cellsig.2015.10.016
Publikováno v:
Current Biology-CB
Current Biology-CB, Elsevier, 2018, 28 (16), pp.2647-2656.e4. ⟨10.1016/j.cub.2018.06.028⟩
Current Biology-CB, 2018, 28 (16), pp.2647-2656.e4. ⟨10.1016/j.cub.2018.06.028⟩
Current Biology-CB, Elsevier, 2018, 28 (16), pp.2647-2656.e4. ⟨10.1016/j.cub.2018.06.028⟩
Current Biology-CB, 2018, 28 (16), pp.2647-2656.e4. ⟨10.1016/j.cub.2018.06.028⟩
Summary Coordination between actin filaments and microtubules is critical to complete important steps during cell division. For instance, cytoplasmic actin filament dynamics play an active role in the off-center positioning of the spindle during meta
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9e077080a26efb852448247079b15132
https://hal.archives-ouvertes.fr/hal-02333513
https://hal.archives-ouvertes.fr/hal-02333513
Autor:
Peter A. Thomason, Theresia E. B. Stradal, Thomas Klünemann, Frieda Kage, Shashi Prakash Singh, Wulf Blankenfeldt, Robert H. Insall, Matthias Schaks, Klemens Rottner, Anika Steffen
Publikováno v:
SSRN Electronic Journal.
Cell migration often involves the formation of sheet‐like lamellipodia, generated by actin filament branching through Arp2/3 complex. In these structures, the latter is activated by WAVE regulatory complex (WRC) downstream of small GTPases of the R
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::56a75fa498f4f576febc042b118bfe63
https://doi.org/10.2139/ssrn.3188452
https://doi.org/10.2139/ssrn.3188452
Autor:
Robert A. Campbell, Robert H. Lee, James E. Bear, Dorsaf Ghalloussi, Andrew S. Weyrich, Raymond Piatt, Jeremy D. Rotty, Swetha Pasala, Brian C. Cooley, Congying Wu, Kathryn O. Poe, David S. Paul, Wolfgang Bergmeier, Kellie R. Machlus, Joseph E. Italiano, Caterina Casari
Publikováno v:
Blood advances. 1(18)
Actin reorganization regulates key processes in platelet activation. Here we examined the role of the Arp2/3 complex, an essential component in actin filament branching, in platelet function. The Arpc2 gene, encoding the p34 subunit of the Arp2/3 com
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e77b564e4e78152a57883208b752eac9
https://pubmed.ncbi.nlm.nih.gov/29104956
https://pubmed.ncbi.nlm.nih.gov/29104956
The Sharpin interactome reveals a role for Sharpin in lamellipodium formation via the Arp2/3 complex
Autor:
Martin J. Humphries, Siiri I. Salomaa, Meraj Hasan Khan, Elena Kremneva, Umar Butt, Guillaume Jacquemet, Mitro Miihkinen, Jeroen Pouwels, Takahiro Deguchi, Pekka Lappalainen
Publikováno v:
Journal of Cell Science. 130(18)
Sharpin, a multifunctional adaptor protein, regulates several signalling pathways. For example, Sharpin enhances signal-induced NF-κB signalling as part of the linear ubiquitin assembly complex (LUBAC) and inhibits integrins, the T cell receptor, ca
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5919c77b546748f9cb14f7b18c40e395
https://doi.org/10.1242/jcs.200329
https://doi.org/10.1242/jcs.200329
Autor:
Andre J. Van Wijnen, Amel Dudakovic, Rebekah M. Samsonraj, Cody McGrath, Janet Rubin, Buer Sen, Zhihui Xie, Maya Styner, Gunes Uzer
Publikováno v:
Stem cells (Dayton, Ohio). 35(6)
Actin structure contributes to physiologic events within the nucleus to control mesenchymal stromal cell (MSC) differentiation. Continuous cytochalasin D (Cyto D) disruption of the MSC actin cytoskeleton leads to osteogenic or adipogenic differentiat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::334177c9678931b00fcc8a85c72d7087
https://pubmed.ncbi.nlm.nih.gov/28371128
https://pubmed.ncbi.nlm.nih.gov/28371128
Publikováno v:
eNeuro
The actin cytoskeleton is involved in key neuronal functions such as synaptic transmission and morphogenesis. However, the roles and regulation of actin cytoskeleton in memory formation remain to be clarified. In this study, we unveil the mechanism w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cbbfa8d77f746e1899392d10b6e0b42b
http://europepmc.org/articles/PMC5126706
http://europepmc.org/articles/PMC5126706
Autor:
Manuel Théry, Jean-Louis Martiel, François Nédélec, Wenxiang Cao, Christophe Guérin, Enrique M. De La Cruz, Hajer Ennomani, Gaëlle Letort, Laurent Blanchoin
Publikováno v:
Current Biology-CB
Current Biology-CB, Elsevier, 2016, 26 (5), pp.616-626
Current Biology-CB, 2016, 26 (5), pp.616-626. ⟨10.1016/j.cub.2015.12.069⟩
Current Biology-CB, Elsevier, 2016, 26 (5), pp.616-626. ⟨10.1016/j.cub.2015.12.069⟩
Current Biology-CB, Elsevier, 2016, 26 (5), pp.616-626
Current Biology-CB, 2016, 26 (5), pp.616-626. ⟨10.1016/j.cub.2015.12.069⟩
Current Biology-CB, Elsevier, 2016, 26 (5), pp.616-626. ⟨10.1016/j.cub.2015.12.069⟩
International audience; Actomyosin contractility plays a central role in a wide range of cellular processes, including the establishment of cell polarity, cell migration, tissue integrity, and morphogenesis during development. The contractile respons
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0fda42746ef228f16bde74edeb3460e0
https://hal.archives-ouvertes.fr/hal-01281708
https://hal.archives-ouvertes.fr/hal-01281708