Zobrazeno 1 - 10
of 797
pro vyhledávání: '"AcrAB"'
Publikováno v:
Iraqi Journal of Industrial Research, Vol 11, Iss 1, Pp 67-75 (2024)
Enterobacteriaceae are Gram-negative bacteria that have many mechanisms to survive in contaminated environments. Klebsiella pneumoniae is one of them that express efflux pump genes in the presence of heavy metals, like AcrAb and OqxA genes. The purpo
Externí odkaz:
https://doaj.org/article/1c2ec9312a024f338c82e33a8d7283e2
Publikováno v:
Virulence, Vol 15, Iss 1 (2024)
Salmonella enterica serovar Typhi (S. Typhi) causes typhoid fever, a systemic infection that affects millions of people worldwide. S. Typhi can invade and survive within host cells, such as intestinal epithelial cells and macrophages, by modulating t
Externí odkaz:
https://doaj.org/article/7150bf028b034ababce1151df82f5df4
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 14 (2024)
ObjectiveThe emergence of clinical Klebsiella pneumoniae strains harboring acrAB-tolC genes in the chromosome, along with the presence of two repetitive tandem core structures for blaKPC-2 and blaCTX-M-65 genes on a plasmid, has presented a significa
Externí odkaz:
https://doaj.org/article/8185b44bad794e519df4c4472074bc83
Akademický článek
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Autor:
Rawaf Alenazy
Publikováno v:
Journal of King Saud University: Science, Vol 36, Iss 4, Pp 103116- (2024)
The infections of multidrug-resistant bacteria, particularly the infections caused by Gram-negative bacterial infections, are considered the main global serious health problems. Multidrug-resistant bacteria possess different resistance mechanisms, th
Externí odkaz:
https://doaj.org/article/8811efaf589a4aa68dc6bce58553c872
Publikováno v:
Frontiers in Drug Discovery, Vol 4 (2024)
Antimicrobial resistance poses an urgent and formidable global public health threat. The escalation of bacterial multidrug resistance to antibiotics has the potential to become a leading cause of global mortality if there is no substantial improvemen
Externí odkaz:
https://doaj.org/article/98b89259e6634792861fe0e8f1549b49
Autor:
Pavel A. Nazarov, Vladislav S. Maximov, Alexander M. Firsov, Marina V. Karakozova, Veronika Panfilova, Elena A. Kotova, Maxim V. Skulachev, Yuri N. Antonenko
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 11, p 6137 (2024)
Mitochondria-targeted antioxidants (MTAs) have been studied quite intensively in recent years as potential therapeutic agents and vectors for the delivery of other active substances to mitochondria and bacteria. Their most studied representatives are
Externí odkaz:
https://doaj.org/article/60d327de2eb64c31baf99c99657766e1
Autor:
Samual C. Allgood, Chih-Chia Su, Amy L. Crooks, Christian T. Meyer, Bojun Zhou, Meredith D. Betterton, Michael R. Barbachyn, Edward W. Yu, Corrella S. Detweiler
Publikováno v:
mBio, Vol 14, Iss 6 (2023)
ABSTRACTNew approaches for combating microbial infections are needed. One strategy for disrupting pathogenesis involves developing compounds that interfere with bacterial virulence. A critical molecular determinant of virulence for Gram-negative bact
Externí odkaz:
https://doaj.org/article/c39352faf2c44a41aedbedba1f9e7998
Publikováno v:
Medicine in Drug Discovery, Vol 20, Iss , Pp 100164- (2023)
Multidrug resistance (MDR) poses a severe threat to human health. The existence of efflux pumps primarily contributes to resistance in Gram-negative bacterial infections. Efflux pump inhibitors (EPIs) can potentially improve the efficacy of antibioti
Externí odkaz:
https://doaj.org/article/24ed83f1e1454130a238b95b3610546d
Publikováno v:
mSphere, Vol 8, Iss 5 (2023)
ABSTRACT Efflux and motility are two key biological functions in bacteria. Recent findings have shown that efflux impacts flagellum biosynthesis and motility in Escherichia coli and other bacteria. AcrR is known to be the major transcriptional repres
Externí odkaz:
https://doaj.org/article/8bb8d9a1e304444e8fb2771e1c875fd8