Výsledky vyhledávání - "Ackerman, Eduardo Jacobo Miranda"

Additional file 1 of A metabolic switch regulates the transition between growth and diapause in C. elegans

Autor: Sider Penkov, Bharath Kumar Raghuraman, Erkut, Cihan, Oertel, Jana, Galli, Roberta, Ackerman, Eduardo Jacobo Miranda, Vorkel, Daniela, Jean-Marc Verbavatz, Koch, Edmund, Fahmy, Karim, Shevchenko, Andrej, Teymuras V. Kurzchalia

Additional file 1: Figure S1. Heat flow of C. elegans undergoing reproductive growth or developmental arrest. Left panels - biological replicates generated in various experiments. Right panels - corresponding median heat flow per experiment. Curves r

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Additional file 5 of A metabolic switch regulates the transition between growth and diapause in C. elegans

Additional file 5: Figure S5. AAK-2 does not affect exit from dauer state but is required for the preservation of energy reserves in dauers and the gluconeogenic mode in adults. a Scheme of the SDS treatment experiment. b Survival after SDS treatment

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Additional file 6 of A metabolic switch regulates the transition between growth and diapause in C. elegans

Additional file 6: Figure S6. LC-MS/MS (MS Western) analysis of metabolic enzymes. a-f Multiple peptide-based concordant quantification of an example protein isocitrate lyase (ICL-1). Extracted ion chromatograms (XIC) of ICL-1 endogenous peptides (a)

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Additional file 3 of A metabolic switch regulates the transition between growth and diapause in C. elegans

Additional file 3: Figure S3. Cumulative heat dissipation of larvae in a developmentally arrested state. Left panels - biological replicates generated in various experiments. Right panels - corresponding median heat per experiment. a Heat produced by

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Additional file 2 of A metabolic switch regulates the transition between growth and diapause in C. elegans

Additional file 2: Figure S2. Electron micrographs of a daf-2 arrested L3 larva grown at 25 °C in the presence of DA. The body is not radially constricted but multiple lipid droplets are visible (left panel, arrowheads). Alae are absent (left panel)

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Additional file 4 of A metabolic switch regulates the transition between growth and diapause in C. elegans

Additional file 4: Figure S4. DAF-16 controls the catabolism of energy reserves in dauer larvae. a TLC of lipids and sugars in daf-2 dauers and daf-2;daf-12 arrested L3 larvae grown at 25 °C, and wild-type (N2) dauers and daf-16 dauer-like larvae gr

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Additional file 7 of A metabolic switch regulates the transition between growth and diapause in C. elegans

Additional file 7: Figure S7. Control of the TCA and glyoxylate cycle. Absolute quantification of enzymes of the TCA cycle and the glyoxylate shunt in daf-2 and daf-2;aak-2 grown at 25 °C with or without DA compared to daf-2 animals at 15 °C. The r

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