Výsledky vyhledávání - "Acidic amino acids"

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Akademický článek

N-Succinylaspartic-Acid-Conjugated Riluzole Is a Safe and Potent Colon-Targeted Prodrug of Riluzole against DNBS-Induced Rat Colitis

Autor: Jaejeong Kim, Changyu Kang, Jin-Wook Yoo, In-Soo Yoon, Yunjin Jung

Publikováno v: Pharmaceutics, Vol 15, Iss 11, p 2638 (2023)

In our previous study, riluzole azo-linked to salicylic acid (RAS) was prepared as a colon-targeted prodrug of riluzole (RLZ) to facilitate the repositioning of RLZ as an anticolitic drug. RAS is more effective against rat colitis than RLZ and sulfas

Externí odkaz: https://doaj.org/article/9ea6f3d0f61a46de8c9dd9642f64ae1b

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Akademický článek

Utilization of L-glutamate as a preferred or sole nutrient in Pseudomonas aeruginosa PAO1 depends on genes encoding for the enhancer-binding protein AauR, the sigma factor RpoN and the transporter complex AatJQMP

Autor: Benjamin R. Lundgren, Joseph M. Shoytush, Ryan A. Scheel, Safreen Sain, Zaara Sarwar, Christopher T. Nomura

Publikováno v: BMC Microbiology, Vol 21, Iss 1, Pp 1-20 (2021)

Abstract Background Glutamate and aspartate are preferred nutrients for a variety of microorganisms. In the case for many Pseudomonas spp., utilization of these amino acids is believed to be dependent on a transporter complex comprised of a periplasm

Externí odkaz: https://doaj.org/article/85d6afe3166a4386a14ba3f2049b6221

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