Regional Distributions of Iron, Copper and Zinc and Their Relationships With Glia in a Normal Aging Mouse Model

Autor: Thomas A. Walker, Maria Suessmilch, Achvini Sriskanthanathan, Christos Michaelides, Azhaar Ashraf, Kalotina Geraki, Antigoni Ekonomou, Po-Wah So, Semhar Abraha, Adam Parkes, Harold G. Parkes

Publikováno v: Frontiers in Aging Neuroscience
Ashraf, A, Michaelides, C, Walker, T A, Ekonomou, A, Suessmilch, M, Sriskanthanathan, A, Abraha, S, Parkes, A, Parkes, H G, Geraki, K & So, P-W 2019, ' Regional distributions of iron, copper and zinc and their relationships with glia in a normal aging mouse model ', Frontiers in aging neuroscience, vol. 11, 351 . https://doi.org/10.3389/fnagi.2019.00351
Frontiers in Aging Neuroscience, Vol 11 (2019)

Microglia and astrocytes can quench metal toxicity to maintain tissue homeostasis, but with age, increasing glial dystrophy alongside metal dyshomeostasis may predispose the aged brain to acquire neurodegenerative diseases. The aim of the present stu

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::110579cd7fe91a0d637804838e221a68
https://pubmed.ncbi.nlm.nih.gov/31920630