Zobrazeno 1 - 10
of 167
pro vyhledávání: '"Achkar JP"'
Autor:
Momozawa, Y, Dmitrieva, J, Theatre, E, Deffontaine, V, Rahmouni, S, Charloteaux, B, Crins, F, Docampo, E, Elansary, M, Gori, AS, Lecut, C, Mariman, R, Mni, M, Oury, C, Altukhov, I, Alexeev, D, Aulchenko, Y, Amininejad, L, Bouma, G, Hoentjen, F, Lowenberg, M, Oldenburg, B, Pierik, MJ, de Jong, AE, van der Woude, C.J., Visschedijk, MC, Lathrop, M, Hugot, JP, Weersma, RK, Vos, M, Franchimont, D, Vermeire, S, Kubo, M, Louis, E, Georges, M, Abraham, C, Achkar, JP, Ahmad, T, Ananthakrishnan, AN, Andersen, V, Anderson, CA, Andrews, JM, Annese, V, Aumais, G, Baidoo, L, Baldassano, RN, Bampton, PA, Barclay, M, Barrett, JC, Bayless, TM, Bethge, J, Bitton, A, Boucher, G, Brand, S, Brandt, B, Brant, SR, Buning, C, Chew, A, Cho, JH, Cleynen, I, Cohain, A, Croft, A, Daly, MJ, D'Amato, M, Danese, S, Jong, D, Denapiene, G, Denson, LA, Devaney, KL, Dewit, O, D'Inca, R, Dubinsky, M, Duerr, RH, Edwards, C, Ellinghaus, D, Essers, J, Ferguson, LR, Festen, EA, Fleshner, P, Florin, T, Franke, A, Fransen, K, Gearry, R, Gieger, C, Glas, J, Goyette, P, Green, T, Griffiths, AM, Guthery, SL, Hakonarson, H, Halfvarson, J, Hanigan, K, Haritunians, T, de Hart, A, Hawkey, C, Hayward, NK, Hedl, M, Henderson, P, Hu, XH, Huang, HL, Hui, KY, Imielinski, M, Ippoliti, A, Jonaitis, L, Jostins, L, Karlsen, TH, Kennedy, NA, Khan, MA, Kiudelis, G, Krishnaprasad, K, Kugathasan, S, Kupcinskas, L, Latiano, A, Laukens, D, Lawrance, IC, Lee, JC, Lees, CW, Leja, M, van Limbergen, J, Lionetti, P, Liu, JZ, Mahy, G, Mansfield, J, Massey, D, Mathew, CG, McGovern, DPB, Milgrom, R, Mitrovic, M, Montgomery, GW, Mowat, C, Newman, W, Ng, A, Ng, SC, Ng, SME, Nikolaus, S, Ning, K, Nothen, M, Oikonomou, I, Palmieri, O, Parkes, M, Phillips, A, Ponsioen, CY, Potocnik, U, Prescott, NJ, Proctor, DD, Radford-Smith, G, Rahier, JF, Raychaudhuri, S, Regueiro, M, Rieder, F, Rioux, JD, Ripke, S, Roberts, R, Russell, RK, Sanderson, JD, Sans, M, Satsangi, J, Schadt, EE, Schreiber, S, Schulte, D, Schumm, LP, Scott, R, Seielstad, M, Sharma, Y, Silverberg, MS, Simms, LA, Skieceviciene, J, Spain, SL, Steinhart, AH, Stempak, JM, Stronati, L, Sventoraityte, J, Targan, SR, Taylor, KM, Velde, A, Torkvist, L, Tremelling, M, van Sommeren, S, Vasiliauskas, E, Verspaget, HW, Walters, T, Wang, K, Wang, MH, Wei, Z, Whiteman, D, Wijmenga, C, Wilson, DC, Winkelmann, J, Xavier, RJ, Zhang, B, Zhang, CK, Zhang, H, Zhang, W, Zhao, HY, Zhao, ZZ
Publikováno v:
NATURE COMMUNICATIONS
Momozawa, Y, Dmitrieva, J, Théâtre, E, Deffontaine, V, Rahmouni, S, Charloteaux, B, Crins, F, Docampo, E, Elansary, M, Gori, A-S, Lecut, C, Mariman, R, Mni, M, Oury, C, Altukhov, I, Alexeev, D, Aulchenko, Y, Amininejad, L, Bouma, G, Hoentjen, F, Löwenberg, M, Oldenburg, B, Pierik, M J, Vander Meulen-de Jong, A E, Janneke van der Woude, C, Visschedijk, M C, Lathrop, M, Hugot, J-P, Weersma, R K, De Vos, M, Franchimont, D, Vermeire, S, Kubo, M & Louis, E & Georges, M 2018, ' IBD risk loci are enriched in multigenic regulatory modules encompassing putative causative genes ', Nature Communications, vol. 9, no. 1, pp. 2427 . https://doi.org/10.1038/s41467-018-04365-8
Nature Communications
Nature Communications, 9:2427. Nature Publishing Group
Nature communications, Vol. 9, no. 1, p. 2427 (2018)
Momozawa, Y, Dmitrieva, J, Théâtre, E, Deffontaine, V, Rahmouni, S, Charloteaux, B, Crins, F, Docampo, E, Elansary, M, Gori, A-S, Lecut, C, Mariman, R, Mni, M, Oury, C, Altukhov, I, Alexeev, D, Aulchenko, Y, Amininejad, L, Bouma, G, Hoentjen, F, Löwenberg, M, Oldenburg, B, Pierik, M J, Vander Meulen-de Jong, A E, Janneke van der Woude, C, Visschedijk, M C, Lathrop, M, Hugot, J-P, Weersma, R K, De Vos, M, Franchimont, D, Vermeire, S, Kubo, M & Louis, E & Georges, M 2018, ' IBD risk loci are enriched in multigenic regulatory modules encompassing putative causative genes ', Nature Communications, vol. 9, no. 1, pp. 2427 . https://doi.org/10.1038/s41467-018-04365-8
Nature Communications
Nature Communications, 9:2427. Nature Publishing Group
Nature communications, Vol. 9, no. 1, p. 2427 (2018)
GWAS have identified >200 risk loci for Inflammatory Bowel Disease (IBD). The majority of disease associations are known to be driven by regulatory variants. To identify the putative causative genes that are perturbed by these variants, we generate a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::0dfdfd477db43cfdeff0fe3f26a98b51
https://biblio.ugent.be/publication/8582997/file/8582999
https://biblio.ugent.be/publication/8582997/file/8582999
Autor:
Ombrello MJ, Arthur VL, Remmers EF, Hinks A, Tachmazidou I, Grom AA, Foell D, Martini A, Gattorno M, Özen S, Prahalad S, Zeft AS, Bohnsack JF, Ilowite NT, Mellins ED, Russo R, Len C, Hilario MO, Oliveira S, Yeung RS, Rosenberg AM, Wedderburn LR, Anton-Lopez J, Haas JP, Rosen-Wolff A, Minden K, Tenbrock K, Demirkaya E, Cobb J, Baskin E, Signa S, Shuldiner E, Duerr RH, Achkar JP, Kamboh MI, Kaufman KM, Kottyan LC, Pinto D, Scherer SW, Alarcón-Riquelme ME, Docampo E, Estivill X, Gül A, British Society of Pediatric and Adolescent Rheumatology (BSPAR) Study Group, In, Langefeld CD, Thompson S, Zeggini E, Kastner DL, Woo P, Thomson W
Publikováno v:
ANNALS OF THE RHEUMATIC DISEASES
r-FSJD. Repositorio Institucional de Producción Científica de la Fundació Sant Joan de Déu
instname
r-FSJD: Repositorio Institucional de Producción Científica de la Fundació Sant Joan de Déu
Fundació Sant Joan de Déu
r-FSJD. Repositorio Institucional de Producción Científica de la Fundació Sant Joan de Déu
instname
r-FSJD: Repositorio Institucional de Producción Científica de la Fundació Sant Joan de Déu
Fundació Sant Joan de Déu
OBJECTIVES: Juvenile idiopathic arthritis (JIA) is a heterogeneous group of conditions unified by the presence of chronic childhood arthritis without an identifiable cause. Systemic JIA (sJIA) is a rare form of JIA characterised by systemic inflammat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::56d3a0183cca8073cfa29f04865a06ae
http://fundanet.fsjd.org/Publicaciones/ProdCientif/PublicacionFrw.aspx?id=10524
http://fundanet.fsjd.org/Publicaciones/ProdCientif/PublicacionFrw.aspx?id=10524
Autor:
Rivas, Manuel A, Graham, Daniel, Sulem, Patrick, Stevens, Christine, Desch, A Nicole, Goyette, Philippe, Gudbjartsson, Daniel, Jonsdottir, Ingileif, Thorsteinsdottir, Unnur, Degenhardt, Frauke, Mucha, Sören, Kurki, Mitja I, Li, Dalin, D'Amato, Mauro, Annese, Vito, Vermeire, Severine, Weersma, Rinse K, Halfvarson, Jonas, Paavola-Sakki, Paulina, Lappalainen, Maarit, Lek, Monkol, Cummings, Beryl, Tukiainen, Taru, Haritunians, Talin, Halme, Leena, Koskinen, Lotta LE, Ananthakrishnan, Ashwin N, Luo, Yang, Heap, Graham A, Visschedijk, Marijn C, UK IBD Genetics Consortium, NIDDK IBD Genetics Consortium, MacArthur, Daniel G, Neale, Benjamin M, Ahmad, Tariq, Anderson, Carl A, Brant, Steven R, Duerr, Richard H, Silverberg, Mark S, Cho, Judy H, Palotie, Aarno, Saavalainen, Päivi, Kontula, Kimmo, Färkkilä, Martti, McGovern, Dermot PB, Franke, Andre, Stefansson, Kari, Rioux, John D, Xavier, Ramnik J, Daly, Mark J, Barrett, J, De Lane, K, Edwards, C, Hart, A, Hawkey, C, Jostins, L, Kennedy, N, Lamb, C, Lee, J, Lees, C, Mansfield, J, Mathew, C, Mowatt, C, Newman, B, Nimmo, E, Parkes, M, Pollard, M, Prescott, N, Randall, J, Rice, D, Satsangi, J, Simmons, A, Tremelling, M, Uhlig, H, Wilson, D, Abraham, C, Achkar, JP, Bitton, A, Boucher, G, Croitoru, K, Fleshner, P, Glas, J, Kugathasan, S, Limbergen, JV, Milgrom, R, Proctor, D, Regueiro, M, Schumm, PL, Sharma, Y, Stempak, JM, Targan, Wang, MH
Protein-truncating variants protective against human disease provide in vivo validation of therapeutic targets. Here we used targeted sequencing to conduct a search for protein-truncating variants conferring protection against inflammatory bowel dise
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eaadf8395c16d8328f3ee4203f7981ea
https://www.repository.cam.ac.uk/handle/1810/282972
https://www.repository.cam.ac.uk/handle/1810/282972
Autor:
Cleynen, Isabelle, Boucher, Gabrielle, Jostins, Luke, Schumm, L. Philip, Zeissig, Sebastian, Ahmad, Tariq, Andersen, Vibeke, Andrews, Jane M., Annese, Vito, Brand, Stephan, Brant, Steven R., Cho, Judy H., Daly, Mark J., Dubinsky, Marla, Duerr, Richard H., Ferguson, Lynnette R., Franke, Andre, Gearry, Richard B., Goyette, Philippe, Hakonarson, Hakon, Halfvarson, Jonas, Hov, Johannes R., Huang, Hailang, Kennedy, Nicholas A., Kupcinskas, Limas, Lawrance, Ian C., Lee, James C., Satsangi, Jack, Schreiber, Stephan, Théâtre, Emilie, Van Der Meulen De Jong, Andrea E, Weersma, Rinse K., Wilson, David C., Parkes, Miles, Vermeire, Severine, Rioux, John D., Mansfield, John, Silverberg, Mark S., Radford Smith, Graham, Mcgovern, Dermot P. B., Barrett, Jeffrey C., Lees, Charlie W, Abraham, C, Achkar, Jp, Ahmad, T, Amininejad, L, Ananthakrishnan, An, Andersen, V, Anderson, Ca, Andrews, Jm, Annese, V, Aumais, G, Baidoo, L, Baldassano, Rn, Bampton, Pa, Barclay, M, Barrett, Jc, Bayless, Tm, Bethge, J, Bis, Jc, Bitton, A, Boucher, G, Brand, S, Brandt, B, Brant, Sr, Büning, C, Chew, A, Cho, Jh, Cleynen, I, Cohain, A, Croft, A, Daly, Mj, D'Amato, M, Danese, S, De Jong, D, De Vos, M, Denapiene, G, Denson, La, Devaney, K, Dewit, O, D'Inca, R, Dubinsky, M, Duerr, Rh, Edwards, C, Ellinghaus, D, Essers, J, Ferguson, Lr, Festen, Ea, Fleshner, P, Florin, T, Franchimont, D, Franke, A, Fransen, K, Gearry, R, Georges, M, Gieger, C, Glas, J, Goyette, P, Green, T, Griffiths, Am, Guthery, Sl, Hakonarson, H, Halfvarson, J, Hanigan, K, Haritunians, T, Hart, A, Hawkey, C, Hayward, Nk, Hedl, M, Henderson, P, Hu, X, Huang, H, Hui, Ky, Imielinski, M, Ippoliti, A, Jonaitis, L, Jostins, L, Karlsen, Th, Kennedy, Na, Khan, Ma, Kiudelis, G, Krishnaprasad, K, Kugathasan, S, Kupcinskas, L, Latiano, A, Laukens, D, Lawrance, Ic, Lee, Jc, Lees, Cw, Leja, M, Van Limbergen, J, Lionetti, P, Liu, Jz, Louis, E, Mahy, G, Mansfield, J, Massey, D, Mathew, Cg, Mcgovern, Dp, Milgrom, R, Mitrovic, M, Montgomery, Gw, Mowat, C, Newman, W, Ng, A, Ng, Sc, Ng, Sm, Nikolaus, S, Ning, K, Nöthen, M, Oikonomou, I, Palmieri, O, Parkes, M, Phillips, A, Ponsioen, Cy, Potocnik, U, Prescott, Nj, Proctor, Dd, Radford Smith, G, Rahier, Jf, Raychaudhuri, S, Regueiro, M, Rieder, F, Rioux, Jd, Ripke, S, Roberts, R, Russell, Rk, Sanderson, Jd, Sans, M, Satsangi, J, Schadt, Ee, Schreiber, S, Schumm, Lp, Scott, R, Seielstad, M, Sharma, Y, Silverberg, Ms, Simms, La, Skieceviciene, J, Spain, Sl, Steinhart, A, Stempak, Jm, Stronati, Laura, Sventoraityte, J, Targan, Sr, Taylor, Km, ter Velde, A, Theatre, E, Torkvist, L, Tremelling, M, van der Meulen, A, van Sommeren, S, Vasiliauskas, E, Vermeire, S, Verspaget, Hw, Walters, T, Wang, K, Wang, Mh, Weersma, Rk, Wei, Z, Whiteman, D, Wijmenga, C, Wilson, Dc, Winkelmann, J, Xavier, Rj, Zeissig, S, Zhang, B, Zhang, Ck, Zhang, H, Zhang, W, Zhao, H, Zhao, Zz
Publikováno v:
Cleynen, I, Boucher, G, Jostins, L, Schumm, L P, Zeissig, S, Ahmad, T, Andersen, V, Andrews, J M, Annese, V, Brand, S, Brant, S R, Cho, J H, Daly, M J, Dubinsky, M, Duerr, R H, Ferguson, L R, Franke, A, Gearry, R B, Goyette, P, Hakonarson, H, Halfvarson, J, Hov, J R, Huang, H, Kennedy, N A, Kupcinskas, L, Lawrance, I C, Lee, J C, Satsangi, J, Schreiber, S, Théâtre, E, van der Meulen-de Jong, A E, Weersma, R K, Wilson, D C, Parkes, M, Vermeire, S, Rioux, J D, Mansfield, J, Silverberg, M S, Radford-Smith, G, McGovern, D P B, Barrett, J C, Lees, C W & International Inflammatory Bowel Disease Genetics Consortium 2016, ' Inherited determinants of Crohn's disease and ulcerative colitis phenotypes : a genetic association study ', The Lancet, vol. 387, no. 10014, pp. 156-167 . https://doi.org/10.1016/S0140-6736(15)00465-1
LANCET
Lancet, 387(10014), 156-167
Lancet (London, England)
Cleynen, I, Boucher, G, Jostins, L, Schumm, L P, Zeissig, S, Ahmad, T, Andersen, V, Andrews, J M, Annese, V, Brand, S, Brant, S R, Cho, J H, Daly, M J, Dubinsky, M, Duerr, R H, Ferguson, L R, Franke, A, Gearry, R B, Goyette, P, Hakonarson, H, Halfvarson, J, Hov, J R, Huang, H, Kennedy, N A, Kupcinskas, L, Lawrance, I C, Lee, J C, Satsangi, J, Schreiber, S, Théâtre, E, van der Meulen-de Jong, A E, Weersma, R K, Wilson, D C, Parkes, M, Vermeire, S, Rioux, J D, Mansfield, J, Silverberg, M S, Radford-Smith, G, McGovern, D P B & Barrett, J C & Lees, C W 2016, ' Inherited determinants of Crohn's disease and ulcerative colitis phenotypes: a genetic association study ', The Lancet, vol. 387, no. 10014, pp. 156-167 . https://doi.org/10.1016/S0140-6736(15)00465-1
Lancet (London, England), Vol. 387, no. 10014, p. 156-67 (2016)
The Lancet, 387(10014), 156-167. ELSEVIER SCIENCE INC
LANCET
Lancet, 387(10014), 156-167
Lancet (London, England)
Cleynen, I, Boucher, G, Jostins, L, Schumm, L P, Zeissig, S, Ahmad, T, Andersen, V, Andrews, J M, Annese, V, Brand, S, Brant, S R, Cho, J H, Daly, M J, Dubinsky, M, Duerr, R H, Ferguson, L R, Franke, A, Gearry, R B, Goyette, P, Hakonarson, H, Halfvarson, J, Hov, J R, Huang, H, Kennedy, N A, Kupcinskas, L, Lawrance, I C, Lee, J C, Satsangi, J, Schreiber, S, Théâtre, E, van der Meulen-de Jong, A E, Weersma, R K, Wilson, D C, Parkes, M, Vermeire, S, Rioux, J D, Mansfield, J, Silverberg, M S, Radford-Smith, G, McGovern, D P B & Barrett, J C & Lees, C W 2016, ' Inherited determinants of Crohn's disease and ulcerative colitis phenotypes: a genetic association study ', The Lancet, vol. 387, no. 10014, pp. 156-167 . https://doi.org/10.1016/S0140-6736(15)00465-1
Lancet (London, England), Vol. 387, no. 10014, p. 156-67 (2016)
The Lancet, 387(10014), 156-167. ELSEVIER SCIENCE INC
Background: Crohn's disease and ulcerative colitis are the two major forms of inflammatory bowel disease; treatment strategies have historically been determined by this binary categorisation. Genetic studies have identified 163 susceptibility loci fo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::50f04919d18474155a26114385411d1b
https://findresearcher.sdu.dk:8443/ws/files/128924437/Inherited_determinants_of_Crohn_s_disease_and_ulcerative_colitis_phenotypes.pdf
https://findresearcher.sdu.dk:8443/ws/files/128924437/Inherited_determinants_of_Crohn_s_disease_and_ulcerative_colitis_phenotypes.pdf
Autor:
Ombrello MJ, Remmers EF, Tachmazidou I, Grom A, Foell D, Haas JP, Martini A, Gattorno M, Özen S, Prahalad S, Zeft AS, Bohnsack JF, Mellins ED, Ilowite NT, Russo R, Len C, Hilario MO, Oliveira S, Yeung RS, Rosenberg A, Wedderburn LR, Anton-Lopez J, Schwarz T, Hinks A, Bilginer Y, Park J, Cobb J, Satorius CL, Han B, Baskin E, Signa S, Duerr RH, Achkar JP, Kamboh MI, Kaufman KM, Kottyan LC, Pinto D, Scherer SW, Alarcón-Riquelme ME, Docampo E, Estivill X, Gül A, British Society of Pediatric and Adolescent Rheumatology (BSPAR) Study Group, Childhood Arthritis Prospective Study (CAPS) Group, Randomized Placebo Phase Study of Rilonacept in sJIA (RAPPORT) Investigators, Sparks-Childhood Arthritis Response to Medication Study (CHARMS) Group, Biologically Based Outcome Predictors in JIA (BBOP) Group, de Bakker PI, Raychaudhuri S, Langefeld CD, Thompson S, Zeggini E, Thomson W, Kastner DL, Woo P, International Childhood Arthritis Genetics (INCHARGE) Consortium, British Society of Pediatric and Adolescent Rheumatology BSPAR Study Group
Publikováno v:
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
r-FSJD: Repositorio Institucional de Producción Científica de la Fundació Sant Joan de Déu
Fundació Sant Joan de Déu
r-FSJD. Repositorio Institucional de Producción Científica de la Fundació Sant Joan de Déu
instname
r-FSJD: Repositorio Institucional de Producción Científica de la Fundació Sant Joan de Déu
Fundació Sant Joan de Déu
r-FSJD. Repositorio Institucional de Producción Científica de la Fundació Sant Joan de Déu
instname
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::4663e8e7572638372ddfc5dd3b82713f
https://www.pnas.org/content/112/52/15970
https://www.pnas.org/content/112/52/15970
Autor:
Goyette, P, Boucher, G, Mallon, D, Ellinghaus, E, Jostins, L, Huang, H, Ripke, S, Gusareva, ES, Annese, V, Hauser, SL, Oksenberg, JR, Thomsen, I, Leslie, S, Daly, MJ, Van Steen, K, Duerr, RH, Barrett, JC, McGovern, DPB, Schumm, LP, Traherne, JA, Carrington, MN, Kosmoliaptsis, V, Karlsen, TH, Franke, A, Rioux, JD, Abraham, C, Achkar, JP, Ahmad, T, Amininejad, L, Ananthakrishnan, AN, Andersen, V, Anderson, CA, Andrews, JM, Aumais, G, Baidoo, L, Baldassano, RN, Balschun, T, Bampton, PA, Barclay, M, Bayless, TM, Bethge, J, Bis, JC, Bitton, A, Brand, S, Brant, SR, Buning, C, Chew, A, Cho, JH, Cleynen, I, Cohain, A, Croft, A, D'Amato, M, Danese, S, De Jong, D, De Vos, M, Denapiene, G, Denson, LA, Devaney, KL, Dewit, O, D'Inca, R, Dubinsky, M, Edwards, C, Ellinghaus, D, Essers, J, Ferguson, LR, Festen, EA, Fleshner, P, Florin, T, Franchimont, D, Fransen, K, Gearry, R, Georges, M, Gieger, C, Glas, J
Publikováno v:
Goyette, P; Boucher, G; Mallon, D; Ellinghaus, E; Jostins, L; Huang, H; et al.(2015). High-density mapping of the MHC identifies a shared role for HLA-DRB1∗01:03 in inflammatory bowel diseases and heterozygous advantage in ulcerative colitis. Nature Genetics, 47(2), 172-179. doi: 10.1038/ng.3176. UCLA: Retrieved from: http://www.escholarship.org/uc/item/3k54v0pw
© 2015 Nature America, Inc. All rights reserved. Genome-wide association studies of the related chronic inflammatory bowel diseases (IBD) known as Crohn's disease and ulcerative colitis have shown strong evidence of association to the major histocom
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od_______325::78131da2272a37db1a042955d7b773c5
http://www.escholarship.org/uc/item/3k54v0pw
http://www.escholarship.org/uc/item/3k54v0pw
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