Zobrazeno 1 - 10
of 27
pro vyhledávání: '"Achim Trubiroha"'
Autor:
Isabelle Vandernoot, Sabine Costagliola, Nicoletta Giusti, Achim Trubiroha, Pierre Gillotay, Benoit Haerlingen, Robert Opitz
Publikováno v:
Thyroid, 29 (11
Background: Defects in embryonic development of the thyroid gland are a major cause for congenital hypothyroidism in human newborns, but the underlying molecular mechanisms are still poorly understood. Organ development relies on a tightly regulated
Autor:
Benoit Haerlingen, Isabelle Vandernoot, Sabine Costagliola, Pierre Gillotay, Angelo Molinaro, Meghna Shankar, Robert Opitz, Achim Trubiroha
Summary The thyroid plays an essential role in homeostasis and development, but the extrinsic regulation of its embryonic development remains poorly understood. Recently, we have identified the FGF and BMP pathways to be crucial for thyroid specifica
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7296ad4a7c8db762f9edbb9c20b500a2
https://doi.org/10.1101/2020.08.13.249540
https://doi.org/10.1101/2020.08.13.249540
Autor:
Robert Opitz, Isabelle Vandernoot, Achim Trubiroha, Pierre Gillotay, Véronique Janssens, Sabine Costagliola, Benoit Haerlingen
Publikováno v:
BioRxiv
BackgroundCongenital hypothyroidism (CH) due to thyroid dysgenesis is a frequent congenital endocrine disorder for which the molecular mechanisms remain unresolved in the far majority of cases. This situation reflects in part our still limited knowle
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0b57d0e66b3c9b2ac6b12a2af3912e08
Autor:
Nicoletta, Giusti, Pierre, Gillotay, Achim, Trubiroha, Robert, Opitz, Jacques-Emile, Dumont, Sabine, Costagliola, Xavier, De Deken
Publikováno v:
Molecular and cellular endocrinology. 500
Thyroid hormone (TH) synthesis requires extracellular hydrogen peroxide generated by the NADPH oxidases, DUOX1 and DUOX2, with maturation factors, DUOXA1 and DUOXA2. In zebrafish, only one duox and one duoxa gene are present. Using a thyroid-specific
Autor:
Benoit Haerlingen, Isabelle Vandernoot, Achim Trubiroha, Pierre Gillotay, Robert Opitz, Sabine Costagliola, Nicoletta Giusti
BackgroundDefects in embryonic development of the thyroid gland are a major cause for congenital hypothyroidism in human newborns but the underlying molecular mechanisms are still poorly understood. Organ development relies on a tightly regulated int
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::78d47431abf07bc5c699f20c43b76330
Autor:
Achim Trubiroha, Xavier De Deken, Pierre Gillotay, Nicoletta Giusti, Robert Opitz, Jacques Emile Dumont, Sabine Costagliola
Publikováno v:
Molecular and cellular endocrinology, 500
Thyroid hormone (TH) synthesis requires extracellular hydrogen peroxide generated by the NADPH oxidases, DUOX1 and DUOX2, with maturation factors, DUOXA1 and DUOXA2. In zebrafish, only one duox and one duoxa gene are present. Using a thyroid-specific
Autor:
Benoit Haerlingen, David Gacquer, X De Deken, Robert Opitz, Sabine Costagliola, Frédérick Libert, Achim Trubiroha, Anne Lefort, Pierre Gillotay, Nicoletta Giusti
Publikováno v:
Scientific Reports
Scientific Reports, Vol 8, Iss 1, Pp 1-19 (2018)
Scientific reports, 8 (1
Scientific Reports, Vol 8, Iss 1, Pp 1-19 (2018)
Scientific reports, 8 (1
The foregut endoderm gives rise to several organs including liver, pancreas, lung and thyroid with important roles in human physiology. Understanding which genes and signalling pathways regulate their development is crucial for understanding developm
Autor:
Achim Trubiroha, Jitka Tumova, Hiroaki Tanaka, Andrew C. Johnson, Werner Kloas, Vimal Kumar, Roman Grabic, Masaru Ihara, Hana Kocour Kroupova
Publikováno v:
Environmental Science & Technology. 49:2625-2638
Around 20 progestins (also called gestagens, progestogens, or progestagens) are used today in assisting a range of medical conditions from endometrial cancer to uterine bleeding and as an important component of oral contraception. These progestins ca
Autor:
Mark E. Samuels, Robert Opitz, Valérie Désilets, Johnny Deladoëy, Gregor Andelfinger, Sabine Costagliola, Rasha Abu-Khudir, Achim Trubiroha, Marc-Philip Hitz, Isabelle Vandernoot
Publikováno v:
Endocrinology, 1 (1
Congenital hypothyroidism caused by thyroid dysgenesis (CHTD) is a common congenital disorder with a birth prevalence of 1 case in 4000 live births, and up to 8% of individuals with CHTD have co-occurring congenital heart disease. Initially we found
Autor:
Valeska Contardo-Jara, Roman Grabic, Werner Kloas, Martin Kocour, Ilka Lutz, Hana Kocour Kroupova, Claudia Lorenz, Achim Trubiroha
Publikováno v:
Aquatic Toxicology. 154:154-162
The aim of the present study was to investigate the effects of the synthetic progestin levonorgestrel (LNG) on the reproductive endocrine system of a teleost fish, the roach (Rutilus rutilus). Pubertal roach were exposed for 28 days in a flow-through