Zobrazeno 1 - 10
of 84
pro vyhledávání: '"Achim Schnaufer"'
Autor:
Zandile Nare, Tessa Moses, Karl Burgess, Achim Schnaufer, Malcolm D. Walkinshaw, Paul A. M. Michels
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 13 (2023)
Previously, we reported the development of novel small molecules that are potent inhibitors of the glycolytic enzyme phosphofructokinase (PFK) of Trypanosoma brucei and related protists responsible for serious diseases in humans and domestic animals.
Externí odkaz:
https://doaj.org/article/e22a5f125b2a483da392dcbbf91fccdd
Publikováno v:
BMC Bioinformatics, Vol 22, Iss 1, Pp 1-14 (2021)
Abstract Background The advent of population-scale genome projects has revolutionized our biological understanding of parasitic protozoa. However, while hundreds to thousands of nuclear genomes of parasitic protozoa have been generated and analyzed,
Externí odkaz:
https://doaj.org/article/8ef751dc6a4c491db8803820bfe28099
Autor:
Caroline E. Dewar, Aitor Casas-Sanchez, Constentin Dieme, Aline Crouzols, Lee R. Haines, Álvaro Acosta-Serrano, Brice Rotureau, Achim Schnaufer
Publikováno v:
mBio, Vol 13, Iss 1 (2022)
ABSTRACT The single-celled parasite Trypanosoma brucei is transmitted by hematophagous tsetse flies. Life cycle progression from mammalian bloodstream form to tsetse midgut form and, subsequently, infective salivary gland form depends on complex deve
Externí odkaz:
https://doaj.org/article/b31523e0c3274e81b45f168cc5ce1867
Autor:
Pieter C Steketee, Emily A Dickie, James Iremonger, Kathryn Crouch, Edith Paxton, Siddharth Jayaraman, Omar A Alfituri, Georgina Awuah-Mensah, Ryan Ritchie, Achim Schnaufer, Tim Rowan, Harry P de Koning, Catarina Gadelha, Bill Wickstead, Michael P Barrett, Liam J Morrison
Publikováno v:
PLoS Pathogens, Vol 17, Iss 7, p e1009734 (2021)
Animal African Trypanosomiasis (AAT) is a debilitating livestock disease prevalent across sub-Saharan Africa, a main cause of which is the protozoan parasite Trypanosoma congolense. In comparison to the well-studied T. brucei, there is a major paucit
Externí odkaz:
https://doaj.org/article/d876db67785745d3836a0959a9e3e077
Autor:
Philippe Büscher, Mary Isabel Gonzatti, Laurent Hébert, Noboru Inoue, Ilaria Pascucci, Achim Schnaufer, Keisuke Suganuma, Louis Touratier, Nick Van Reet
Publikováno v:
Parasites & Vectors, Vol 12, Iss 1, Pp 1-8 (2019)
Abstract Equine trypanosomosis is a complex of infectious diseases called dourine, nagana and surra. It is caused by several species of the genus Trypanosoma that are transmitted cyclically by tsetse flies, mechanically by other haematophagous flies,
Externí odkaz:
https://doaj.org/article/85cb3fac0f9a47afaa0d53a125ea480d
Mitochondrial DNA is critical for longevity and metabolism of transmission stage Trypanosoma brucei.
Autor:
Caroline E Dewar, Paula MacGregor, Sinclair Cooper, Matthew K Gould, Keith R Matthews, Nicholas J Savill, Achim Schnaufer
Publikováno v:
PLoS Pathogens, Vol 14, Iss 7, p e1007195 (2018)
The sleeping sickness parasite Trypanosoma brucei has a complex life cycle, alternating between a mammalian host and the tsetse fly vector. A tightly controlled developmental programme ensures parasite transmission between hosts as well as survival w
Externí odkaz:
https://doaj.org/article/6bf39bc3042942c99171eaff26092736
Autor:
Christine M Kamidi, Norah P Saarman, Kirstin Dion, Paul O Mireji, Collins Ouma, Grace Murilla, Serap Aksoy, Achim Schnaufer, Adalgisa Caccone
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 11, Iss 9, p e0005895 (2017)
Trypanosoma evansi is the parasite causing surra, a form of trypanosomiasis in camels and other livestock, and a serious economic burden in Kenya and many other parts of the world. Trypanosoma evansi transmission can be sustained mechanically by taba
Externí odkaz:
https://doaj.org/article/1d7850e93940471698134c9bb127d697
Autor:
Anthonius A Eze, Matthew K Gould, Jane C Munday, Daniel N A Tagoe, Valters Stelmanis, Achim Schnaufer, Harry P De Koning
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 10, Iss 8, p e0004791 (2016)
Isometamidium is the main prophylactic drug used to prevent the infection of livestock with trypanosomes that cause Animal African Trypanosomiasis. As well as the animal infective trypanosome species, livestock can also harbor the closely related hum
Externí odkaz:
https://doaj.org/article/6ef9436e90d64a19a69247683d0f18b2
Autor:
Roman Trikin, Nicholas Doiron, Anneliese Hoffmann, Beat Haenni, Martin Jakob, Achim Schnaufer, Bernd Schimanski, Benoît Zuber, Torsten Ochsenreiter
Publikováno v:
PLoS Pathogens, Vol 12, Iss 7, p e1005750 (2016)
[This corrects the article DOI: 10.1371/journal.ppat.1005586.].
Externí odkaz:
https://doaj.org/article/b4f0c78525aa434f80a4cfd2e6e88c12
Autor:
Bart Cuypers, Laurence Lecordier, Conor J. Meehan, Frederik Van den Broeck, Hideo Imamura, Philippe Büscher, Jean-Claude Dujardin, Kris Laukens, Achim Schnaufer, Caroline Dewar, Michael Lewis, Oliver Balmer, Thomas Azurago, Sardick Kyei-Faried, Sally-Ann Ohene, Boateng Duah, Prince Homiah, Ebenezer Kofi Mensah, Francis Anleah, Jose Ramon Franco, Etienne Pays, Stijn Deborggraeve
Publikováno v:
mBio, Vol 7, Iss 2 (2016)
ABSTRACT African trypanosomes, except Trypanosoma brucei gambiense and Trypanosoma brucei rhodesiense, which cause human African trypanosomiasis, are lysed by the human serum protein apolipoprotein L1 (ApoL1). These two subspecies can resist human Ap
Externí odkaz:
https://doaj.org/article/16ed32b2f6534b7296f6ac0683f6f5da