Zobrazeno 1 - 10
of 27
pro vyhledávání: '"Achim M. Vogt"'
Autor:
H. Möllmann, C Hamm, Albrecht Elsässer, Christian Troidl, Sandra Voss, Michael Weber, Achim M. Vogt, H. M. Nef, A Joseph
Publikováno v:
Journal of International Medical Research. 36:986-991
2-Deoxy-d-glucose (2-DG) is a glucose analogue that has been proposed for cancer therapy due to its cytostatic properties. Its effect on the proliferation of smooth muscle cells and endothelial cells has not been fully clarified. The aims of this stu
Autor:
Felix T. Wieland, Achim M. Vogt, Hugo A. Katus, Sven Y. Vetter, Albrecht Elsässer, Wolfgang Kübler, Anja Pott, Cordula Ackermann, Wolfgang Schoels, Constanze Reinhard, Sabrina C Lang, Osman Tutdibi
Publikováno v:
Molecular and Cellular Biochemistry. 285:191-196
Background: There is increasing evidence that mitochondria – owning a high degree of autonomy within the cell – might represent the target organelles of the myocardial protection afforded by ischemic preconditioning. It was the aim of the study t
Autor:
Thomas Wieland, Feraydoon Niroomand, Hans-Joerg Hippe, Achim M. Vogt, Friederike Cuello, Karl Jakobs, Susanne Lutz, Katrin Knorr
Publikováno v:
Journal of Biological Chemistry. 278:7220-7226
G protein betagamma dimers can be phosphorylated in membranes from various tissues by GTP at a histidine residue in the beta subunit. The phosphate is high energetic and can be transferred onto GDP leading to formation of GTP. Purified Gbetagamma dim
Autor:
Wolfgang Schoels, Cordula Ackermann, Murat Yildiz, Wolfgang Kübler, David A. Fell, Achim M. Vogt, Mark G. Poolman
Publikováno v:
Journal of Biological Chemistry. 277:24411-24419
Exact adjustment of the Embden-Meyerhof pathway (EMP) is an important issue in ischemic preconditioning (IP) because an attenuated ischemic lactate accumulation contributes to myocardial protection. However, precise mechanisms of glycolytic flux and
Autor:
Albrecht Elsässer, Achim M. Vogt, Wolfgang Kübler, Jutta Schaper, Holger Nef, David A. Fell, Mark G. Poolman
Publikováno v:
FEBS Letters. 517:245-250
Myocardial hibernation represents an adaptation to sustained ischemia to maintain tissue vitality during severe supply–demand imbalance which is characterized by an increased glucose uptake. To elucidate this adaptive protective mechanism, the regu
Publikováno v:
Zeitschrift für Kardiologie. 91:357-362
Trotz der zunehmenden Achtung des Dopings im Spitzensport ist im Breitensport eine hohe Dunkelziffer der Einnahme leistungssteigernder Praparate zu befurchten. Dies trifft vor allem auf solche „Sportarten” zu, die vorrangig dem Ziel dienen, einen
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease. 1586(2):219-226
In ischemia, the myocardial metabolic status determines the expansion of necrosis. Decreased ATP levels and increased lactate contents in ischemic myocardium undergoing lethal injury are known to be related to the expansion of irreversible damage. Ho
Autor:
Achim M. Vogt, Wolfgang Kübler, Christiane P. Tiefenbacher, Christian F. Vahl, Kerstin Amann, Tina Bleeke
Publikováno v:
Circulation. 102:2172-2179
Background —Tetrahydrobiopterin (BH4), an essential cofactor for the synthesis of NO, improves endothelial dysfunction after ischemia/reperfusion. Therefore, we hypothesized that reduction of BH4 is involved in the attenuation of endothelium-depend
Autor:
Achim M. Vogt, Wolfgang Kübler
Publikováno v:
Heart Failure Reviews. 4:211-219
For more than two millenniums, the beating heart is considered as a sign and symbol of life and vitality. Due to its central role for the individual life, both scientists as well as philosophers were engaged evolving concepts to explain cardiac funct
Publikováno v:
Journal of the American College of Cardiology. 31:1134-1141
This study sought to investigate the myocardial mechanisms causing refractoriness to ischemic preconditioning in pigs.Ischemic preconditioning in the pig vanishes after 60 min and cannot be reinstated by a second cycle of brief coronary occlusions at