Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Achim Gärtner"'
Autor:
Guy J. Georges, Stefan Dengl, Alexander Bujotzek, Friederike Hesse, Jens A.A. Fischer, Achim Gärtner, Jörg Benz, Matthias E. Lauer, Philippe Ringler, Henning Stahlberg, Friederike Plath, Ulrich Brinkmann, Sabine Imhof-Jung
Publikováno v:
Computational and Structural Biotechnology Journal, Vol 18, Iss , Pp 1210-1220 (2020)
The careful design of the antibody architecture is becoming more and more important, especially when the purpose is agonism. We present the design of a novel antibody format that is able to promote receptor dimerization and induce signal transduction
Externí odkaz:
https://doaj.org/article/e63a7374d4ac4858b91e6da04a61a06c
Autor:
Kilian Mayr, Thomas Weindl, Achim Gärtner, Julien Camperi, Thomas Maetzke, Markus Förster, Thomas Nachtigall, Frank Steiner, Annette Vogt, Fabian Hosp, Michael Mølhøj
Publikováno v:
Analytical Chemistry. 95:3629-3637
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::35c72bd5d865da444a3c987bc539d878
https://doi.org/10.1021/acs.analchem.2c04467
https://doi.org/10.1021/acs.analchem.2c04467
Autor:
Nadine Ruderisch, Daniel Schlatter, Andreas Kuglstatter, Wolfgang Guba, Sylwia Huber, Carlo Cusulin, Jörg Benz, Arne Christian Rufer, Joerg Hoernschemeyer, Christophe Schweitzer, Tina Bülau, Achim Gärtner, Eike Hoffmann, Jens Niewoehner, Christoph Patsch, Karlheinz Baumann, Hansruedi Loetscher, Eric Kitas, Per-Ola Freskgård
Publikováno v:
EBioMedicine, Vol 24, Iss C, Pp 76-92 (2017)
Therapeutic approaches to fight Alzheimer's disease include anti-Amyloidβ (Aβ) antibodies and secretase inhibitors. However, the blood-brain barrier (BBB) limits the brain exposure of biologics and the chemical space for small molecules to be BBB p
Externí odkaz:
https://doaj.org/article/316ddf067d1746b19366ae2a8f354fcb
Autor:
Henning Stahlberg, Jörg Benz, Jens Fischer, Guy Georges, Stefan Dengl, Alexander Bujotzek, Ulrich Brinkmann, Sabine Imhof-Jung, Achim Gärtner, Friederike Hesse, Philippe Ringler, Matthias E. Lauer, Friederike Plath
Publikováno v:
Computational and Structural Biotechnology Journal, Vol 18, Iss, Pp 1210-1220 (2020)
Computational and Structural Biotechnology Journal
Computational and Structural Biotechnology Journal
Graphical abstract Contorsbodyis an IgG-derived format which has both Fab arms tethered in close proximity to the carboxy-terminus of the CH3 domain of the Fc. Contorsbodiescan be produced by technologies applicable to regular antibodies. They have a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::09255c21784d3d1cb7f2803e83e23da6
https://edoc.unibas.ch/79287/
https://edoc.unibas.ch/79287/
Autor:
Christophe Schweitzer, Christoph Patsch, Joerg Hoernschemeyer, Eric A. Kitas, Eike Hoffmann, Jens Niewoehner, Nadine Ruderisch, Karlheinz Baumann, Sylwia Huber, Per-Ola Freskgard, Hansruedi Loetscher, Jörg Benz, Achim Gärtner, Arne C. Rufer, Carlo Cusulin, Tina Bülau, Andreas Kuglstatter, Wolfgang Guba, Daniel Schlatter
Publikováno v:
EBioMedicine
EBioMedicine, Vol 24, Iss C, Pp 76-92 (2017)
EBioMedicine, Vol 24, Iss C, Pp 76-92 (2017)
Therapeutic approaches to fight Alzheimer's disease include anti-Amyloidβ (Aβ) antibodies and secretase inhibitors. However, the blood-brain barrier (BBB) limits the brain exposure of biologics and the chemical space for small molecules to be BBB p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::84ad5bf832352c9060ecd331ea0b6c7b
https://doi.org/10.1016/j.ebiom.2017.09.004
https://doi.org/10.1016/j.ebiom.2017.09.004
Autor:
Christian Klein, Vincent Beuger, Klaus-Peter Künkele, Monika Bähner, Helmut Burtscher, Hans Koll, Achim Gärtner
Publikováno v:
Biotechnology and Applied Biochemistry. 53:31
Antibody-producing Chinese-hamster ovary cells (CHO-DG44) were converted into cells producing antibodies with strongly enhanced ADCC (antibody-dependent cellular cytotoxicity) by knocking down FuT8 (alpha-1,6-fucosyltransferase or fucosyltransferase
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e853513ae7a25650e9caede54336ea5e
https://doi.org/10.1042/ba20080220
https://doi.org/10.1042/ba20080220
Autor:
Vincent Beuger, Klaus-Peter Künkele, Hans Koll, Achim Gärtner, Monika Bähner, Helmut Burtscher, Christian Klein
Publikováno v:
Biotechnology & Applied Biochemistry; May2009, Vol. 53 Issue 1, p31-37, 7p
Autor:
Regula, Joerg Thomas, Imhof-Jung, Sabine, Mølhøj, Michael, Benz, Joerg, Ehler, Andreas, Bujotzek, Alexander, Schaefer, Wolfgang, Klein, Christian
Publikováno v:
PEDS: Protein Engineering, Design & Selection; Jul/Aug2018, Vol. 31 Issue 7/8, p289-299, 11p
Autor:
Gero Pflüger
Mit Social Media in die Herzen Ihrer Kunden Kein Zweifel: Über soziale Medien erreichen Sie Ihre Kunden authentisch und persönlich. Allerdings ist die Komplexität von Social-Media-Marketing hoch und die Gefahr groß, Zeit und Geld zu verpulvern. D
Autor:
Verena Jaeschke
Die Studie untersucht den Ausbau der tetrarchischen Residenzstädte Nicomedia, Sirmium, Antiochia, Thessalonica, Serdica, Augusta Treverorum, Mediolanum und Aquileia im späten 3. und 4. Jahrhundert n. Chr. Zentral ist hierbei die Frage, inwiefern di