Zobrazeno 1 - 10
of 86
pro vyhledávání: '"Achim Dickmanns"'
Autor:
Ethiraj Ravindran, Gaetan Lesca, Louis Januel, Linus Goldgruber, Achim Dickmanns, Henri Margot, Angela M. Kaindl
Publikováno v:
Frontiers in Neurology, Vol 14 (2023)
Nucleoporin (NUP) 85 is a member of the Y-complex of nuclear pore complex (NPC) that is key for nucleocytoplasmic transport function, regulation of mitosis, transcription, and chromatin organization. Mutations in various nucleoporin genes have been l
Externí odkaz:
https://doaj.org/article/ed1e140840424257b23b4291c8670577
Autor:
Ethiraj Ravindran, Nobuto Arashiki, Lena-Luise Becker, Kohtaro Takizawa, Jonathan Lévy, Thomas Rambaud, Konstantin L Makridis, Yoshio Goshima, Na Li, Maaike Vreeburg, Bénédicte Demeer, Achim Dickmanns, Alexander PA Stegmann, Hao Hu, Fumio Nakamura, Angela M Kaindl
Publikováno v:
eLife, Vol 11 (2022)
Collapsin response mediator proteins (CRMPs) are key for brain development and function. Here, we link CRMP1 to a neurodevelopmental disorder. We report heterozygous de novo variants in the CRMP1 gene in three unrelated individuals with muscular hypo
Externí odkaz:
https://doaj.org/article/c98656144c6a4ee89eb96a7359dd7037
Autor:
Larissa Krüger, Christina Herzberg, Dennis Wicke, Heike Bähre, Jana L. Heidemann, Achim Dickmanns, Kerstin Schmitt, Ralf Ficner, Jörg Stülke
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-12 (2021)
In several bacteria, cyclic di-AMP mediates potassium (K+) and osmotic homeostasis. Here, the authors show that DarB, a Bacillus subtilis protein previously reported to bind cyclic di-AMP, interacts with the (p)ppGpp synthetase/hydrolase Rel in a K+-
Externí odkaz:
https://doaj.org/article/09902e6043b6418cada4e487ae632736
Autor:
Roshan Priyarangana Perera, Alaa Shaikhqasem, Nadia Rostam, Achim Dickmanns, Ralf Ficner, Kai Tittmann, Roland Dosch
Publikováno v:
Biomolecules, Vol 11, Iss 10, p 1507 (2021)
Many multicellular organisms specify germ cells during early embryogenesis by the inheritance of ribonucleoprotein (RNP) granules known as germplasm. However, the role of complex interactions of RNP granules during germ cell specification remains elu
Externí odkaz:
https://doaj.org/article/d6eb163b6cc24fed8b2e280df3c08cb9
Autor:
Edith Bonnin, Pauline Cabochette, Alessandro Filosa, Ramona Jühlen, Shoko Komatsuzaki, Mohammed Hezwani, Achim Dickmanns, Valérie Martinelli, Marjorie Vermeersch, Lynn Supply, Nuno Martins, Laurence Pirenne, Gianina Ravenscroft, Marcus Lombard, Sarah Port, Christiane Spillner, Sandra Janssens, Ellen Roets, Jo Van Dorpe, Martin Lammens, Ralph H Kehlenbach, Ralf Ficner, Nigel G Laing, Katrin Hoffmann, Benoit Vanhollebeke, Birthe Fahrenkrog
Publikováno v:
PLoS Genetics, Vol 14, Iss 12, p e1007845 (2018)
Nucleoporins build the nuclear pore complex (NPC), which, as sole gate for nuclear-cytoplasmic exchange, is of outmost importance for normal cell function. Defects in the process of nucleocytoplasmic transport or in its machinery have been frequently
Externí odkaz:
https://doaj.org/article/88c96d3ae2aa45ddb907f5a735313301
Autor:
Sarah A. Port, Thomas Monecke, Achim Dickmanns, Christiane Spillner, Romina Hofele, Henning Urlaub, Ralf Ficner, Ralph H. Kehlenbach
Publikováno v:
Cell Reports, Vol 13, Iss 4, Pp 690-702 (2015)
CRM1 is the major nuclear export receptor. During translocation through the nuclear pore, transport complexes transiently interact with phenylalanine-glycine (FG) repeats of multiple nucleoporins. On the cytoplasmic side of the nuclear pore, CRM1 tig
Externí odkaz:
https://doaj.org/article/b9e3ebdaa4eb4fa9bd017adef6b43a68
Publikováno v:
Cells, Vol 4, Iss 3, Pp 538-568 (2015)
Recent studies have demonstrated the interference of nucleocytoplasmic trafficking with the establishment and maintenance of various cancers. Nucleocytoplasmic transport is highly regulated and coordinated, involving different nuclear transport facto
Externí odkaz:
https://doaj.org/article/f6a4a454e02f4e84b5a0d7c6710c12d5
Autor:
Yasar Luqman Ahmed, Jennifer Gerke, Hee-Soo Park, Özgür Bayram, Piotr Neumann, Min Ni, Achim Dickmanns, Sun Chang Kim, Jae-Hyuk Yu, Gerhard H Braus, Ralf Ficner
Publikováno v:
PLoS Biology, Vol 11, Iss 12, p e1001750 (2013)
Morphological development of fungi and their combined production of secondary metabolites are both acting in defence and protection. These processes are mainly coordinated by velvet regulators, which contain a yet functionally and structurally unchar
Externí odkaz:
https://doaj.org/article/42c5c30ca5314eb29550a7485a1cacd3
Publikováno v:
Biological Chemistry.
Soluble nuclear transport receptors and stationary nucleoporins are at the heart of the nucleocytoplasmic transport machinery. A subset of nucleoporins contains characteristic and repetitive FG (phenylalanine-glycine) motifs, which are the basis for
Autor:
Kohtaro Takizawa, Lena-Luise Becker, Nobuto Arashiki, Ethiraj Ravindran, Jonathan Lévy, Thomas Rambaud, Konstantin L Makridis, Yoshio Goshima, Na Li, Maaike Vreeburg, Bénédicte Demeer, Achim Dickmanns, Alexander PA Stegmann, Hao Hu, Fumio Nakamura, Angela M Kaindl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::31cffedccc64636e7b1c0e0ac574cf46
https://doi.org/10.7554/elife.80793.sa2
https://doi.org/10.7554/elife.80793.sa2